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Showing 1 to 12 of 89 entries
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Fecal microbiota transplant for Clostridium difficile infection in older adults.

Therapeutic advances in gastroenterology

Tauxe WM, Haydek JP, Rebolledo PA, Neish E, Newman KL, Ward A, Dhere T, Kraft CS.
PMID: 27134658
Therap Adv Gastroenterol. 2016 May;9(3):273-81. doi: 10.1177/1756283X15622600. Epub 2015 Dec 31.

BACKGROUND: The objective of this study was to describe the safety of fecal microbiota transplant (FMT) for Clostridium difficile infection (CDI) among older adults.METHODS: We performed a case review of all FMT recipients aged 65 or older treated at...

A systematic pipeline for the objective comparison of whole-brain spectroscopic MRI with histology in biopsy specimens from grade III glioma.

Tomography (Ann Arbor, Mich.)

Cordova JS, Gurbani SS, Olson JJ, Liang Z, Cooper LA, Shu HG, Schreibmann E, Neill SG, Hadjipanayis CG, Holder CA, Shim H.
PMID: 27489883
Tomography. 2016 Jun;2(2):106-116. doi: 10.18383/j.tom.2016.00136.

The diagnosis, prognosis, and management of patients with gliomas are largely dictated by the pathological analysis of tissue biopsied from a selected region within the lesion. However, due to the heterogeneous and infiltrative nature of gliomas, identifying the optimal...

Mitotic Origins of Chromosomal Instability in Colorectal Cancer.

Current colorectal cancer reports

Dalton WB, Yang VW.
PMID: 18843382
Curr Colorectal Cancer Rep. 2007 Apr;3(2):59-64. doi: 10.1007/s11888-007-0001-y.

Mitosis is a crucial part of the cell cycle. A successful mitosis requires the proper execution of many complex cellular behaviors. Thus, there are many points at which mitosis may be disrupted. In cancer cells, chronic disruption of mitosis...

Selective stimulation of the spinal cord surface using a stretchable microelectrode array.

Frontiers in neuroengineering

Meacham KW, Guo L, Deweerth SP, Hochman S.
PMID: 21541256
Front Neuroeng. 2011 Apr 21;4:5. doi: 10.3389/fneng.2011.00005. eCollection 2011.

By electrically stimulating the spinal cord, it is possible to activate functional populations of neurons that modulate motor and sensory function. One method for accessing these neurons is via their associated axons, which project as functionally segregated longitudinal columns...

Not all depression is created equal: sex interacts with disease to precipitate depression.

Biology of sex differences

Nemeth CL, Harrell CS, Beck KD, Neigh GN.
PMID: 23594674
Biol Sex Differ. 2013 Apr 17;4(1):8. doi: 10.1186/2042-6410-4-8.

Depression is a common mental disorder that co-occurs in other neurological and somatic diseases. Further, sex differences exist in the prevalence rates of many of these diseases, as well as within non-disease associated depression. In this review, the case...

WITHDRAWN: The Cosmc connection to the Tn antigen in cancer.

Disease markers

Ju T, Aryal RP, Kudelka MR, Wang Y, Cummings RD.
PMID: 23478278
Dis Markers. 2013 Mar 11; doi: 10.3233/DMA-130973. Epub 2013 Mar 11.

Ahead of Print article withdrawn by publisher. At request of the authors, this article will be published in the journal Cancer Biomarkers (ISSN 1574-0153).

Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation.

ACS chemical neuroscience

Davis AA, Heilman CJ, Brady AE, Miller NR, Fuerstenau-Sharp M, Hanson BJ, Lindsley CW, Conn PJ, Lah JJ, Levey AI.
PMID: 20835371
ACS Chem Neurosci. 2010 Aug 18;1(8):542-551. doi: 10.1021/cn100011e.

Muscarinic acetylcholine receptors (mAChRs) are drug targets for multiple neurodegenerative and neuropsychiatric disorders, but the full therapeutic potential of mAChR-targeted drugs has not been realized, mainly because of a lack of subtype-selective agonists. Recent advances have allowed the development...

Open forum infectious diseases

Peterson MS, Joyner CJ, Cordy RJ, Salinas JL, Machiah D, Lapp SA, Meyer EVS, Gumber S, Galinski MR.
PMID: 30937329
Open Forum Infect Dis. 2019 Jan 19;6(3):ofz021. doi: 10.1093/ofid/ofz021. eCollection 2019 Mar.

METHODS: We present quantitative parasitological and histopathological analyses of tissue sections from a cohort of naive, mostly splenectomized RESULTS: The lung, liver, and kidney showed the most tissue injury, with pathological presentations similar to observations reported from autopsies. Parasite...

Inhaled bacteriophage-loaded polymeric microparticles ameliorate acute lung infections.

Nature biomedical engineering

Agarwal R, Johnson CT, Imhoff BR, Donlan RM, McCarty NA, García AJ.
PMID: 30854250
Nat Biomed Eng. 2018 Nov;2(11):841-849. doi: 10.1038/s41551-018-0263-5. Epub 2018 Jul 16.

No abstract available.

Thermally multiplexed polymerase chain reaction.

Biomicrofluidics

Phaneuf CR, Pak N, Saunders DC, Holst GL, Birjiniuk J, Nagpal N, Culpepper S, Popler E, Shane AL, Jerris R, Forest CR.
PMID: 26339317
Biomicrofluidics. 2015 Aug 10;9(4):044117. doi: 10.1063/1.4928486. eCollection 2015 Jul.

Amplification of multiple unique genetic targets using the polymerase chain reaction (PCR) is commonly required in molecular biology laboratories. Such reactions are typically performed either serially or by multiplex PCR. Serial reactions are time consuming, and multiplex PCR, while...

LRRK2 levels in immune cells are increased in Parkinson's disease.

NPJ Parkinson's disease

Cook DA, Kannarkat GT, Cintron AF, Butkovich LM, Fraser KB, Chang J, Grigoryan N, Factor SA, West AB, Boss JM, Tansey MG.
PMID: 28649611
NPJ Parkinsons Dis. 2017 Mar 28;3:11. doi: 10.1038/s41531-017-0010-8. eCollection 2017.

Mutations associated with leucine-rich repeat kinase 2 are the most common known cause of Parkinson's disease. The known expression of leucine-rich repeat kinase 2 in immune cells and its negative regulatory function of nuclear factor of activated T cells...

Peroxiredoxins in Cancer and Response to Radiation Therapies.

Antioxidants (Basel, Switzerland)

Forshaw TE, Holmila R, Nelson KJ, Lewis JE, Kemp ML, Tsang AW, Poole LB, Lowther WT, Furdui CM.
PMID: 30609657
Antioxidants (Basel). 2019 Jan 01;8(1). doi: 10.3390/antiox8010011.

Peroxiredoxins have a long-established cellular function as regulators of redox metabolism by catalyzing the reduction of peroxides (e.g., H₂O₂, lipid peroxides) with high catalytic efficiency. This activity is also critical to the initiation and relay of both phosphorylation and...

Showing 1 to 12 of 89 entries