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Showing 1 to 12 of 13 entries
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Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity.

Movement disorders : official journal of the Movement Disorder Society

Hengel H, Martus P, Faber J, Garcia-Moreno H, Solanky N, Giunti P, Klockgether T, Reetz K, van de Warrenburg BP, Pereira de Almeida L, Santana MM, Januário C, Silva P, Thieme A, Infante J, de Vries J, Lima M, Ferreira AF, Bushara K, Jacobi H, Onyike C, Schmahmann JD, Hübener-Schmid J, Synofzik M, Schöls L.
PMID: 34713931
Mov Disord. 2021 Oct 29; doi: 10.1002/mds.28844. Epub 2021 Oct 29.

BACKGROUND: Lifestyle could influence the course of hereditary ataxias, but representative data are missing.OBJECTIVE: The objective of this study was to characterize lifestyle in spinocerebellar ataxia type 3 (SCA3) and investigate possible associations with disease parameters.METHODS: In a prospective...

Across-vendor standardization of semi-LASER for single-voxel MRS at 3T.

NMR in biomedicine

Deelchand DK, Berrington A, Noeske R, Joers JM, Arani A, Gillen J, Schär M, Nielsen JF, Peltier S, Seraji-Bozorgzad N, Landheer K, Juchem C, Soher BJ, Noll DC, Kantarci K, Ratai EM, Mareci TH, Barker PB, Öz G.
PMID: 31854045
NMR Biomed. 2021 May;34(5):e4218. doi: 10.1002/nbm.4218. Epub 2019 Dec 18.

The semi-adiabatic localization by adiabatic selective refocusing (sLASER) sequence provides single-shot full intensity signal with clean localization and minimal chemical shift displacement error and was recommended by the international MRS Consensus Group as the preferred localization sequence at high-...

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts' consensus recommendations.

NMR in biomedicine

Lin A, Andronesi O, Bogner W, Choi IY, Coello E, Cudalbu C, Juchem C, Kemp GJ, Kreis R, Krššák M, Lee P, Maudsley AA, Meyerspeer M, Mlynarik V, Near J, Öz G, Peek AL, Puts NA, Ratai EM, Tkáč I, Mullins PG.
PMID: 33559967
NMR Biomed. 2021 May;34(5):e4484. doi: 10.1002/nbm.4484. Epub 2021 Feb 09.

The translation of MRS to clinical practice has been impeded by the lack of technical standardization. There are multiple methods of acquisition, post-processing, and analysis whose details greatly impact the interpretation of the results. These details are often not...

Advanced single voxel .

NMR in biomedicine

Öz G, Deelchand DK, Wijnen JP, Mlynárik V, Xin L, Mekle R, Noeske R, Scheenen TWJ, Tkáč I.
PMID: 31922301
NMR Biomed. 2020 Jan 10;e4236. doi: 10.1002/nbm.4236. Epub 2020 Jan 10.

Conventional proton MRS has been successfully utilized to noninvasively assess tissue biochemistry in conditions that result in large changes in metabolite levels. For more challenging applications, namely, in conditions which result in subtle metabolite changes, the limitations of vendor-provided...

Multimodal imaging in RBD - present and future.

Nature reviews. Neurology

Boeve BF, Kantarci K.
PMID: 30104745
Nat Rev Neurol. 2018 Oct;14(10):574-576. doi: 10.1038/s41582-018-0054-3.

No abstract available.

Preprocessing, analysis and quantification in single-voxel magnetic resonance spectroscopy: experts' consensus recommendations.

NMR in biomedicine

Near J, Harris AD, Juchem C, Kreis R, Marjańska M, Öz G, Slotboom J, Wilson M, Gasparovic C.
PMID: 32084297
NMR Biomed. 2021 May;34(5):e4257. doi: 10.1002/nbm.4257. Epub 2020 Feb 21.

Once an MRS dataset has been acquired, several important steps must be taken to obtain the desired metabolite concentration measures. First, the data must be preprocessed to prepare them for analysis. Next, the intensity of the metabolite signal(s) of...

Sensitivity of Volumetric Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy to Progression of Spinocerebellar Ataxia Type 1.

Movement disorders clinical practice

Deelchand DK, Joers JM, Ravishankar A, Lyu T, Emir UE, Hutter D, Gomez CM, Bushara KO, Lenglet C, Eberly LE, Öz G.
PMID: 31538089
Mov Disord Clin Pract. 2019 Jul 10;6(7):549-558. doi: 10.1002/mdc3.12804. eCollection 2019 Sep.

BACKGROUND: Spinocerebellar ataxia type 1 (SCA1) causes progressive degeneration of the cerebellum and brainstem. Volumetric magnetic resonance imaging (MRI) was shown to be more sensitive to disease progression than the most sensitive clinical measure, the Scale for the Assessment...

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts' consensus recommendations.

NMR in biomedicine

Lin A, Andronesi O, Bogner W, Choi IY, Coello E, Cudalbu C, Juchem C, Kemp GJ, Kreis R, Krššák M, Lee P, Maudsley AA, Meyerspeer M, Mlynarik V, Near J, Öz G, Peek AL, Puts NA, Ratai EM, Tkáč I, Mullins PG.
PMID: 33559967
NMR Biomed. 2021 May;34(5):e4484. doi: 10.1002/nbm.4484. Epub 2021 Feb 09.

The translation of MRS to clinical practice has been impeded by the lack of technical standardization. There are multiple methods of acquisition, post-processing, and analysis whose details greatly impact the interpretation of the results. These details are often not...

Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations.

NMR in biomedicine

Lanz B, Abaei A, Braissant O, Choi IY, Cudalbu C, Henry PG, Gruetter R, Kara F, Kantarci K, Lee P, Lutz NW, Marjańska M, Mlynárik V, Rasche V, Xin L, Valette J.
PMID: 33565219
NMR Biomed. 2020 Aug 26;e4325. doi: 10.1002/nbm.4325. Epub 2020 Aug 26.

In vivo MRS is a non-invasive measurement technique used not only in humans, but also in animal models using high-field magnets. MRS enables the measurement of metabolite concentrations as well as metabolic rates and their modifications in healthy animals...

Minimum Reporting Standards for in vivo Magnetic Resonance Spectroscopy (MRSinMRS): Experts' consensus recommendations.

NMR in biomedicine

Lin A, Andronesi O, Bogner W, Choi IY, Coello E, Cudalbu C, Juchem C, Kemp GJ, Kreis R, Krššák M, Lee P, Maudsley AA, Meyerspeer M, Mlynarik V, Near J, Öz G, Peek AL, Puts NA, Ratai EM, Tkáč I, Mullins PG.
PMID: 33559967
NMR Biomed. 2021 May;34(5):e4484. doi: 10.1002/nbm.4484. Epub 2021 Feb 09.

The translation of MRS to clinical practice has been impeded by the lack of technical standardization. There are multiple methods of acquisition, post-processing, and analysis whose details greatly impact the interpretation of the results. These details are often not...

Terminology and concepts for the characterization of in vivo MR spectroscopy methods and MR spectra: Background and experts' consensus recommendations.

NMR in biomedicine

Kreis R, Boer V, Choi IY, Cudalbu C, de Graaf RA, Gasparovic C, Heerschap A, Krššák M, Lanz B, Maudsley AA, Meyerspeer M, Near J, Öz G, Posse S, Slotboom J, Terpstra M, Tkáč I, Wilson M, Bogner W.
PMID: 32808407
NMR Biomed. 2020 Aug 17;e4347. doi: 10.1002/nbm.4347. Epub 2020 Aug 17.

With a 40-year history of use for in vivo studies, the terminology used to describe the methodology and results of magnetic resonance spectroscopy (MRS) has grown substantially and is not consistent in many aspects. Given the platform offered by...

Brainstem and striatal volume changes are detectable in under 1 year and predict motor decline in spinocerebellar ataxia type 1.

Brain communications

Koscik TR, Sloat L, van der Plas E, Joers JM, Deelchand DK, Lenglet C, Öz G, Nopoulos PC.
PMID: 33409488
Brain Commun. 2020 Dec 15;2(2):fcaa184. doi: 10.1093/braincomms/fcaa184. eCollection 2020.

Spinocerebellar ataxia type 1 is a progressive neurodegenerative, movement disorder. With potential therapies on the horizon, it is critical to identify biomarkers that (i) differentiate between unaffected and spinocerebellar ataxia Type 1-affected individuals; (ii) track disease progression; and (iii)...

Showing 1 to 12 of 13 entries