Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 8 of 8 entries
Sorted by: Best Match Show Resources per page
Abnormal Excitability of Oblique Dendrites Implicated in Early Alzheimer's: A Computational Study.

Frontiers in neural circuits

Morse TM, Carnevale NT, Mutalik PG, Migliore M, Shepherd GM.
PMID: 20725509
Front Neural Circuits. 2010 May 31;4. doi: 10.3389/fncir.2010.00016. eCollection 2010.

The integrative properties of cortical pyramidal dendrites are essential to the neural basis of cognitive function, but the impact of amyloid beta protein (abeta) on these properties in early Alzheimer's is poorly understood. In animal models, electrophysiological studies of...

Functional roles of distributed synaptic clusters in the mitral-granule cell network of the olfactory bulb.

Frontiers in integrative neuroscience

Migliore M, Hines ML, McTavish TS, Shepherd GM.
PMID: 21258619
Front Integr Neurosci. 2010 Sep 20;4:122. doi: 10.3389/fnint.2010.00122. eCollection 2010.

Odors are encoded in spatio-temporal patterns within the olfactory bulb, but the mechanisms of odor recognition and discrimination are poorly understood. It is reasonable to postulate that the olfactory code is sculpted by lateral and feedforward inhibition mediated by...

Lateral Connectivity in the Olfactory Bulb is Sparse and Segregated.

Frontiers in neural circuits

Kim DH, Phillips ME, Chang AY, Patel HK, Nguyen KT, Willhite DC.
PMID: 21559072
Front Neural Circuits. 2011 Apr 25;5:5. doi: 10.3389/fncir.2011.00005. eCollection 2011.

Lateral connections in the olfactory bulb were previously thought to be organized for center-surround inhibition. However, recent anatomical and physiological studies showed sparse and distributed interactions of inhibitory granule cells (GCs) which tended to be organized in columnar clusters....

Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium.

Frontiers in cellular neuroscience

Sadler E, Ryals MM, May LA, Martin D, Welsh N, Boger ET, Morell RJ, Hertzano R, Cunningham LL.
PMID: 32528249
Front Cell Neurosci. 2020 May 15;14:123. doi: 10.3389/fncel.2020.00123. eCollection 2020.

Sensory epithelia of the inner ear contain mechanosensory hair cells (HCs) and glia-like supporting cells (SCs), both of which are required for hearing and balance functions. Each of these cell types has unique responses to ototoxic and cytoprotective stimuli....

Center-surround vs. distance-independent lateral connectivity in the olfactory bulb.

Frontiers in neural circuits

Kim DH, Chang AY, McTavish TS, Patel HK, Willhite DC.
PMID: 22666190
Front Neural Circuits. 2012 May 31;6:34. doi: 10.3389/fncir.2012.00034. eCollection 2012.

Lateral neuronal interactions are known to play important roles in sensory information processing. A center-on surround-off local circuit arrangement has been shown to play a role in mediating contrast enhancement in the visual, auditory, and somatosensory systems. The lateral...

Learning mechanism for column formation in the olfactory bulb.

Frontiers in integrative neuroscience

Migliore M, Inzirillo C, Shepherd GM.
PMID: 18958240
Front Integr Neurosci. 2007 Dec 30;1:12. doi: 10.3389/neuro.07.012.2007. eCollection 2007.

Sensory discrimination requires distributed arrays of processing units. In the olfactory bulb, the processing units for odor discrimination are believed to involve dendrodendritic synaptic interactions between mitral and granule cells. There is increasing anatomical evidence that these cells are...

An ontological approach to describing neurons and their relationships.

Frontiers in neuroinformatics

Hamilton DJ, Shepherd GM, Martone ME, Ascoli GA.
PMID: 22557965
Front Neuroinform. 2012 Apr 27;6:15. doi: 10.3389/fninf.2012.00015. eCollection 2012.

The advancement of neuroscience, perhaps one of the most information rich disciplines of all the life sciences, requires basic frameworks for organizing the vast amounts of data generated by the research community to promote novel insights and integrated understanding....

Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea.

Frontiers in molecular neuroscience

Hoa M, Olszewski R, Li X, Taukulis I, Gu S, DeTorres A, Lopez IA, Linthicum FH, Ishiyama A, Martin D, Morell RJ, Kelley MW.
PMID: 32116546
Front Mol Neurosci. 2020 Feb 05;13:13. doi: 10.3389/fnmol.2020.00013. eCollection 2020.

Hearing loss is a problem that impacts a significant proportion of the adult population. Cochlear hair cell (HC) loss due to loud noise, chemotherapy and aging is the major underlying cause. A significant proportion of these individuals are dissatisfied...

Showing 1 to 8 of 8 entries