J Racial Ethn Health Disparities. 2021 Jun;8(3):547-558. doi: 10.1007/s40615-020-00811-w. Epub 2020 Jul 03.
Association Between Race and Ethnicity with Intraoperative Analgesic Administration and Initial Recovery Room Pain Scores in Pediatric Patients: a Single-Center Study of 21,229 Surgeries.
Journal of racial and ethnic health disparities
Christine G Jette, Julia M Rosenbloom, Ellen Wang, Elizabeth De Souza, T Anthony Anderson
Affiliations
Affiliations
- Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, USA.
- Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
- Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, USA. [email protected].
PMID: 32621098
PMCID: PMC8629166 DOI: 10.1007/s40615-020-00811-w
Abstract
INTRODUCTION: Perioperative pain may have deleterious effects for all patients. We aim to examine disparities in pain management for children in the perioperative period to understand whether any racial and ethnic groups are at increased risk of poor pain control.
METHODS: Medical records from children ≤ 18 years of age who underwent surgery from May 2014 to May 2018 were reviewed. The primary outcome was total intraoperative morphine equivalents. The secondary outcomes were intraoperative non-opioid analgesic administration and first conscious pain score. The exposure was race and ethnicity. The associations of race and ethnicity with outcomes of interest were modeled using linear or logistic regression, adjusted for preselected confounders and covariates. Bonferroni corrections were made for multiple comparisons.
RESULTS: A total of 21,229 anesthetics were included in analyses. In the adjusted analysis, no racial and ethnic group received significantly more or less opioids intraoperatively than non-Hispanic (NH) whites. Asians, Hispanics, and Pacific Islanders were estimated to have significantly lower odds of receiving non-opioid analgesics than NH whites: odds ratio (OR) = 0.83 (95% confidence interval (CI): 0.70, 0.97); OR = 0.84 (95% CI: 0.74, 0.97), and OR = 0.53 (95% CI: 0.33, 0.84) respectively. Asians were estimated to have significantly lower odds of reporting moderate-to-severe pain on awakening than NH whites: OR = 0.80 (95% CI: 0.66, 0.99).
CONCLUSIONS: Although children of all races and ethnicities investigated received similar total intraoperative opioid doses, some were less likely to receive non-opioid analgesics intraoperatively. Asians were less likely to report moderate-severe pain upon awakening. Further investigation may delineate how these differences lead to disparate patient outcomes and are influenced by patient, provider, and system factors.
Keywords: Healthcare disparities; Pediatric anesthesia; Perioperative analgesia; Race and ethnicity
References
- Can J Anaesth. 1998 Jul;45(7):612-9 - PubMed
- Hosp Pediatr. 2017 Jun;7(6):313-319 - PubMed
- Anesth Analg. 1998 Oct;87(4):816-26 - PubMed
- J Dev Behav Pediatr. 1984 Oct;5(5):246-50 - PubMed
- J Clin Anesth. 2004 May;16(3):200-6 - PubMed
- Behav Res Methods. 2009 Nov;41(4):1149-60 - PubMed
- Anesth Analg. 2016 Feb;122(2):472-9 - PubMed
- Br J Anaesth. 2018 May;120(5):1090-1102 - PubMed
- Otolaryngol Head Neck Surg. 2006 Feb;134(2):181-6 - PubMed
- J Clin Anesth. 2006 Aug;18(5):328-33 - PubMed
- J Bone Joint Surg Am. 2017 Aug 2;99(15):1247-1252 - PubMed
- Semin Perinatol. 2017 Aug;41(5):293-298 - PubMed
- Curr Opin Anaesthesiol. 2013 Aug;26(4):420-7 - PubMed
- Pain Med. 2010 Dec;11(12):1859-71 - PubMed
- Pediatrics. 2010 Jun;125(6):e1372-8 - PubMed
- Public Health Rep. 2003 Jul-Aug;118(4):293-302 - PubMed
- J Pain Res. 2017 Sep 25;10:2287-2298 - PubMed
- Arch Pediatr Adolesc Med. 1998 Feb;152(2):147-9 - PubMed
- J Health Care Poor Underserved. 2010 Feb;21(1):229-36 - PubMed
- Br J Anaesth. 2012 Oct;109(4):616-22 - PubMed
- Am J Public Health. 2018 Mar;108(3):e1-e11 - PubMed
- Paediatr Anaesth. 2013 Feb;23(2):170-9 - PubMed
- PLoS One. 2014 Jun 30;9(6):e101259 - PubMed
- Pain Ther. 2016 Jun;5(1):63-80 - PubMed
- Pediatrics. 2014 Sep;134(3):634-41 - PubMed
- Lancet. 2006 May 13;367(9522):1618-25 - PubMed
- Cochrane Database Syst Rev. 2014 Jan 28;(1):CD009633 - PubMed
- Anesthesiology. 2015 Mar;122(3):659-65 - PubMed
- Pain Med. 2012 Apr;13(4):522-40 - PubMed
- Br J Anaesth. 2014 Jun;112(6):991-1004 - PubMed
- Anesthesiology. 2007 Jan;106(1):19-25; discussion 6-8 - PubMed
- Natl Health Stat Report. 2017 Feb;(102):1-15 - PubMed
- Front Psychol. 2016 Sep 30;7:1466 - PubMed
- Br J Anaesth. 2011 Oct;107(4):619-26 - PubMed
- Paediatr Anaesth. 2017 Nov;27(11):1142-1147 - PubMed
- Cancer Epidemiol Biomarkers Prev. 2018 Aug;27(8):917-927 - PubMed
- Pediatrics. 2006 Aug;118(2):651-8 - PubMed
- Pediatrics. 2019 Apr;143(4): - PubMed
- Paediatr Anaesth. 2018 Jun;28(6):482-492 - PubMed
- Acta Anaesthesiol Scand. 2008 Jul;52(6):821-8 - PubMed
- J Pediatr Surg. 2016 Apr;51(4):612-6 - PubMed
- Paediatr Anaesth. 2017 Jul;27(7):760-767 - PubMed
- Paediatr Anaesth. 2012 Jul;22(7):669-75 - PubMed
- Br J Anaesth. 2000 Oct;85(4):533-40 - PubMed
- Pain. 2017 Feb;158(2):194-211 - PubMed
- Paediatr Anaesth. 2011 Jun;21(6):636-52 - PubMed
- Hosp Pediatr. 2014 Jan;4(1):23-30 - PubMed
- Pain Physician. 2017 Sep;20(6):E755-E796 - PubMed
- Anesth Analg. 2012 Feb;114(2):393-406 - PubMed
- Natl Health Stat Report. 2013 Feb 11;(63):1-3 - PubMed
- Pain. 2013 Jan;154(1):154-159 - PubMed
- Pain Res Manag. 2014 Jan-Feb;19(1):e24-30 - PubMed
- Anesth Analg. 2017 Nov;125(5):1569-1587 - PubMed
- Anesth Analg. 1970 Nov-Dec;49(6):924-34 - PubMed
- J Surg Res. 2016 May 1;202(1):165-76 - PubMed
- Anesthesiol Clin North Am. 2005 Mar;23(1):21-36 - PubMed
- Ann Surg. 2017 Apr;265(4):695-701 - PubMed
- J Gen Intern Med. 2017 Jun;32(6):632-639 - PubMed
- Health Psychol. 2013 Aug;32(8):905-14 - PubMed
- Pediatrics. 2010 Apr;125(4):e979-e1020 - PubMed
- Anesth Analg. 2020 Jul;131(1):255-262 - PubMed
- Eur J Pain. 2018 Apr;22(4):691-699 - PubMed
- Acta Anaesthesiol Scand. 2017 Mar;61(3):328-337 - PubMed
- Anesthesiology. 2016 Mar;124(3):608-23 - PubMed
- Plast Reconstr Surg. 2014 Oct;134(4 Suppl 2):15S-21S - PubMed
- Paediatr Anaesth. 2018 Feb;28(2):134-141 - PubMed
- Anesth Analg. 2002 Sep;95(3):627-34, table of contents - PubMed
- Hosp Pediatr. 2015 Jan;5(1):18-26 - PubMed
- Acad Pediatr. 2013 May-Jun;13(3):191-203 - PubMed
- Clin J Pain. 2017 Jul;33(7):604-610 - PubMed
- Pain Res Manag. 2008 Jan-Feb;13(1):25-32 - PubMed
- Korean J Anesthesiol. 2018 Oct;71(5):345-352 - PubMed
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