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Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication.

Nature metabolism

Chu J, Xing C, Du Y, Duan T, Liu S, Zhang P, Cheng C, Henley J, Liu X, Qian C, Yin B, Wang HY, Wang RF.
PMID: 34580494
Nat Metab. 2021 Nov;3(11):1466-1475. doi: 10.1038/s42255-021-00479-4. Epub 2021 Sep 27.

Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19 is a virus-induced inflammatory disease of the airways and lungs that leads to severe multi-organ damage and death. Here we show that cellular lipid synthesis is required for SARS-CoV-2...

Cite
Chu J, Xing C, Du Y, et al. Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication. Nat Metab. 2021;3(11):1466-1475doi: 10.1038/s42255-021-00479-4.
Chu, J., Xing, C., Du, Y., Duan, T., Liu, S., Zhang, P., Cheng, C., Henley, J., Liu, X., Qian, C., Yin, B., Wang, H. Y., & Wang, R. F. (2021). Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication. Nature metabolism, 3(11), 1466-1475. https://doi.org/10.1038/s42255-021-00479-4
Chu, Junjun, et al. "Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication." Nature metabolism vol. 3,11 (2021): 1466-1475. doi: https://doi.org/10.1038/s42255-021-00479-4
Chu J, Xing C, Du Y, Duan T, Liu S, Zhang P, Cheng C, Henley J, Liu X, Qian C, Yin B, Wang HY, Wang RF. Pharmacological inhibition of fatty acid synthesis blocks SARS-CoV-2 replication. Nat Metab. 2021 Nov;3(11):1466-1475. doi: 10.1038/s42255-021-00479-4. Epub 2021 Sep 27. PMID: 34580494; PMCID: PMC8475461.
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