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Optogenetic pacing in Drosophila melanogaster.

Science advances

Alex A, Li A, Tanzi RE, Zhou C.
PMID: 26601299
Sci Adv. 2015 Oct 09;1(9):e1500639. doi: 10.1126/sciadv.1500639. eCollection 2015 Oct.

Electrical stimulation is currently the gold standard for cardiac pacing. However, it is invasive and nonspecific for cardiac tissues. We recently developed a noninvasive cardiac pacing technique using optogenetic tools, which are widely used in neuroscience. Optogenetic pacing of...

Optical Coherence Tomography for Brain Imaging and Developmental Biology.

IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society

Men J, Huang Y, Solanki J, Zeng X, Alex A, Jerwick J, Zhang Z, Tanzi RE, Li A, Zhou C.
PMID: 27721647
IEEE J Sel Top Quantum Electron. 2016 Jul-Aug;22(4). doi: 10.1109/JSTQE.2015.2513667. Epub 2015 Dec 30.

Optical coherence tomography (OCT) is a promising research tool for brain imaging and developmental biology. Serving as a three-dimensional optical biopsy technique, OCT provides volumetric reconstruction of brain tissues and embryonic structures with micrometer resolution and video rate imaging...

Recapitulating amyloid β and tau pathology in human neural cell culture models: clinical implications.

US neurology

Choi SH, Kim YH, D'Avanzo C, Aronson J, Tanzi RE, Kim DY.
PMID: 27019672
US Neurol. 2015;11(2):102-105. doi: 10.17925/USN.2015.11.02.102.

The "amyloid β hypothesis" of Alzheimer's disease (AD) has been the reigning hypothesis explaining pathogenic mechanisms of AD over the last two decades. However, this hypothesis has not been fully validated in animal models, and several major unresolved issues...

Showing 1 to 3 of 3 entries