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Fusion protein EWS-FLI1 is incorporated into a protein granule in cells.

RNA (New York, N.Y.)

Ahmed NS, Harrell LM, Wieland DR, Lay MA, Thompson VF, Schwartz JC.
PMID: 34035145
RNA. 2021 May 25; doi: 10.1261/rna.078827.121. Epub 2021 May 25.

Ewing sarcoma is driven by fusion proteins containing a low complexity (LC) domain that is intrinsically disordered and a powerful transcriptional regulator. The most common fusion protein found in Ewing sarcoma, EWS-FLI1, takes its LC domain from the RNA-binding...

Showing 1 to 1 of 1 entries