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Endothelial Antioxidant-1: a Key Mediator of Copper-dependent Wound Healing in vivo.

Scientific reports

Das A, Sudhahar V, Chen GF, Kim HW, Youn SW, Finney L, Vogt S, Yang J, Kweon J, Surenkhuu B, Ushio-Fukai M, Fukai T.
PMID: 27666810
Sci Rep. 2016 Sep 26;6:33783. doi: 10.1038/srep33783.

Copper (Cu), an essential nutrient, promotes wound healing, however, target of Cu action and underlying mechanisms remain elusive. Cu chaperone Antioxidant-1 (Atox1) in the cytosol supplies Cu to the secretory enzymes such as lysyl oxidase (LOX), while Atox1 in...

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