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Showing 1 to 12 of 61 entries
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Red Lentil Extract: Neuroprotective Effects on Perphenazine Induced Catatonia in Rats.

Journal of clinical and diagnostic research : JCDR

Houshmand G, Tarahomi S, Arzi A, Goudarzi M, Bahadoram M, Rashidi-Nooshabadi M.
PMID: 27504309
J Clin Diagn Res. 2016 Jun;10(6):FF05-8. doi: 10.7860/JCDR/2016/17813.7977. Epub 2016 Jun 01.

INTRODUCTION: Parkinsonism is a neurodegenerative disease that is defined by certain symptoms such as muscle rigidity, impaired movement, catatonia, tremor and disorientation of body.AIM: The aim was to investigate the effect of red lentil extract on perphenazine-induced Catatonia in...

A comparison of cardiovascular risk factors for ten antipsychotic drugs in clinical practice.

Neuropsychiatric disease and treatment

Bodén R, Edman G, Reutfors J, Ostenson CG, Osby U.
PMID: 23682213
Neuropsychiatr Dis Treat. 2013;9:371-7. doi: 10.2147/NDT.S40554. Epub 2013 Mar 19.

It is well known that abdominal obesity, dyslipidemia, and insulin resistance are highly prevalent in patients receiving maintenance treatment with antipsychotics, but there is limited knowledge about the association between cardiovascular risk factors and treatment with antipsychotic drugs. In...

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Tomillero A, Moral MA.
PMID: 18985183
Methods Find Exp Clin Pharmacol. 2008 Sep;30(7):543-88.

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug...

Electrochemical study and detection of perphenazine using a gold electrode modified with decanethiol SAM.

Talanta

Zeng B, Yang Y, Ding X, Zhao F.
PMID: 18969247
Talanta. 2003 Dec 23;61(6):819-27. doi: 10.1016/S0039-9140(03)00381-3.

A novel method for the determination of perphenazine has been developed. The method is based on the accumulation of perphenazine at a gold electrode modified with decanethiol (DEC) self-assembled monolayer (SAM) and its oxidation at about 0.6 V (vs....

Chemiluminescence method for the assay of perphenazine in drug formulation using permanganate in sulphuric acid with flow injection technique and a chemometrical optimization approach.

Talanta

Sultan SM, Abdennabi AM, Almuaibed AM.
PMID: 18967682
Talanta. 1999 Aug 09;49(5):1051-7. doi: 10.1016/s0039-9140(99)00045-4.

An accurate selective flow injection chemiluminescence (CL) method for the assay of perphenazine was explored. In the method 394 ppm permanganate solution was used as a chemiluminogenic reagent in 0.289 mol dm(-3) sulphuric acid media. A photomultiplier tube was...

Titrimetric determination of some phenothiazine derivatives, with ferricyanide.

Talanta

Issa AS, Mahrous MS.
PMID: 18963590
Talanta. 1984 Apr;31(4):287-8. doi: 10.1016/0039-9140(84)80280-5.

Six phenothiazine drugs (chlorpromazine hydrochloride, promethazine hydrochloride, promazine hydrochloride, perphenazine, acetophenazine maleate and trifluoperazine hydrochloride) have been determined by titration with potassium ferricyanide in phosphoric acid medium with Methylene Blue as a screening indicator. The results were in agreement...

Sensitive determination of phenothiazines in pharmaceutical preparation and biological fluid by flow injection chemiluminescence method using luminol-KMnO(4) system.

Talanta

Li Y, Niu W, Lu J.
PMID: 19071422
Talanta. 2007 Feb 28;71(3):1124-9. doi: 10.1016/j.talanta.2006.06.007. Epub 2006 Jul 17.

A flow injection chemiluminescence method was described for the determination of four phenothiazine drugs, namely, chlorpromazine hydrochloride, perphenazine hydrochloride, fluphenazine hydrochloride and thioridazine hydrochloride. Strong Chemiluminescence (CL) signal was produced when above-mentioned drug was injected into the mixed stream...

Antipsychotic-induced priapism in an HIV patient: a cytochrome P450-mediated drug interaction.

International journal of emergency medicine

Geraci MJ, McCoy SL, Crum PM, Patel RA.
PMID: 20606815
Int J Emerg Med. 2010 May 26;3(2):81-4. doi: 10.1007/s12245-010-0175-y.

BACKGROUND: With upwards of 48% of human immunodeficiency virus (HIV)-infected persons having a probable psychiatric disorder, the possibility of cross-class drug interactions causing adverse effects or fatalities exists.AIMS: This report discusses an emergent case of low-flow priapism caused by...

A review of a recently published guidelines' "strong recommendation" for therapeutic drug monitoring of olanzapine, haloperidol, perphenazine, and fluphenazine.

The mental health clinician

Noel C.
PMID: 31293849
Ment Health Clin. 2019 Jul 01;9(4):287-293. doi: 10.9740/mhc.2019.07.287. eCollection 2019 Jul.

INTRODUCTION: In addition to clozapine, there is a growing body of evidence that supports therapeutic drug monitoring (TDM) for additional antipsychotics commonly used in the United States.METHODS: The Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie (AGNP) published TDM guidelines for several...

Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles.

Biological & pharmaceutical bulletin

Obara K, Matsuoka Y, Iwata N, Abe Y, Ikegami Y, Shioda N, Hattori Y, Hamamatsu S, Yoshioka K, Yamaki F, Matsuo K, Yoshio T, Tanaka Y.
PMID: 34334499
Biol Pharm Bull. 2021;44(8):1140-1150. doi: 10.1248/bpb.b21-00363.

The clinical applications of antipsychotics for symptoms unrelated to schizophrenia, such as behavioral and psychological symptoms, in patients with Alzheimer's disease, and the likelihood of doctors prescribing antipsychotics for elderly people are increasing. In elderly people, drug-induced and aging-associated...

In vitro anticancer activity of fluphenazine, perphenazine and prochlorperazine. A review.

Journal of applied toxicology : JAT

Otręba M, Kośmider L.
PMID: 32852120
J Appl Toxicol. 2021 Jan;41(1):82-94. doi: 10.1002/jat.4046. Epub 2020 Aug 27.

Drug repositioning is an approach that could accelerate the clinical use of compounds in different diseases. The goal is to take advantage of the fact that approved drugs have been tested on humans and detailed information is available on...

Perphenazine exerts antitumor effects on HUT78 cells through Akt dephosphorylation by protein phosphatase 2A.

Oncology letters

Tsuji S, Kohyanagi N, Mizuno T, Ohama T, Sato K.
PMID: 33376545
Oncol Lett. 2021 Feb;21(2):113. doi: 10.3892/ol.2020.12374. Epub 2020 Dec 15.

Sezary syndrome is a rare type of non-Hodgkin lymphoma. Protein phosphatase 2A (PP2A) is an important tumor suppressor whose activity is widely inhibited in a variety of tumors. Recently, reactivation of PP2A has attracted increasing attention as a promising...

Showing 1 to 12 of 61 entries