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Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets.

Physiological reports

Sage SO, Pugh N, Farndale RW, Harper AG.
PMID: 24303163
Physiol Rep. 2013 Oct;1(5):e00085. doi: 10.1002/phy2.85. Epub 2013 Oct 11.

We have previously demonstrated that Na(+)/Ca(2+) exchangers (NCXs) potentiate Ca(2+) signaling evoked by thapsigargin in human platelets, via their ability to modulate the secretion of autocoids from dense granules. This link was confirmed in platelets stimulated with the physiological...

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