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Vitamin D as a Potential Preventive Agent For Young Women's Breast Cancer.

Cancer prevention research (Philadelphia, Pa.)

Bernhardt SM, Borges VF, Schedin P.
PMID: 34244152
Cancer Prev Res (Phila). 2021 Sep;14(9):825-838. doi: 10.1158/1940-6207.CAPR-21-0114. Epub 2021 Jul 09.

Clinical studies backed by research in animal models suggest that vitamin D may protect against the development of breast cancer, implicating vitamin D as a promising candidate for breast cancer prevention. However, despite clear preclinical evidence showing protective roles...

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Bernhardt SM, Borges VF, Schedin P. Vitamin D as a Potential Preventive Agent For Young Women's Breast Cancer. Cancer Prev Res (Phila). 2021;14(9):825-838doi: 10.1158/1940-6207.CAPR-21-0114.
Bernhardt, S. M., Borges, V. F., & Schedin, P. (2021). Vitamin D as a Potential Preventive Agent For Young Women's Breast Cancer. Cancer prevention research (Philadelphia, Pa.), 14(9), 825-838. https://doi.org/10.1158/1940-6207.CAPR-21-0114
Bernhardt, Sarah M, et al. "Vitamin D as a Potential Preventive Agent For Young Women's Breast Cancer." Cancer prevention research (Philadelphia, Pa.) vol. 14,9 (2021): 825-838. doi: https://doi.org/10.1158/1940-6207.CAPR-21-0114
Bernhardt SM, Borges VF, Schedin P. Vitamin D as a Potential Preventive Agent For Young Women's Breast Cancer. Cancer Prev Res (Phila). 2021 Sep;14(9):825-838. doi: 10.1158/1940-6207.CAPR-21-0114. Epub 2021 Jul 09. PMID: 34244152.
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Characterization of weaning-induced breast involution in women: implications for young women's breast cancer.

NPJ breast cancer

Jindal S, Narasimhan J, Borges VF, Schedin P.
PMID: 33083533
NPJ Breast Cancer. 2020 Oct 16;6:55. doi: 10.1038/s41523-020-00196-3. eCollection 2020.

In rodents, weaning-induced mammary gland involution supports increased mammary tumor incidence, growth, and progression to metastasis. Further, the protumor attributes of gland involution are COX-2 dependent and mitigated by short-duration non-steroidal anti-inflammatory drugs (NSAIDs), suggesting a potential prevention strategy....

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Jindal S, Narasimhan J, Borges VF, et al. Characterization of weaning-induced breast involution in women: implications for young women's breast cancer. NPJ Breast Cancer. 2020;6:55doi: 10.1038/s41523-020-00196-3.
Jindal, S., Narasimhan, J., Borges, V. F., & Schedin, P. (2020). Characterization of weaning-induced breast involution in women: implications for young women's breast cancer. NPJ breast cancer, 655. https://doi.org/10.1038/s41523-020-00196-3
Jindal, Sonali, et al. "Characterization of weaning-induced breast involution in women: implications for young women's breast cancer." NPJ breast cancer vol. 6 (2020): 55. doi: https://doi.org/10.1038/s41523-020-00196-3
Jindal S, Narasimhan J, Borges VF, Schedin P. Characterization of weaning-induced breast involution in women: implications for young women's breast cancer. NPJ Breast Cancer. 2020 Oct 16;6:55. doi: 10.1038/s41523-020-00196-3. eCollection 2020. PMID: 33083533; PMCID: PMC7568540.
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Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes.

Nature communications

Jindal S, Pennock ND, Sun D, Horton W, Ozaki MK, Narasimhan J, Bartlett AQ, Weinmann S, Goss PE, Borges VF, Xia Z, Schedin P.
PMID: 34732713
Nat Commun. 2021 Nov 03;12(1):6341. doi: 10.1038/s41467-021-26505-3.

Young women's breast cancer (YWBC) has poor prognosis and known interactions with parity. Women diagnosed within 5-10 years of childbirth, defined as postpartum breast cancer (PPBC), have poorer prognosis compared to age, stage, and biologic subtype-matched nulliparous patients. Genomic...

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Jindal S, Pennock ND, Sun D, et al. Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes. Nat Commun. 2021;12(1):6341doi: 10.1038/s41467-021-26505-3.
Jindal, S., Pennock, N. D., Sun, D., Horton, W., Ozaki, M. K., Narasimhan, J., Bartlett, A. Q., Weinmann, S., Goss, P. E., Borges, V. F., Xia, Z., & Schedin, P. (2021). Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes. Nature communications, 12(1), 6341. https://doi.org/10.1038/s41467-021-26505-3
Jindal, Sonali, et al. "Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes." Nature communications vol. 12,1 (2021): 6341. doi: https://doi.org/10.1038/s41467-021-26505-3
Jindal S, Pennock ND, Sun D, Horton W, Ozaki MK, Narasimhan J, Bartlett AQ, Weinmann S, Goss PE, Borges VF, Xia Z, Schedin P. Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes. Nat Commun. 2021 Nov 03;12(1):6341. doi: 10.1038/s41467-021-26505-3. PMID: 34732713; PMCID: PMC8566602.
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S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue.

NPJ breast cancer

Jindal S, Pennock ND, Klug A, Narasimhan J, Calhoun A, Roberts MR, Tamimi RM, Eliassen AH, Weinmann S, Borges VF, Schedin P.
PMID: 33298921
NPJ Breast Cancer. 2020 Nov 24;6(1):62. doi: 10.1038/s41523-020-00204-6.

Immunohistochemical (IHC) staining in breast cancer shows both gain and loss of COX2 expression with disease risk and progression. We investigated four common COX2 antibody clones and found high specificity for purified human COX2 for three clones; however, recognition...

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Jindal S, Pennock ND, Klug A, et al. S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue. NPJ Breast Cancer. 2020;6(1):62doi: 10.1038/s41523-020-00204-6.
Jindal, S., Pennock, N. D., Klug, A., Narasimhan, J., Calhoun, A., Roberts, M. R., Tamimi, R. M., Eliassen, A. H., Weinmann, S., Borges, V. F., & Schedin, P. (2020). S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue. NPJ breast cancer, 6(1), 62. https://doi.org/10.1038/s41523-020-00204-6
Jindal, Sonali, et al. "S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue." NPJ breast cancer vol. 6,1 (2020): 62. doi: https://doi.org/10.1038/s41523-020-00204-6
Jindal S, Pennock ND, Klug A, Narasimhan J, Calhoun A, Roberts MR, Tamimi RM, Eliassen AH, Weinmann S, Borges VF, Schedin P. S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue. NPJ Breast Cancer. 2020 Nov 24;6(1):62. doi: 10.1038/s41523-020-00204-6. PMID: 33298921; PMCID: PMC7686348.
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A METHOD FOR QUANTIFICATION OF CALPONIN EXPRESSION IN MYOEPITHELIAL CELLS IN IMMUNOHISTOCHEMICAL IMAGES OF DUCTAL CARCINOMA IN SITU.

Proceedings. IEEE International Symposium on Biomedical Imaging

Gray E, Mitchell E, Jindal S, Schedin P, Chang YH.
PMID: 30364524
Proc IEEE Int Symp Biomed Imaging. 2018 Apr;2018:796-799. doi: 10.1109/ISBI.2018.8363692. Epub 2018 May 24.

Ductal carcinoma in situ (DCIS) is breast cancer confined within mammary ducts, surrounded by an intact myoepithelial cell layer that prevents local invasion. A DCIS diagnosis confers increased lifetime risk of developing invasive breast cancer (IBC) and results in...

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Gray E, Mitchell E, Jindal S, et al. A METHOD FOR QUANTIFICATION OF CALPONIN EXPRESSION IN MYOEPITHELIAL CELLS IN IMMUNOHISTOCHEMICAL IMAGES OF DUCTAL CARCINOMA IN SITU. Proc IEEE Int Symp Biomed Imaging. 2018;2018:796-799doi: 10.1109/ISBI.2018.8363692.
Gray, E., Mitchell, E., Jindal, S., Schedin, P., & Chang, Y. H. (2018). A METHOD FOR QUANTIFICATION OF CALPONIN EXPRESSION IN MYOEPITHELIAL CELLS IN IMMUNOHISTOCHEMICAL IMAGES OF DUCTAL CARCINOMA IN SITU. Proceedings. IEEE International Symposium on Biomedical Imaging, 2018796-799. https://doi.org/10.1109/ISBI.2018.8363692
Gray, Elliot, et al. "A METHOD FOR QUANTIFICATION OF CALPONIN EXPRESSION IN MYOEPITHELIAL CELLS IN IMMUNOHISTOCHEMICAL IMAGES OF DUCTAL CARCINOMA IN SITU." Proceedings. IEEE International Symposium on Biomedical Imaging vol. 2018 (2018): 796-799. doi: https://doi.org/10.1109/ISBI.2018.8363692
Gray E, Mitchell E, Jindal S, Schedin P, Chang YH. A METHOD FOR QUANTIFICATION OF CALPONIN EXPRESSION IN MYOEPITHELIAL CELLS IN IMMUNOHISTOCHEMICAL IMAGES OF DUCTAL CARCINOMA IN SITU. Proc IEEE Int Symp Biomed Imaging. 2018 Apr;2018:796-799. doi: 10.1109/ISBI.2018.8363692. Epub 2018 May 24. PMID: 30364524; PMCID: PMC6196724.
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Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox.

Journal of clinical medicine

Guo Q, Betts C, Pennock N, Mitchell E, Schedin P.
PMID: 28098775
J Clin Med. 2017 Jan 13;6(1). doi: 10.3390/jcm6010010.

Transforming Growth Factor-β (TGF-β) signaling in cancer has been termed the "TGF-β paradox", acting as both a tumor suppresser and promoter. The complexity of TGF-β signaling within the tumor is context dependent, and greatly impacted by cellular crosstalk between...

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Guo Q, Betts C, Pennock N, et al. Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox. J Clin Med. 2017;6(1)doi: 10.3390/jcm6010010.
Guo, Q., Betts, C., Pennock, N., Mitchell, E., & Schedin, P. (2017). Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox. Journal of clinical medicine, 6(1), . https://doi.org/10.3390/jcm6010010
Guo, Qiuchen, et al. "Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox." Journal of clinical medicine vol. 6,1 (2017). doi: https://doi.org/10.3390/jcm6010010
Guo Q, Betts C, Pennock N, Mitchell E, Schedin P. Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox. J Clin Med. 2017 Jan 13;6(1). doi: 10.3390/jcm6010010. PMID: 28098775; PMCID: PMC5294963.
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Showing 1 to 6 of 6 entries