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A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans.

Current opinion in immunology

Goswamy D, Irazoqui JE.
PMID: 32898751
Curr Opin Immunol. 2021 Feb;68:9-20. doi: 10.1016/j.coi.2020.08.002. Epub 2020 Sep 06.

During intestinal infection, microbes induce ROS by various mechanisms in C. elegans. ROS can have beneficial roles, acting as antimicrobials and as signaling molecules that activate cytoprotective pathways. Failure to maintain appropriate levels of ROS causes oxidative stress and...

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Goswamy D, Irazoqui JE. A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans. Curr Opin Immunol. 2020;68:9-20doi: 10.1016/j.coi.2020.08.002.
Goswamy, D., & Irazoqui, J. E. (2021). A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans. Current opinion in immunology, 689-20. https://doi.org/10.1016/j.coi.2020.08.002
Goswamy, Debanjan, and Irazoqui, Javier E. "A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans." Current opinion in immunology vol. 68 (2021): 9-20. doi: https://doi.org/10.1016/j.coi.2020.08.002
Goswamy D, Irazoqui JE. A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans. Curr Opin Immunol. 2021 Feb;68:9-20. doi: 10.1016/j.coi.2020.08.002. Epub 2020 Sep 06. PMID: 32898751; PMCID: PMC7925333.
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A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS.

Autophagy

Najibi M, Honwad HH, Moreau JA, Becker SM, Irazoqui JE.
PMID: 33818279
Autophagy. 2021 Apr 13;1-18. doi: 10.1080/15548627.2021.1911548. Epub 2021 Apr 13.

Macrophage activation in the presence of bacterial cells and molecules entails complex programs of gene expression. How such triggers elicit specific gene expression programs is incompletely understood. We previously discovered that TFEB (transcription factor EB) is a key contributor...

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Najibi M, Honwad HH, Moreau JA, et al. A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS. Autophagy. 2021;1-18doi: 10.1080/15548627.2021.1911548.
Najibi, M., Honwad, H. H., Moreau, J. A., Becker, S. M., & Irazoqui, J. E. (2021). A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS. Autophagy, 1-18. https://doi.org/10.1080/15548627.2021.1911548
Najibi, Mehran, et al. "A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS." Autophagy vol. (2021): 1-18. doi: https://doi.org/10.1080/15548627.2021.1911548
Najibi M, Honwad HH, Moreau JA, Becker SM, Irazoqui JE. A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS. Autophagy. 2021 Apr 13;1-18. doi: 10.1080/15548627.2021.1911548. Epub 2021 Apr 13. PMID: 33818279.
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