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Showing 1 to 12 of 13 entries
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Admission vitamin D status is associated with discharge destination in critically ill surgical patients.

Annals of intensive care

Brook K, Camargo CA, Christopher KB, Quraishi SA.
PMID: 26380991
Ann Intensive Care. 2015 Dec;5(1):23. doi: 10.1186/s13613-015-0065-9. Epub 2015 Sep 17.

BACKGROUND: Discharge destination after critical illness is increasingly recognized as a valuable patient-centered outcome. Recently, vitamin D status has been shown to be associated with important outcomes such as length of stay (LOS) and mortality in intensive care unit...

Addition of 25-hydroxyvitamin D levels to the Deyo-Charlson Comorbidity Index improves 90-day mortality prediction in critically ill patients.

Journal of intensive care

Mahato B, Otero TM, Holland CA, Giguere PT, Bajwa EK, Camargo CA, Quraishi SA.
PMID: 27330812
J Intensive Care. 2016 Jun 17;4:40. doi: 10.1186/s40560-016-0165-0. eCollection 2016.

BACKGROUND: The Deyo-Charlson Comorbidity Index (DCCI) has low predictive value in the intensive care unit (ICU). Our goal was to determine whether addition of 25-hydroxyvitamin D (25OHD) levels to the DCCI improved 90-day mortality prediction in critically ill patients.METHODS:...

Association Between Race and Ethnicity with Intraoperative Analgesic Administration and Initial Recovery Room Pain Scores in Pediatric Patients: a Single-Center Study of 21,229 Surgeries.

Journal of racial and ethnic health disparities

Jette CG, Rosenbloom JM, Wang E, De Souza E, Anderson TA.
PMID: 32621098
J Racial Ethn Health Disparities. 2021 Jun;8(3):547-558. doi: 10.1007/s40615-020-00811-w. Epub 2020 Jul 03.

INTRODUCTION: Perioperative pain may have deleterious effects for all patients. We aim to examine disparities in pain management for children in the perioperative period to understand whether any racial and ethnic groups are at increased risk of poor pain...

Circadian disturbances in Alzheimer's disease progression: a prospective observational cohort study of community-based older adults.

The Lancet. Healthy longevity

Li P, Gao L, Gaba A, Yu L, Cui L, Fan W, Lim ASP, Bennett DA, Buchman AS, Hu K.
PMID: 34179863
Lancet Healthy Longev. 2020 Dec;1(3):e96-e105. doi: 10.1016/s2666-7568(20)30015-5. Epub 2020 Nov 12.

BACKGROUND: Circadian disturbances are commonly seen in people with Alzheimer's disease and have been reported in individuals without symptoms of dementia but with Alzheimer's pathology. We aimed to assess the temporal relationship between circadian disturbances and Alzheimer's progression.METHODS: We...

Fragmentation of Rest/Activity Patterns in Community-Based Elderly Individuals Predicts Incident Heart Failure.

Nature and science of sleep

Gao L, Lim ASP, Wong PM, Gaba A, Cui L, Yu L, Buchman AS, Bennett DA, Hu K, Li P.
PMID: 32581616
Nat Sci Sleep. 2020 May 27;12:299-307. doi: 10.2147/NSS.S253757. eCollection 2020.

STUDY OBJECTIVES: Heart failure has previously been linked to sleep disorders that are often associated with frequent disturbances to human rest/activity patterns. We tested whether fragmentation of sustained rest/activity patterns derived from actigraphic recordings at baseline predicts incident heart...

Liver damage and systemic inflammatory responses are exacerbated by the genetic deletion of CD39 in total hepatic ischemia.

Purinergic signalling

Sun X, Imai M, Nowak-Machen M, Guckelberger O, Enjyoji K, Wu Y, Khalpey Z, Berberat P, Munasinghe J, Robson SC.
PMID: 21656186
Purinergic Signal. 2011 Dec;7(4):427-34. doi: 10.1007/s11302-011-9239-6. Epub 2011 Jun 09.

Liver ischemia reperfusion injury is associated with both local damage to the hepatic vasculature and systemic inflammatory responses. CD39 is the dominant vascular endothelial cell ectonucleotidase and rapidly hydrolyses both adenosine triphosphate (ATP) and adenosine diphosphate to adenosine monophosphate....

In Reply.

Anesthesiology

Nanji KC, Bates DW.
PMID: 27433765
Anesthesiology. 2016 Aug;125(2):432-7. doi: 10.1097/ALN.0000000000001188.

No abstract available.

Clinical Research Redirection and Optimization During a Pandemic.

Anesthesiology clinics

Santos LC, Low YH, Inozemtsev K, Nagrebetsky A.
PMID: 34024438
Anesthesiol Clin. 2021 Jun;39(2):379-388. doi: 10.1016/j.anclin.2021.03.004.

The COVID-19 pandemic has seen many hurdles to crucial research processes, in particular those that depend on personnel interactions, in providing safeguards against the incipient infectious disease. At the same time, there was a rapid redirection of research, driven...

The Association of Vitamin D Status and Pre-operative Physical Activity in Patients with Hip or Knee Osteoarthritis.

Journal of restorative medicine

Jacob EA, Blum L, Bedair HS, Freiberg AA, Quraishi SA.
PMID: 30505632
J Restor Med. 2015 Dec;4(1):3-10. doi: 10.14200/jrm.2015.4.0101.

BACKGROUND: Vitamin D is important for musculoskeletal health and may have significant implications for maintaining physical activity in elderly patients. Our goal was to investigate whether serum 25-hydroxyvitamin D (25OHD) levels are associated with pre-operative physical activity in patients...

Clinical implications of the transversus abdominis plane block in adults.

Anesthesiology research and practice

Young MJ, Gorlin AW, Modest VE, Quraishi SA.
PMID: 22312327
Anesthesiol Res Pract. 2012;2012:731645. doi: 10.1155/2012/731645. Epub 2012 Jan 19.

The transversus abdominis plane (TAP) block is a relatively new regional anesthesia technique that provides analgesia to the parietal peritoneum as well as the skin and muscles of the anterior abdominal wall. It has a high margin of safety...

Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19.

bioRxiv : the preprint server for biology

Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N.
PMID: 32908980
bioRxiv. 2020 Sep 02; doi: 10.1101/2020.09.02.280180.

A recent estimate suggests that one in five deaths globally are associated with sepsis

Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia.

Proceedings of the National Academy of Sciences of the United States of America

Taylor NE, Van Dort CJ, Kenny JD, Pei J, Guidera JA, Vlasov KY, Lee JT, Boyden ES, Brown EN, Solt K.
PMID: 27791160
Proc Natl Acad Sci U S A. 2016 Nov 08;113(45):12826-12831. doi: 10.1073/pnas.1614340113. Epub 2016 Oct 24.

Dopamine (DA) promotes wakefulness, and DA transporter inhibitors such as dextroamphetamine and methylphenidate are effective for increasing arousal and inducing reanimation, or active emergence from general anesthesia. DA neurons in the ventral tegmental area (VTA) are involved in reward...

Showing 1 to 12 of 13 entries