Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 3 of 3 entries
Sorted by: Best Match Show Resources per page
Human Complement C4B Allotypes and Deficiencies in Selected Cases With Autoimmune Diseases.

Frontiers in immunology

Zhou D, Rudnicki M, Chua GT, Lawrance SK, Zhou B, Drew JL, Barbar-Smiley F, Armstrong TK, Hilt ME, Birmingham DJ, Passler W, Auletta JJ, Bowden SA, Hoffman RP, Wu YL, Jarjour WN, Mok CC, Ardoin SP, Lau YL, Yu CY.
PMID: 34764957
Front Immunol. 2021 Oct 26;12:739430. doi: 10.3389/fimmu.2021.739430. eCollection 2021.

Human complement C4 is one of the most diverse but heritable effectors for humoral immunity. To help understand the roles of C4 in the defense and pathogenesis of autoimmune and inflammatory diseases, we determined the bases of polymorphisms including...

The Influence of an Elastase-Sensitive Complement C5 Variant on Lupus Nephritis and Its Flare.

Kidney international reports

Toy CR, Song H, Nagaraja HN, Scott J, Greco J, Zhang X, Yu CY, Tumlin JA, Rovin BH, Hebert LA, Birmingham DJ.
PMID: 34386659
Kidney Int Rep. 2021 Jun 09;6(8):2105-2113. doi: 10.1016/j.ekir.2021.05.029. eCollection 2021 Aug.

INTRODUCTION: A C5 polymorphism (rs17611, 2404G>A) exists where the G allele associates with enhanced C5a-like production by neutrophil elastase. This cohort study investigated the influence of this polymorphism as a risk factor for lupus nephritis (LN), and on C5a...

Elevated serum complement levels and higher gene copy number of complement .

Lupus science & medicine

Mulvihill E, Ardoin S, Thompson SD, Zhou B, Yu GR, King E, Singer N, Levy DM, Brunner H, Wu YL, Nagaraja HN, Schanberg LE, Yu CY.
PMID: 31448126
Lupus Sci Med. 2019 Jul 31;6(1):e000333. doi: 10.1136/lupus-2019-000333. eCollection 2019.

OBJECTIVE: Systemic lupus erythematosus (SLE) features high frequency of cardiovascular disease (CVD) and fluctuating complement levels. The clinical trial Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) aimed to evaluate whether atorvastatin treatment reduced the progression of atherosclerosis in 221...

Showing 1 to 3 of 3 entries