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Regional Colonic Transit Pattern Does Not Conclusively Identify Evacuation Disorders in Constipated Patients with Delayed Colonic Transit.

Journal of neurogastroenterology and motility

Park SY, Burton D, Busciglio I, Eckert D, Camilleri M.
PMID: 27667753
J Neurogastroenterol Motil. 2017 Jan 30;23(1):92-100. doi: 10.5056/jnm16066.

BACKGROUND/AIMS: After exclusion of structural diseases, chronic constipation may be associated with normal or slow transit or rectal evacuation disorders. We evaluated: (1) clinical features and anorectal function, (2) difference of regional colonic transit according to the presence or...

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Park SY, Burton D, Busciglio I, et al. Regional Colonic Transit Pattern Does Not Conclusively Identify Evacuation Disorders in Constipated Patients with Delayed Colonic Transit. J Neurogastroenterol Motil. 2017;23(1):92-100doi: 10.5056/jnm16066.
Park, S. Y., Burton, D., Busciglio, I., Eckert, D., & Camilleri, M. (2017). Regional Colonic Transit Pattern Does Not Conclusively Identify Evacuation Disorders in Constipated Patients with Delayed Colonic Transit. Journal of neurogastroenterology and motility, 23(1), 92-100. https://doi.org/10.5056/jnm16066
Park, Seon-Young, et al. "Regional Colonic Transit Pattern Does Not Conclusively Identify Evacuation Disorders in Constipated Patients with Delayed Colonic Transit." Journal of neurogastroenterology and motility vol. 23,1 (2017): 92-100. doi: https://doi.org/10.5056/jnm16066
Park SY, Burton D, Busciglio I, Eckert D, Camilleri M. Regional Colonic Transit Pattern Does Not Conclusively Identify Evacuation Disorders in Constipated Patients with Delayed Colonic Transit. J Neurogastroenterol Motil. 2017 Jan 30;23(1):92-100. doi: 10.5056/jnm16066. PMID: 27667753; PMCID: PMC5216639.
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Elobixibat and its potential role in chronic idiopathic constipation.

Therapeutic advances in gastroenterology

Acosta A, Camilleri M.
PMID: 25057297
Therap Adv Gastroenterol. 2014 Jul;7(4):167-75. doi: 10.1177/1756283X14528269.

Chronic idiopathic constipation is highly prevalent among adults. Bile acids (BAs) and the enterohepatic BA circulation modulate colonic secretion and motility that affect transit. BAs in the colon have a dual action as osmotic and stimulant agents. Newer agents,...

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Acosta A, Camilleri M. Elobixibat and its potential role in chronic idiopathic constipation. Therap Adv Gastroenterol. 2014;7(4):167-75doi: 10.1177/1756283X14528269.
Acosta, A., & Camilleri, M. (2014). Elobixibat and its potential role in chronic idiopathic constipation. Therapeutic advances in gastroenterology, 7(4), 167-75. https://doi.org/10.1177/1756283X14528269
Acosta, Andres, and Camilleri, Michael. "Elobixibat and its potential role in chronic idiopathic constipation." Therapeutic advances in gastroenterology vol. 7,4 (2014): 167-75. doi: https://doi.org/10.1177/1756283X14528269
Acosta A, Camilleri M. Elobixibat and its potential role in chronic idiopathic constipation. Therap Adv Gastroenterol. 2014 Jul;7(4):167-75. doi: 10.1177/1756283X14528269. PMID: 25057297; PMCID: PMC4107709.
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Opioid-induced constipation: rationale for the role of norbuprenorphine in buprenorphine-treated individuals.

Substance abuse and rehabilitation

Webster LR, Camilleri M, Finn A.
PMID: 27366109
Subst Abuse Rehabil. 2016 Jun 14;7:81-6. doi: 10.2147/SAR.S100998. eCollection 2016.

Buprenorphine and buprenorphine-naloxone fixed combinations are effective for managing patients with opioid dependence, but constipation is one of the most common side effects. Evidence indicates that the rate of constipation is lower when patients are switched from sublingual buprenorphine-naloxone...

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Webster LR, Camilleri M, Finn A. Opioid-induced constipation: rationale for the role of norbuprenorphine in buprenorphine-treated individuals. Subst Abuse Rehabil. 2016;7:81-6doi: 10.2147/SAR.S100998.
Webster, L. R., Camilleri, M., & Finn, A. (2016). Opioid-induced constipation: rationale for the role of norbuprenorphine in buprenorphine-treated individuals. Substance abuse and rehabilitation, 781-6. https://doi.org/10.2147/SAR.S100998
Webster, Lynn R, et al. "Opioid-induced constipation: rationale for the role of norbuprenorphine in buprenorphine-treated individuals." Substance abuse and rehabilitation vol. 7 (2016): 81-6. doi: https://doi.org/10.2147/SAR.S100998
Webster LR, Camilleri M, Finn A. Opioid-induced constipation: rationale for the role of norbuprenorphine in buprenorphine-treated individuals. Subst Abuse Rehabil. 2016 Jun 14;7:81-6. doi: 10.2147/SAR.S100998. eCollection 2016. PMID: 27366109; PMCID: PMC4913538.
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Irritable bowel syndrome: how useful is the term and the 'diagnosis'?.

Therapeutic advances in gastroenterology

Camilleri M.
PMID: 23152731
Therap Adv Gastroenterol. 2012 Nov;5(6):381-6. doi: 10.1177/1756283X12442223.

No abstract available.

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Camilleri M. Irritable bowel syndrome: how useful is the term and the 'diagnosis'?. Therap Adv Gastroenterol. 2012;5(6):381-6doi: 10.1177/1756283X12442223.
Camilleri, M. (2012). Irritable bowel syndrome: how useful is the term and the 'diagnosis'?. Therapeutic advances in gastroenterology, 5(6), 381-6. https://doi.org/10.1177/1756283X12442223
Camilleri, Michael. "Irritable bowel syndrome: how useful is the term and the 'diagnosis'?." Therapeutic advances in gastroenterology vol. 5,6 (2012): 381-6. doi: https://doi.org/10.1177/1756283X12442223
Camilleri M. Irritable bowel syndrome: how useful is the term and the 'diagnosis'?. Therap Adv Gastroenterol. 2012 Nov;5(6):381-6. doi: 10.1177/1756283X12442223. PMID: 23152731; PMCID: PMC3491678.
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Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Nature genetics

Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M.
PMID: 34741163
Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05.

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a...

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Eijsbouts C, Zheng T, Kennedy NA, et al. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021;53(11):1543-1552doi: 10.1038/s41588-021-00950-8.
Eijsbouts, C., Zheng, T., Kennedy, N. A., Bonfiglio, F., Anderson, C. A., Moutsianas, L., Holliday, J., Shi, J., Shringarpure, S., Voda, A. I., Farrugia, G., Franke, A., Hübenthal, M., Abecasis, G., Zawistowski, M., Skogholt, A. H., Ness-Jensen, E., Hveem, K., Esko, T., Teder-Laving, M., Zhernakova, A., Camilleri, M., Boeckxstaens, G., Whorwell, P. J., Spiller, R., McVean, G., D'Amato, M., Jostins, L., & Parkes, M. (2021). Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nature genetics, 53(11), 1543-1552. https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts, Chris, et al. "Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders." Nature genetics vol. 53,11 (2021): 1543-1552. doi: https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05. PMID: 34741163; PMCID: PMC8571093.
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Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Nature genetics

Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M.
PMID: 34741163
Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05.

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptibility genes could highlight the underlying pathophysiological mechanisms. We designed a digestive health questionnaire for UK Biobank and combined identified cases with IBS with independent cohorts. We conducted a...

Cite
Eijsbouts C, Zheng T, Kennedy NA, et al. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021;53(11):1543-1552doi: 10.1038/s41588-021-00950-8.
Eijsbouts, C., Zheng, T., Kennedy, N. A., Bonfiglio, F., Anderson, C. A., Moutsianas, L., Holliday, J., Shi, J., Shringarpure, S., Voda, A. I., Farrugia, G., Franke, A., Hübenthal, M., Abecasis, G., Zawistowski, M., Skogholt, A. H., Ness-Jensen, E., Hveem, K., Esko, T., Teder-Laving, M., Zhernakova, A., Camilleri, M., Boeckxstaens, G., Whorwell, P. J., Spiller, R., McVean, G., D'Amato, M., Jostins, L., & Parkes, M. (2021). Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nature genetics, 53(11), 1543-1552. https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts, Chris, et al. "Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders." Nature genetics vol. 53,11 (2021): 1543-1552. doi: https://doi.org/10.1038/s41588-021-00950-8
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S, Voda AI, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders. Nat Genet. 2021 Nov;53(11):1543-1552. doi: 10.1038/s41588-021-00950-8. Epub 2021 Nov 05. PMID: 34741163; PMCID: PMC8571093.
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Novel Association of Rectal Evacuation Disorder and Rumination Syndrome: Diagnosis, Co-morbidities and Treatment.

United European gastroenterology journal

Vijayvargiya P, Iturrino J, Camilleri M, Shin A, Vazquez-Roque M, Katzka DA, Snuggerud JR, Seime RJ.
PMID: 24724013
United European Gastroenterol J. 2014 Feb 01;2(1):38-46. doi: 10.1177/2050640613518774.

BACKGROUND: Patients with disorders of gastrointestinal function may undergo unnecessary treatment if misdiagnosed as motility disorders.OBJECTIVE: To report on clinical features, medical, surgical and psychiatric co-morbidities, and prior treatments of a patient cohort diagnosed concurrently with non-psychogenic rumination syndrome...

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Vijayvargiya P, Iturrino J, Camilleri M, et al. Novel Association of Rectal Evacuation Disorder and Rumination Syndrome: Diagnosis, Co-morbidities and Treatment. United European Gastroenterol J. 2014;2(1):38-46doi: 10.1177/2050640613518774.
Vijayvargiya, P., Iturrino, J., Camilleri, M., Shin, A., Vazquez-Roque, M., Katzka, D. A., Snuggerud, J. R., & Seime, R. J. (2014). Novel Association of Rectal Evacuation Disorder and Rumination Syndrome: Diagnosis, Co-morbidities and Treatment. United European gastroenterology journal, 2(1), 38-46. https://doi.org/10.1177/2050640613518774
Vijayvargiya, Priya, et al. "Novel Association of Rectal Evacuation Disorder and Rumination Syndrome: Diagnosis, Co-morbidities and Treatment." United European gastroenterology journal vol. 2,1 (2014): 38-46. doi: https://doi.org/10.1177/2050640613518774
Vijayvargiya P, Iturrino J, Camilleri M, Shin A, Vazquez-Roque M, Katzka DA, Snuggerud JR, Seime RJ. Novel Association of Rectal Evacuation Disorder and Rumination Syndrome: Diagnosis, Co-morbidities and Treatment. United European Gastroenterol J. 2014 Feb 01;2(1):38-46. doi: 10.1177/2050640613518774. PMID: 24724013; PMCID: PMC3979495.
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Rifaximin, Microbiota Biology, and Hepatic Encephalopathy.

Clinical and translational gastroenterology

Peleman C, Camilleri M.
PMID: 27711069
Clin Transl Gastroenterol. 2016 Oct 06;7(10):e195. doi: 10.1038/ctg.2016.52.

Rifaximin is beneficial in the treatment of minimal hepatic encephalopathy (MHE). Kang et al. (Clin Transl Gastroenterol 7: e187; doi:10.1038/ctg.2016.44) investigated the effects of rifaximin in a mouse model of MHE-associated microbiota without concomitant liver disease. In addition to...

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Peleman C, Camilleri M. Rifaximin, Microbiota Biology, and Hepatic Encephalopathy. Clin Transl Gastroenterol. 2016;7(10):e195doi: 10.1038/ctg.2016.52.
Peleman, C., & Camilleri, M. (2016). Rifaximin, Microbiota Biology, and Hepatic Encephalopathy. Clinical and translational gastroenterology, 7(10), e195. https://doi.org/10.1038/ctg.2016.52
Peleman, Cedric, and Camilleri, Michael. "Rifaximin, Microbiota Biology, and Hepatic Encephalopathy." Clinical and translational gastroenterology vol. 7,10 (2016): e195. doi: https://doi.org/10.1038/ctg.2016.52
Peleman C, Camilleri M. Rifaximin, Microbiota Biology, and Hepatic Encephalopathy. Clin Transl Gastroenterol. 2016 Oct 06;7(10):e195. doi: 10.1038/ctg.2016.52. PMID: 27711069; PMCID: PMC5288587.
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Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunities.

Therapeutic advances in gastroenterology

Nelson AD, Camilleri M.
PMID: 26136838
Therap Adv Gastroenterol. 2015 Jul;8(4):206-20. doi: 10.1177/1756283X15578608.

With the recent introduction and approval of medications directed at the treatment of opioid induced constipation (OIC) in patients with nonmalignant pain, there is increased interest and understanding of the unmet need and opportunities to enhance patient management. The...

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Nelson AD, Camilleri M. Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunities. Therap Adv Gastroenterol. 2015;8(4):206-20doi: 10.1177/1756283X15578608.
Nelson, A. D., & Camilleri, M. (2015). Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunities. Therapeutic advances in gastroenterology, 8(4), 206-20. https://doi.org/10.1177/1756283X15578608
Nelson, Alfred D, and Camilleri, Michael. "Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunities." Therapeutic advances in gastroenterology vol. 8,4 (2015): 206-20. doi: https://doi.org/10.1177/1756283X15578608
Nelson AD, Camilleri M. Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunities. Therap Adv Gastroenterol. 2015 Jul;8(4):206-20. doi: 10.1177/1756283X15578608. PMID: 26136838; PMCID: PMC4480571.
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Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals.

Cellular and molecular gastroenterology and hepatology

Camilleri M, Linden DR.
PMID: 27648466
Cell Mol Gastroenterol Hepatol. 2016 Jul;2(4):412-428. doi: 10.1016/j.jcmgh.2016.04.003.

Accurately measuring the complex motor behaviors of the gastrointestinal tract has tremendous value for the understanding, diagnosis and treatment of digestive diseases. This review synthesizes the literature regarding current tests that are used in both humans and animals. There...

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Camilleri M, Linden DR. Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals. Cell Mol Gastroenterol Hepatol. 2016;2(4):412-428doi: 10.1016/j.jcmgh.2016.04.003.
Camilleri, M., & Linden, D. R. (2016). Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals. Cellular and molecular gastroenterology and hepatology, 2(4), 412-428. https://doi.org/10.1016/j.jcmgh.2016.04.003
Camilleri, Michael, and Linden, David R. "Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals." Cellular and molecular gastroenterology and hepatology vol. 2,4 (2016): 412-428. doi: https://doi.org/10.1016/j.jcmgh.2016.04.003
Camilleri M, Linden DR. Measurement of Gastrointestinal and Colonic Motor Functions in Humans and Animals. Cell Mol Gastroenterol Hepatol. 2016 Jul;2(4):412-428. doi: 10.1016/j.jcmgh.2016.04.003. PMID: 27648466; PMCID: PMC5026190.
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