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The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis.

Non-coding RNA

Pinkney HR, Wright BM, Diermeier SD.
PMID: 33339309
Noncoding RNA. 2020 Dec 16;6(4). doi: 10.3390/ncrna6040049.

Long non-coding RNAs (lncRNAs) are a rapidly expanding field of research, with many new transcripts identified each year. However, only a small subset of lncRNAs has been characterized functionally thus far. To aid investigating the mechanisms of action by...

Functional Screening Techniques to Identify Long Non-Coding RNAs as Therapeutic Targets in Cancer.

Cancers

Lucere KM, O'Malley MMR, Diermeier SD.
PMID: 33317042
Cancers (Basel). 2020 Dec 09;12(12). doi: 10.3390/cancers12123695.

Recent technological advancements such as CRISPR/Cas-based systems enable multiplexed, high-throughput screening for new therapeutic targets in cancer. While numerous functional screens have been performed on protein-coding genes to date, long non-coding RNAs (lncRNAs) represent an emerging class of potential...

Circular RNAs: Potential Applications as Therapeutic Targets and Biomarkers in Breast Cancer.

Non-coding RNA

Sarkar D, Diermeier SD.
PMID: 33466455
Noncoding RNA. 2021 Jan 05;7(1). doi: 10.3390/ncrna7010002.

Circular RNAs (circRNAs) are a class of non-coding RNAs that form a covalently closed loop. A number of functions and mechanisms of action for circRNAs have been reported, including as miRNA sponge, exerting transcriptional and translational regulation, interacting with...

Showing 1 to 3 of 3 entries