Frontiers in neurology

Ross AP, Ben-Zacharia A, Harris C, Smrtka J.
PMID: 23482896
Front Neurol. 2013 Mar 08;4:21. doi: 10.3389/fneur.2013.00021. eCollection 2013.

Relapses in multiple sclerosis (MS) are disruptive and frequently disabling for patients, and their treatment is often a challenge to clinicians. Despite progress in the understanding of the pathophysiology of MS and development of new treatments for long-term management...

Frontiers in endocrinology

Wang W, Guo DY, Lin YJ, Tao YX.
PMID: 31649620
Front Endocrinol (Lausanne). 2019 Oct 09;10:683. doi: 10.3389/fendo.2019.00683. eCollection 2019.

Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin receptors), are components of an ancient modulatory system. The clinical use of ACTH in the treatment of rheumatoid...

Frontiers in physiology

Chang M, Chen B, Shaffner J, Dworkin LD, Gong R.
PMID: 33716796
Front Physiol. 2021 Feb 24;12:651236. doi: 10.3389/fphys.2021.651236. eCollection 2021.

Melanocortin peptides, melanocortin receptors, melanocortin receptor accessory proteins, and endogenous antagonists of melanocortin receptors are the key components constituting the melanocortin hormone system, one of the most complex and important hormonal systems in our body. A plethora of evidence...