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Kanakry CG, Coffey DG, Towlerton AM, et al. Origin and evolution of the T cell repertoire after posttransplantation cyclophosphamide. JCI Insight. 2016;1(5)doi: 10.1172/jci.insight.86252.
Kanakry, C. G., Coffey, D. G., Towlerton, A. M., Vulic, A., Storer, B. E., Chou, J., Yeung, C. C., Gocke, C. D., Robins, H. S., O'Donnell, P. V., Luznik, L., & Warren, E. H. (2016). Origin and evolution of the T cell repertoire after posttransplantation cyclophosphamide. JCI insight, 1(5), . https://doi.org/10.1172/jci.insight.86252
Kanakry, Christopher G, et al. "Origin and evolution of the T cell repertoire after posttransplantation cyclophosphamide." JCI insight vol. 1,5 (2016). doi: https://doi.org/10.1172/jci.insight.86252
Kanakry CG, Coffey DG, Towlerton AM, Vulic A, Storer BE, Chou J, Yeung CC, Gocke CD, Robins HS, O'Donnell PV, Luznik L, Warren EH. Origin and evolution of the T cell repertoire after posttransplantation cyclophosphamide. JCI Insight. 2016;1(5). doi: 10.1172/jci.insight.86252. Epub 2016 Apr 21. PMID: 27213183; PMCID: PMC4874509.
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JCI Insight. 2016;1(5). doi: 10.1172/jci.insight.86252. Epub 2016 Apr 21.

Origin and evolution of the T cell repertoire after posttransplantation cyclophosphamide.

JCI insight

Christopher G Kanakry, David G Coffey, Andrea M H Towlerton, Ante Vulic, Barry E Storer, Jeffrey Chou, Cecilia C S Yeung, Christopher D Gocke, Harlan S Robins, Paul V O'Donnell, Leo Luznik, Edus H Warren

Affiliations

  1. Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  2. Clinical Research Division, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, Washington, USA; Department of Medicine, University of Washington, Seattle, Washington, USA.
  3. Clinical Research Division, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, Washington, USA.
  4. Clinical Research Division, Fred Hutchinson Cancer Research Center (FHCRC), Seattle, Washington, USA; Department of Pathology, University of Washington, Seattle, Washington, USA.
  5. Public Health Sciences Division, FHCRC, Seattle, Washington, USA.

PMID: 27213183 PMCID: PMC4874509 DOI: 10.1172/jci.insight.86252

Abstract

Posttransplantation cyclophosphamide (PTCy) effectively prevents graft-versus-host disease (GVHD), but its immunologic impact is poorly understood. We assessed lymphocyte reconstitution via flow cytometry (

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