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Showing 1 to 12 of 83 entries
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Assessment of second-line treatments for patients with uncontrolled moderate asthma.

International journal of clinical and experimental medicine

Wang K, Tian P, Fan Y, Wang Y, Liu C.
PMID: 26770595
Int J Clin Exp Med. 2015 Oct 15;8(10):19476-80. eCollection 2015.

AIM: To evaluate the best second-line treatments for patients with uncontrolled moderate asthma.METHODS: A single-center, random study was conducted in adult patients with uncontrolled moderate asthma to evaluate the effects of add-on treatments. After add-on treatments for 4 and...

Investigation of the efficacy of generic and brand-name tiotropium bromide in the management of chronic obstructive pulmonary disease: A randomized comparative trial.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Panahi Y, Ghanei M, Behzadi M, Salehi M, Soflaei SS, Sahebkar A.
PMID: 27013907
Saudi Pharm J. 2016 Mar;24(2):147-52. doi: 10.1016/j.jsps.2015.01.005. Epub 2015 Jan 12.

INTRODUCTION: The beneficial effects of tiotropium bromide, a long acting anticholinergic bronchodilator, in the management of chronic obstructive pulmonary disease have been shown in previous studies. The present study aimed to compare the efficacy and safety of generic (Tiova®)...

Instant velocity and consistency of emitted cloud change by the different levels of canister filling with Metered Dose Inhalers (MDIs), but not with Soft Mist Inhalers (SMIs): a bench study.

Multidisciplinary respiratory medicine

Dal Negro RW, Longo P, Ziani OV, Bonadiman L, Turco P.
PMID: 28560037
Multidiscip Respir Med. 2017 May 29;12:13. doi: 10.1186/s40248-017-0096-1. eCollection 2017.

BACKGROUND: Inhalation is the preferred route for respiratory drug delivery, but several factors contribute to the variability of the respirable dose fraction. Instant velocity and the dynamic characteristics of the droplet cloud represent crucial factors. Aim was to measure...

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Bayés M, Rabasseda X, Prous JR.
PMID: 16082422
Methods Find Exp Clin Pharmacol. 2005 Jun;27(5):331-72.

Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the following tables have been retrieved from the Clinical Trials Knowledge Area of Prous Science Integrity, the drug...

Gateways to clinical trials. July-August 2008.

Methods and findings in experimental and clinical pharmacology

Tomillero A, Moral MA.
PMID: 18850047
Methods Find Exp Clin Pharmacol. 2008 Jul-Aug;30(6):459-95.

(-)-Epigallocatechin gallate, 501516, 89-12; Abatacept, Adalimumab, Adefovir dipivoxil, AG-701, Agatolimod sodium, Alefacept, Aliskiren fumarate, Apixaban, Atazanavir sulfate, Atrasentan, Axitinib; BI-1744-CL, BIBF-1120, BIBW-2992, Bortezomib; Carboxyamidotriazole, Caspofungin acetate, CBP-501, Cediranib, Ceftobiprole, Certolizumab pegol, Cetuximab, Cholesteryl hydrophobized polysaccharide-Her2 protein complex, CHP-NY-ESO-1, Cypher;...

Retraction: Use of tiotropium bromide for pre-operative treatment in chronic obstructive pulmonary disease patients: comparison with oxitropium bromide.

Internal medicine (Tokyo, Japan)

Matsuyama W, Mitsuyama H, Koreeda Y, Higashimoto I, Osame M, Arimura K.
PMID: 18825845
Intern Med. 2008;47(14):1371. doi: 10.2169/internalmedicine.47.r001.

No abstract available.

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Tomillero A, Moral MA.
PMID: 20508873
Methods Find Exp Clin Pharmacol. 2010 May;32(4):247-88. doi: 10.1358/mf.2010.32.4.1507200.

O(6)-Benzylguanine; (-)-Gossypol; Abatacept, AC-2592, Adalimumab, AIDSVAX gp120 B/E, Alemtuzumab, Aliskiren fumarate, ALVAC E120TMG, Ambrisentan, Amlodipine, Anakinra, Aripiprazole, Armodafinil, Atomoxetine hydrochloride, Avotermin; Bevacizumab, BIBW-2992, Bortezomib, Bosentan, Botulinum toxin type B; Canakinumab, CAT-354, Ciclesonide, CMV gB vaccine, Corifollitropin alfa, Daptomycin, Darbepoetin...

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology

Bayes M, Rabasseda X, Prous JR.
PMID: 18040531
Methods Find Exp Clin Pharmacol. 2007 Oct;29(8):547-83.

(-)-Epigallocatechin gallate, [188Re]-P2045, 12B75, 89-12; Abacavir sulfate/lamivudine, Abatacept, Abiraterone acetate, ABT-869, Adalimumab, Ad-rh Endostatin, AI-700, Alemtuzumab, Alvimopan hydrate, Amrubicin hydrochloride, AP-12009, Apomab 7.3, Arformoterol tartrate, Aripiprazole, AS-1404, Azacitidine, AZD-0530; Bevacizumab, BHT-3009, Biapenem, Bortezomib, Bosentan, Bremelanotide; CA9-SCAN, Calcitonin gene-related peptide,...

The role of tiotropium in the management of asthma.

Asia Pacific allergy

Park HW.
PMID: 22701860
Asia Pac Allergy. 2012 Apr;2(2):109-14. doi: 10.5415/apallergy.2012.2.2.109. Epub 2012 Apr 30.

Asthma is a chronic respiratory disease characterized by reversible airway obstruction that is secondary to an allergic inflammation and excessive smooth muscle contraction. Cholinergic signals were known to contribute significantly to the pathophysiology of asthma. However, the use of...

The role of indacaterol for chronic obstructive pulmonary disease (COPD).

Journal of thoracic disease

Cazzola M, Bardaro F, Stirpe E.
PMID: 23991316
J Thorac Dis. 2013 Aug;5(4):559-66. doi: 10.3978/j.issn.2072-1439.2013.07.35.

Indacaterol is the first long-acting β2-agonist (LABAs) approved for the treatment of chronic obstructive pulmonary disease (COPD) that allows for once-daily (OD) administration. It is rapidly acting, with an onset of action in 5 minutes, like salbutamol and formoterol...

Tiotropium in asthma: back to the future of anticholinergic treatment.

Clinical and molecular allergy : CMA

Bonini M, Scichilone N.
PMID: 29213218
Clin Mol Allergy. 2017 Dec 04;15:20. doi: 10.1186/s12948-017-0076-1. eCollection 2017.

Asthma is among the most common chronic diseases worldwide; however, despite progresses in the understanding of the patho-physiological mechanisms and advances in the development of new therapeutic options and strategies, the disease remains uncontrolled in a not trivial proportion...

Tiotropium Bromide Attenuates Mucus Hypersecretion in Patients with Stable Chronic Obstructive Pulmonary Disease.

Computational and mathematical methods in medicine

Yu S, Zhang C, Yan Z, Fang Q, Gao X.
PMID: 34650619
Comput Math Methods Med. 2021 Oct 05;2021:1341644. doi: 10.1155/2021/1341644. eCollection 2021.

BACKGROUND: Patients with stable chronic obstructive pulmonary disease (COPD) have been observed to benefit from tiotropium bromide. However, there are few studies of tiotropium bromide on sputum and sputum viscosity. To evaluate the effect of tiotropium bromide on mucus...

Showing 1 to 12 of 83 entries