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Showing 1 to 12 of 860 entries
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Influence of chronic inflammation on Bcl-2 and PCNA expression in prostate needle biopsy specimens.

Oncology letters

Glover M, Soni S, Ren Q, Maclennan GT, Fu P, Gupta S.
PMID: 28943900
Oncol Lett. 2017 Oct;14(4):3927-3934. doi: 10.3892/ol.2017.6668. Epub 2017 Jul 26.

The association between inflammation and cancer has been established in certain forms of human malignancies; however, its role in prostate cancer remains unclear. The present study investigates a possible association between chronic inflammation and the development of epithelial neoplasia...

Possible carcinogenic potential of dimethyl dimethoxy biphenyl dicarboxylate in experimental animals.

Journal of advanced pharmaceutical technology & research

Botros SS, El-Lakkany NM, Hammam OA, Sabra AN, Taha AA.
PMID: 27144153
J Adv Pharm Technol Res. 2016 Apr-Jun;7(2):54-8. doi: 10.4103/2231-4040.179747.

Dimethyl dimethoxy biphenyl dicarboxylate (DDB) has been extensively used in the treatment of liver diseases accounting for 1-6% of the global disease burden. Cell replication, DNA synthesis, and proliferation, providing significant information about behavior of cells were examined in...

Immunohistochemical expression of vascular endothelial growth factor in canine oral squamous cell carcinomas.

Oncology letters

Martano M, Restucci B, Ceccarelli DM, Lo Muzio L, Maiolino P.
PMID: 26870224
Oncol Lett. 2016 Jan;11(1):399-404. doi: 10.3892/ol.2015.3847. Epub 2015 Oct 30.

Angiogenesis is crucial for the growth and metastasis of malignant tumours, and various proangiogenic factors promote this process. One of these factors is vascular endothelial growth factor (VEGF), which appears to play a key role in tumour angiogenesis. The...

Proliferating Cell Nuclear Antigen in Premalignancy and Oral Squamous Cell Carcinoma.

Journal of clinical and diagnostic research : JCDR

Poosarla C, Ramesh M, Ramesh K, Gudiseva S, Bala S, Sundar M.
PMID: 26266215
J Clin Diagn Res. 2015 Jun;9(6):ZC39-41. doi: 10.7860/JCDR/2015/12645.6094. Epub 2015 Jun 01.

INTRODUCTION: Cancer has multifactorial aetiology and is a multistep process involving initiation, promotion and tumour progression. Cellular proliferation is one of the important indicators for the biologic aggressiveness of a malignant lesion. The dysregulated proliferation may be a significant...

Age-associated prognostic and predictive biomarkers in patients with breast cancer.

Oncology letters

Kolečková M, Kolář Z, Ehrmann J, Kořínková G, Trojanec R.
PMID: 28599421
Oncol Lett. 2017 Jun;13(6):4201-4207. doi: 10.3892/ol.2017.6000. Epub 2017 Apr 06.

To date, no comprehensive prognostic or predictive marker profiling analysis has been performed in association with the age of patients with breast cancer. In the present study, 632 breast cancer tissue samples were analyzed for expression of estrogen receptor...

Characterization of mesenchymal cells beneath cornification of the fetal epithelium and epidermis at the face: an immunohistochemical study using human fetal specimens.

Anatomy & cell biology

Kim JH, Jin ZW, Murakami G, Cho BH.
PMID: 27051567
Anat Cell Biol. 2016 Mar;49(1):50-60. doi: 10.5115/acb.2016.49.1.50. Epub 2016 Mar 28.

Fetal development of the face involves a specific type of cornification in which keratinocytes provide a mass or plug to fill a cavity. The epithelial-mesenchymal interaction was likely to be different from that in the usual skin. We examined...

Involvement of receptor-interacting protein 140 in palmitate-stimulated macrophage infiltration of pancreatic beta cells.

Experimental and therapeutic medicine

Zou R, Xue J, Huang Q, Dai Z, Xu Y.
PMID: 28672957
Exp Ther Med. 2017 Jul;14(1):483-494. doi: 10.3892/etm.2017.4544. Epub 2017 Jun 02.

Receptor-interacting protein 140 (RIP140) in macrophages stimulates the nuclear factor-κB subunit RelA to activate tumor necrosis factor (TNF)-α and interleukin (IL)-6 transcription. However, under lipotoxic conditions, the involvement of RIP140 in the infiltration of beta cells by macrophages remains...

Acylcarnitine profiles in acetaminophen toxicity in the mouse: comparison to toxicity, metabolism and hepatocyte regeneration.

Metabolites

Bhattacharyya S, Pence L, Beger R, Chaudhuri S, McCullough S, Yan K, Simpson P, Hennings L, Hinson J, James L.
PMID: 24958141
Metabolites. 2013 Aug 02;3(3):606-22. doi: 10.3390/metabo3030606.

High doses of acetaminophen (APAP) result in hepatotoxicity that involves metabolic activation of the parent compound, covalent binding of the reactive intermediate N-acetyl-p-benzoquinone imine (NAPQI) to liver proteins, and depletion of hepatic glutathione. Impaired fatty acid β-oxidation has been...

Luteolin Ameliorates Hypertensive Vascular Remodeling through Inhibiting the Proliferation and Migration of Vascular Smooth Muscle Cells.

Evidence-based complementary and alternative medicine : eCAM

Su J, Xu HT, Yu JJ, Gao JL, Lei J, Yin QS, Li B, Pang MX, Su MX, Mi WJ, Chen SH, Lv GY.
PMID: 26495010
Evid Based Complement Alternat Med. 2015;2015:364876. doi: 10.1155/2015/364876. Epub 2015 Sep 30.

Objectives. Preliminary researches showed that luteolin was used to treat hypertension. However, it is still unclear whether luteolin has effect on the hypertensive complication such as vascular remodeling. The present study was designed to investigate the effect of luteolin...

An Egr-1-specific DNAzyme regulates Egr-1 and proliferating cell nuclear antigen expression in rat vascular smooth muscle cells.

Experimental and therapeutic medicine

Zhang J, Guo C, Wang R, Huang L, Liang W, Liu R, Sun B.
PMID: 23737882
Exp Ther Med. 2013 May;5(5):1371-1374. doi: 10.3892/etm.2013.1013. Epub 2013 Mar 15.

The aim of the present study was to transfect rat aortic smooth muscle cells with an early growth response factor-1 (Egr-1)-specific DNAzyme (ED5), to observe its effect on Egr-1 and proliferating cell nuclear antigen (PCNA) expression and to elucidate...

Molecular modeling and expression of the Litopenaeus vannamei proliferating cell nuclear antigen (PCNA) after white spot syndrome virus shrimp infection.

Results in immunology

de-la-Re-Vega E, Muhlia-Almazan A, Arvizu-Flores AA, Islas-Osuna MA, Yepiz-Plascencia G, Brieba LG, Sotelo-Mundo RR.
PMID: 24371549
Results Immunol. 2011 Jul 26;1(1):24-30. doi: 10.1016/j.rinim.2011.07.001. eCollection 2011.

Proliferating cell nuclear antigen (PCNA) is the eukaryotic sliding clamp that tethers DNA polymerase to DNA during replication. The full-length cDNA of the Pacific white shrimp Litopenaeus vannamei PCNA (LvPCNA) was cloned and encoded a protein of 260 amino...

Ventromedial hypothalamic lesions enhance small intestinal cell proliferation in mice.

Obesity research & clinical practice

Ishizuka N, Senoo A, Hayashi K, Sasaki K, Kako M, Suzuki Y, Imazeki N, Shimizu H, Kobayashi Y, Haba R, Takahashi T, Arai K, Osaka T, Kintaka Y, Suzuki Y, Inoue S.
PMID: 24331527
Obes Res Clin Pract. 2012 Jul-Sep;6(3):e175-262. doi: 10.1016/j.orcp.2011.12.006.

BACKGROUND: We have found previously that ventromedial hypothalamic lesions (VMH) enhance cell proliferation in the visceral organs through vagal hyperactivity in rats. The goal of the current study was to determine the characteristics and nature of cell proliferation in...

Showing 1 to 12 of 860 entries