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Showing 1 to 7 of 7 entries
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Testosterone increases circulating dehydroepiandrosterone sulfate levels in the male rhesus macaque.

Frontiers in endocrinology

Sorwell KG, Kohama SG, Urbanski HF.
PMID: 25009533
Front Endocrinol (Lausanne). 2014 Jun 25;5:101. doi: 10.3389/fendo.2014.00101. eCollection 2014.

The adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are two of the most abundant hormones in the human circulation. Furthermore, they are released in a circadian pattern and show a marked age-associated decline. Adult levels of DHEA and...

Spatial Memory Performance Associated with Measures of Immune Function in Elderly Female Rhesus Macaques.

European geriatric medicine

Haley GE, Urbanski HF, Kohama SG, Messaoudi I, Raber J.
PMID: 21603071
Eur Geriatr Med. 2011 Apr 01;2(2):117-121. doi: 10.1016/j.eurger.2011.01.002.

We recently reported that in aged female rhesus macaques, spatial learning and memory correlates with circadian sleep-wake measures and hippocampal muscarinic type 1 (M(1)) receptor binding. To investigate if spatial memory also correlates with measures of immune function, we...

Effect of an obesogenic diet on circadian activity and serum hormones in old monkeys.

Endocrine connections

Urbanski HF, Mueller K, Bethea CL.
PMID: 28619884
Endocr Connect. 2017 Aug;6(6):380-383. doi: 10.1530/EC-17-0108. Epub 2017 Jun 15.

Like women, old female rhesus macaques undergo menopause and show many of the same age-associated changes, including perturbed activity/rest cycles and altered circulating levels of many hormones. Previous studies showed that administration of an estrogen agonist increased activity in...

Impact of Moderate Calorie Restriction on the Reproductive Neuroendocrine Axis of Male Rhesus Macaques.

Open Longevity Science

Sitzmann BD, Mattison JA, Ingram DK, Roth GS, Ottinger MA, Urbanski HF.
PMID: 20814446
Open Longev Sci. 2010;3(10):38-47. doi: 10.2174/1876326X00903010038.

The impact of moderate calorie restriction on reproductive neuroendocrine function was investigated in young adult male rhesus macaques (Macaca mulatta). The animals were subjected to either 30% calorie restriction (CR; n=5), or were fed a standard control diet (CON;...

Effects of estradiol supplementation on the brain transcriptome of old rhesus macaques maintained on an obesogenic diet.

GeroScience

Cervera-Juanes R, Darakjian P, Ball M, Kohama SG, Urbanski HF.
PMID: 34642852
Geroscience. 2021 Oct 13; doi: 10.1007/s11357-021-00453-8. Epub 2021 Oct 13.

Obesity, the cessation of ovarian steroids with menopause, and age are risk factors for mood disorders, dementia, and Alzheimer's disease (AD). However, immediate hormone therapy (HT) after menopause may have beneficial effects in different brain regions involved in memory...

Differential roles of GnRH-I and GnRH-ii neurons in the control of the primate reproductive axis.

Frontiers in endocrinology

Urbanski HF.
PMID: 22645518
Front Endocrinol (Lausanne). 2012 Feb 07;3:20. doi: 10.3389/fendo.2012.00020. eCollection 2012.

In vertebrates, gonadotropin-releasing hormone (GnRH) represents the primary neuroendocrine link between the brain and the reproductive axis, and in some species up to three different forms of GnRH have been detected. Until recently, it had been assumed that humans...

Aging in male primates: reproductive decline, effects of calorie restriction and future research potential.

Age (Dordrecht, Netherlands)

Sitzmann BD, Urbanski HF, Ottinger MA.
PMID: 19424865
Age (Dordr). 2008 Sep;30(2):157-68. doi: 10.1007/s11357-008-9065-0. Epub 2008 Jul 09.

Although less dramatic than in females, male mammals experience decreasing reproductive function during aging. In primates, multiple facets of the hypothalamic-pituitary-gonadal axis show evidence of gradual age-related decline, including behavioral, neuroendocrine and endocrine alterations such as decreased testosterone levels,...

Showing 1 to 7 of 7 entries