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Showing 1 to 12 of 13 entries
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Origin and evolution of the T cell repertoire after posttransplantation cyclophosphamide.

JCI insight

Kanakry CG, Coffey DG, Towlerton AM, Vulic A, Storer BE, Chou J, Yeung CC, Gocke CD, Robins HS, O'Donnell PV, Luznik L, Warren EH.
PMID: 27213183
JCI Insight. 2016;1(5). doi: 10.1172/jci.insight.86252. Epub 2016 Apr 21.

Posttransplantation cyclophosphamide (PTCy) effectively prevents graft-versus-host disease (GVHD), but its immunologic impact is poorly understood. We assessed lymphocyte reconstitution via flow cytometry (

Therapeutic dilemma in the management of a patient with the clinical picture of TTP and severe B12 deficiency.

BMC hematology

Walter K, Vaughn J, Martin D.
PMID: 26634125
BMC Hematol. 2015 Dec 01;15:16. doi: 10.1186/s12878-015-0036-2. eCollection 2015.

BACKGROUND: Idiopathic thrombotic thrombocytopenic purpura (TTP) is a rare hematological emergency characterized by the pentad of microangiopathic hemolytic anemia, thrombocytopenia, neurological symptoms, renal injury, and fever that is invariably fatal if left untreated. Prompt intervention with plasma exchange minimizes...

Hematopoietic Cell Transplantation for Older Patients with MDS.

Mediterranean journal of hematology and infectious diseases

Shadman M, Deeg HJ.
PMID: 25237469
Mediterr J Hematol Infect Dis. 2014 Sep 01;6(1):e2014056. doi: 10.4084/MJHID.2014.056. eCollection 2014.

The incidence of myeloid malignancies, including myelodysplastic syndromes (MDS) increases with age. While several therapeutic modalities have been developed, for most of these patients the only treatment with curative potential is allogeneic hematopoietic cell transplantation (HCT). The development of...

Diagnostic and therapeutic challenges of EBV-positive mucocutaneous ulcer: a case report and systematic review of the literature.

Experimental hematology & oncology

Roberts TK, Chen X, Liao JJ.
PMID: 27127726
Exp Hematol Oncol. 2016 Apr 27;5:13. doi: 10.1186/s40164-016-0042-5. eCollection 2015.

BACKGROUND: Epstein-Barr virus-positive mucocutaneous ulcer (EBVMCU) is a recently recognized B cell lymphoproliferative disorder that is driven by latent EBV infection and causes discrete ulcerations in the oropharynx, gastrointestinal tract, and skin. Local attenuation of immunosurveillance associated with iatrogenic...

Managing thrombosis in cancer patients.

Research and practice in thrombosis and haemostasis

Wang TF, Li A, Garcia D.
PMID: 30046747
Res Pract Thromb Haemost. 2018 May 01;2(3):429-438. doi: 10.1002/rth2.12102. eCollection 2018 Jul.

Venous thromboembolism is a major complication in cancer patients. The basis for the strong association between cancer and thrombosis remains incompletely understood, and the optimal approaches to both the treatment and the prevention of cancer-associated thrombosis are evolving. Here...

Platelet trends after Covid-19 vaccination in patients with chronic or persistent immune thrombocytopenia.

American journal of hematology

Jiang D, Portuguese AJ, Weatherford A, Garcia D, Gernsheimer T.
PMID: 34619804
Am J Hematol. 2021 Dec 01;96(12):E472-E474. doi: 10.1002/ajh.26366. Epub 2021 Oct 19.

No abstract available.

Long-term survival with mixed chimerism in patients with AML and MDS transplanted after conditioning with targeted busulfan, fludarabine, and thymoglobulin.

Bone marrow transplantation

Yeh AC, O'Donnell PV, Schoch G, Martin PJ, McFarland C, McCune JS, Cooper JP, Doney K, Flowers MED, Sorror ML, Appelbaum FR, Storer BE, Gooley T, Deeg HJ.
PMID: 34741096
Bone Marrow Transplant. 2021 Nov 05; doi: 10.1038/s41409-021-01518-0. Epub 2021 Nov 05.

We evaluated long-term outcome in 40 patients with MDS or AML, transplanted from related or unrelated donors following conditioning with targeted busulfan (Bu, over 4 days), fludarabine (Flu, 120 [nā€‰=ā€‰23] or 250 [nā€‰=ā€‰17] mg/m

Management of venous thromboembolism during thrombocytopenia after autologous hematopoietic cell transplantation.

Blood advances

Li A, Davis C, Wu Q, Li S, Kesten MF, Holmberg LA, Gopal AK, Garcia DA.
PMID: 29296714
Blood Adv. 2017 Apr 27;1(12):707-714. doi: 10.1182/bloodadvances.2017006130. eCollection 2017 May 09.

Management of venous thromboembolism (VTE) remains challenging in patients with hematologic malignancy who undergo hematopoietic cell transplantation (HCT) due to prolonged thrombocytopenia. This study aims to (1) determine the incidence of VTE recurrence and bleeding during autologous HCT, (2)...

The Diving Bell and the Butterfly Revisited: A Fatal Case of Locked-in Syndrome in a Man With Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified.

Clinical medicine insights. Blood disorders

Poston JN, Dorer R, Aboulafia DM.
PMID: 29623003
Clin Med Insights Blood Disord. 2018 Mar 26;11:1179545X18762799. doi: 10.1177/1179545X18762799. eCollection 2018.

Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (DLBCL) is a rare variant of DLBCL. The natural history of this subtype is poorly understood. Incomplete literature in the era of rituximab suggests that patients with EBV-positive DLBCL have similar outcomes...

Burkitt lymphoma of the maxilla in a HIV positive male - Presentation and review of diagnostic laboratory tests.

Oral and maxillofacial surgery cases

Alvarez W, Lai LH, Grant SJ, Sabath DE, Dillon J.
PMID: 33282691
Oral Maxillofac Surg Cases. 2019 Sep;5(3). doi: 10.1016/j.omsc.2019.100113. Epub 2019 Jul 03.

Burkitt lymphoma (BL) is a highly aggressive, B cell non-Hodgkin lymphoma (NHL) that is rare outside Africa. We report a case of HIV-associated BL originating in the right maxillary sinus in a 31-year-old Hispanic male living in Washington, USA....

Acute Graft-Versus-Host Disease After Orthotopic Liver Transplantation: Predicting This Rare Complication Using Machine Learning.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Cooper JP, Perkins JD, Warner PR, Shingina A, Biggins SW, Abkowitz JL, Reyes JD.
PMID: 34587357
Liver Transpl. 2021 Sep 29; doi: 10.1002/lt.26318. Epub 2021 Sep 29.

Acute graft-versus-host disease (GVHD) is a rare complication after orthotopic liver transplantation (OLT) that carries high mortality. We hypothesized that machine-learning algorithms to predict rare events would identify patients at high risk for developing GVHD. To develop a predictive...

Acute Graft-Versus-Host Disease After Orthotopic Liver Transplantation: Predicting This Rare Complication Using Machine Learning.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Cooper JP, Perkins JD, Warner PR, Shingina A, Biggins SW, Abkowitz JL, Reyes JD.
PMID: 34587357
Liver Transpl. 2021 Sep 29; doi: 10.1002/lt.26318. Epub 2021 Sep 29.

Acute graft-versus-host disease (GVHD) is a rare complication after orthotopic liver transplantation (OLT) that carries high mortality. We hypothesized that machine-learning algorithms to predict rare events would identify patients at high risk for developing GVHD. To develop a predictive...

Showing 1 to 12 of 13 entries