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Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial

evaluation

Parsons MW, Levi C.
GSID: z86lng8dYwkJ
SM Davis, GA Donnan, MW Parsons, C Levi… - The Lancet …, 2008 - Elsevier

Background Whether intravenous tissue plasminogen activator (alteplase) is effective beyond 3 h after onset of acute ischaemic stroke is unclear. We aimed to test whether alteplase given 3–6 h after stroke onset promotes reperfusion and attenuates infarct growth in...

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Davis, S. M., Donnan, G. A., Parsons, M. W., Levi, C., Butcher, K. S., Peeters, A., ... & Desmond, P. M. (2008). Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. The Lancet Neurology, 7(4), 299-309.
Davis, Stephen M., et al. "Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial." The Lancet Neurology 7.4 (2008): 299-309.
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Integrated brain restoration after ischemic stroke--medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain …

Stem career interventions

[No authors listed]
GSID: W6AZFw8gGRkJ
PM Kidd - Alternative Medicine Review, 2009 - search.ebscohost.com

Brain injury from ischemic stroke can be devastating, but full brain restoration is feasible. Time until treatment is critical; rapid rate of injury progression, logistical and personnel constraints on neurological and cardiovascular assessment, limitations of recombinant tissue plasminogen activator...

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Kidd, P. M. (2009). Integrated brain restoration after ischemic stroke--medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain plasticity. Alternative Medicine Review, 14(1).
Kidd, Parris M. "Integrated brain restoration after ischemic stroke--medical management, risk factors, nutrients, and other interventions for managing inflammation and enhancing brain plasticity." Alternative Medicine Review 14.1 (2009).
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Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids.

Aging and disease

Cai M, Zhang W, Weng Z, Stetler RA, Jiang X, Shi Y, Gao Y, Chen J.
PMID: 28966799
Aging Dis. 2017 Oct 01;8(5):531-545. doi: 10.14336/AD.2017.0520. eCollection 2017 Oct.

The aged population is among the highest at risk for ischemic stroke, yet most stroke patients of advanced ages (>80 years) are excluded from access to thrombolytic treatment by tissue plasminogen activator, the only FDA approved pharmacological therapy for...

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Cai M, Zhang W, Weng Z, et al. Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids. Aging Dis. 2017;8(5):531-545doi: 10.14336/AD.2017.0520.
Cai, M., Zhang, W., Weng, Z., Stetler, R. A., Jiang, X., Shi, Y., Gao, Y., & Chen, J. (2017). Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids. Aging and disease, 8(5), 531-545. https://doi.org/10.14336/AD.2017.0520
Cai, Mengfei, et al. "Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids." Aging and disease vol. 8,5 (2017): 531-545. doi: https://doi.org/10.14336/AD.2017.0520
Cai M, Zhang W, Weng Z, Stetler RA, Jiang X, Shi Y, Gao Y, Chen J. Promoting Neurovascular Recovery in Aged Mice after Ischemic Stroke - Prophylactic Effect of Omega-3 Polyunsaturated Fatty Acids. Aging Dis. 2017 Oct 01;8(5):531-545. doi: 10.14336/AD.2017.0520. eCollection 2017 Oct. PMID: 28966799; PMCID: PMC5614319.
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Outcomes of patients with large middle cerebral artery infarct treated with and without intravenous thrombolysis.

Journal of neurosciences in rural practice

Dharmasaroja PA, Muengtaweepongsa S.
PMID: 26933341
J Neurosci Rural Pract. 2016 Jan-Mar;7(1):36-9. doi: 10.4103/0976-3147.172149.

BACKGROUND: Many thrombolytic studies showed that severe stroke was associated with death and having symptomatic intracerebral hemorrhage and inversely related to a favorable outcome.AIMS: The purpose of this study is to compare the outcomes of patients with acute large...

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Dharmasaroja PA, Muengtaweepongsa S. Outcomes of patients with large middle cerebral artery infarct treated with and without intravenous thrombolysis. J Neurosci Rural Pract. 2016;7(1):36-9doi: 10.4103/0976-3147.172149.
Dharmasaroja, P. A., & Muengtaweepongsa, S. (2016). Outcomes of patients with large middle cerebral artery infarct treated with and without intravenous thrombolysis. Journal of neurosciences in rural practice, 7(1), 36-9. https://doi.org/10.4103/0976-3147.172149
Dharmasaroja, Pornpatr A, and Muengtaweepongsa, Sombat. "Outcomes of patients with large middle cerebral artery infarct treated with and without intravenous thrombolysis." Journal of neurosciences in rural practice vol. 7,1 (2016): 36-9. doi: https://doi.org/10.4103/0976-3147.172149
Dharmasaroja PA, Muengtaweepongsa S. Outcomes of patients with large middle cerebral artery infarct treated with and without intravenous thrombolysis. J Neurosci Rural Pract. 2016 Jan-Mar;7(1):36-9. doi: 10.4103/0976-3147.172149. PMID: 26933341; PMCID: PMC4750336.
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Feasibility and efficacy of thrombolysis in acute ischemic stroke: A study from National Institute of Neurological and Allied Sciences, Kathmandu, Nepal.

Journal of neurosciences in rural practice

Thapa L, Shrestha S, Shrestha P, Bhattarai S, Gongal DN, Devkota UP.
PMID: 26933345
J Neurosci Rural Pract. 2016 Jan-Mar;7(1):55-60. doi: 10.4103/0976-3147.172161.

BACKGROUND: Stroke is the major cause of morbidity and mortality worldwide. The number of stroke patients receiving recombinant tissue plasminogen activator (rt-PA), also known as Alteplase, in the developing world is extremely low. We aim to study the feasibility...

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Thapa L, Shrestha S, Shrestha P, et al. Feasibility and efficacy of thrombolysis in acute ischemic stroke: A study from National Institute of Neurological and Allied Sciences, Kathmandu, Nepal. J Neurosci Rural Pract. 2016;7(1):55-60doi: 10.4103/0976-3147.172161.
Thapa, L., Shrestha, S., Shrestha, P., Bhattarai, S., Gongal, D. N., & Devkota, U. P. (2016). Feasibility and efficacy of thrombolysis in acute ischemic stroke: A study from National Institute of Neurological and Allied Sciences, Kathmandu, Nepal. Journal of neurosciences in rural practice, 7(1), 55-60. https://doi.org/10.4103/0976-3147.172161
Thapa, Lekhjung, et al. "Feasibility and efficacy of thrombolysis in acute ischemic stroke: A study from National Institute of Neurological and Allied Sciences, Kathmandu, Nepal." Journal of neurosciences in rural practice vol. 7,1 (2016): 55-60. doi: https://doi.org/10.4103/0976-3147.172161
Thapa L, Shrestha S, Shrestha P, Bhattarai S, Gongal DN, Devkota UP. Feasibility and efficacy of thrombolysis in acute ischemic stroke: A study from National Institute of Neurological and Allied Sciences, Kathmandu, Nepal. J Neurosci Rural Pract. 2016 Jan-Mar;7(1):55-60. doi: 10.4103/0976-3147.172161. PMID: 26933345; PMCID: PMC4750341.
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Tirofiban facilitates the reperfusion process during endovascular thrombectomy in ICAS.

Experimental and therapeutic medicine

Zhao H, Zhang J, Gu D, Shi Z, Pan J, Geng Y, Shi T.
PMID: 28912883
Exp Ther Med. 2017 Oct;14(4):3314-3318. doi: 10.3892/etm.2017.4856. Epub 2017 Jul 31.

The aim of the present study was to assess the use of tirofiban injections for rescue therapy following artery reocclusion due to intra-luminal thrombosis during endovascular thrombectomy in patients with acute ischemic stroke (AIS). A total of seven cases...

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Zhao H, Zhang J, Gu D, et al. Tirofiban facilitates the reperfusion process during endovascular thrombectomy in ICAS. Exp Ther Med. 2017;14(4):3314-3318doi: 10.3892/etm.2017.4856.
Zhao, H., Zhang, J., Gu, D., Shi, Z., Pan, J., Geng, Y., & Shi, T. (2017). Tirofiban facilitates the reperfusion process during endovascular thrombectomy in ICAS. Experimental and therapeutic medicine, 14(4), 3314-3318. https://doi.org/10.3892/etm.2017.4856
Zhao, Hongchen, et al. "Tirofiban facilitates the reperfusion process during endovascular thrombectomy in ICAS." Experimental and therapeutic medicine vol. 14,4 (2017): 3314-3318. doi: https://doi.org/10.3892/etm.2017.4856
Zhao H, Zhang J, Gu D, Shi Z, Pan J, Geng Y, Shi T. Tirofiban facilitates the reperfusion process during endovascular thrombectomy in ICAS. Exp Ther Med. 2017 Oct;14(4):3314-3318. doi: 10.3892/etm.2017.4856. Epub 2017 Jul 31. PMID: 28912883; PMCID: PMC5585762.
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Central Venous Catheters for Hemodialysis: How to Overcome the Problems.

Hemodialysis international. International Symposium on Home Hemodialysis

Davenport A.
PMID: 28455926
Hemodial Int. 2000 Jan;4(1):78-82. doi: 10.1111/hdi.2000.4.1.78.

The use of central venous dialysis catheters is increasing in clinical practice. These devices, although relatively easy to insert, do have problems. Catheter size limits the amount of dialysis that can be delivered. Central venous hemodialysis catheters minimize cardiopulmonary...

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Davenport A. Central Venous Catheters for Hemodialysis: How to Overcome the Problems. Hemodial Int. 2000;4(1):78-82doi: 10.1111/hdi.2000.4.1.78.
Davenport, A. (2000). Central Venous Catheters for Hemodialysis: How to Overcome the Problems. Hemodialysis international. International Symposium on Home Hemodialysis, 4(1), 78-82. https://doi.org/10.1111/hdi.2000.4.1.78
Davenport, Andrew. "Central Venous Catheters for Hemodialysis: How to Overcome the Problems." Hemodialysis international. International Symposium on Home Hemodialysis vol. 4,1 (2000): 78-82. doi: https://doi.org/10.1111/hdi.2000.4.1.78
Davenport A. Central Venous Catheters for Hemodialysis: How to Overcome the Problems. Hemodial Int. 2000 Jan;4(1):78-82. doi: 10.1111/hdi.2000.4.1.78. PMID: 28455926.
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Safety of Intraventricular rt-PA for Pan-Ventricular IVH Caused by a Ruptured AVM: A Case Report.

The Neurohospitalist

Dharmadhikari S, Mahapatra A, Tipirneni A, Yavagal D, Malik AM.
PMID: 28975005
Neurohospitalist. 2017 Oct;7(4):NP5-NP8. doi: 10.1177/1941874416689363. Epub 2017 Jan 31.

Intraventricular recombinant tissue plasminogen activator (IVT rt-PA) has improved outcomes for intraventricular hemorrhage (IVH). Patients with suspected or untreated arteriovenous malformations (AVMs) have been excluded from clinical trials. We present a patient with IVH secondary to a ruptured AVM...

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Dharmadhikari S, Mahapatra A, Tipirneni A, et al. Safety of Intraventricular rt-PA for Pan-Ventricular IVH Caused by a Ruptured AVM: A Case Report. Neurohospitalist. 2017;7(4):NP5-NP8doi: 10.1177/1941874416689363.
Dharmadhikari, S., Mahapatra, A., Tipirneni, A., Yavagal, D., & Malik, A. M. (2017). Safety of Intraventricular rt-PA for Pan-Ventricular IVH Caused by a Ruptured AVM: A Case Report. The Neurohospitalist, 7(4), NP5-NP8. https://doi.org/10.1177/1941874416689363
Dharmadhikari, Sushrut, et al. "Safety of Intraventricular rt-PA for Pan-Ventricular IVH Caused by a Ruptured AVM: A Case Report." The Neurohospitalist vol. 7,4 (2017): NP5-NP8. doi: https://doi.org/10.1177/1941874416689363
Dharmadhikari S, Mahapatra A, Tipirneni A, Yavagal D, Malik AM. Safety of Intraventricular rt-PA for Pan-Ventricular IVH Caused by a Ruptured AVM: A Case Report. Neurohospitalist. 2017 Oct;7(4):NP5-NP8. doi: 10.1177/1941874416689363. Epub 2017 Jan 31. PMID: 28975005; PMCID: PMC5613868.
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Surgical embolectomy for middle cerebral artery occlusion after thrombolytic therapy: A report of two cases.

Surgical neurology international

Katsuno M, Kawasaki K, Izumi N, Hashimoto M.
PMID: 25024893
Surg Neurol Int. 2014 Jun 13;5:93. doi: 10.4103/2152-7806.134520. eCollection 2014.

BACKGROUND: Occlusion of the intracranial main trunk results in a poor functional outcome and a high mortality rate. Accordingly, some revascularization procedures such as intravenous administration of recombinant tissue plasminogen activator (rt-PA), endovascular surgery, or surgical embolectomy in the...

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Katsuno M, Kawasaki K, Izumi N, et al. Surgical embolectomy for middle cerebral artery occlusion after thrombolytic therapy: A report of two cases. Surg Neurol Int. 2014;5:93doi: 10.4103/2152-7806.134520.
Katsuno, M., Kawasaki, K., Izumi, N., & Hashimoto, M. (2014). Surgical embolectomy for middle cerebral artery occlusion after thrombolytic therapy: A report of two cases. Surgical neurology international, 593. https://doi.org/10.4103/2152-7806.134520
Katsuno, Makoto, et al. "Surgical embolectomy for middle cerebral artery occlusion after thrombolytic therapy: A report of two cases." Surgical neurology international vol. 5 (2014): 93. doi: https://doi.org/10.4103/2152-7806.134520
Katsuno M, Kawasaki K, Izumi N, Hashimoto M. Surgical embolectomy for middle cerebral artery occlusion after thrombolytic therapy: A report of two cases. Surg Neurol Int. 2014 Jun 13;5:93. doi: 10.4103/2152-7806.134520. eCollection 2014. PMID: 25024893; PMCID: PMC4093772.
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Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics.

Drug delivery and translational research

Chi A, Curi S, Clayton K, Luciano D, Klauber K, Alexander-Katz A, D'hers S, Elman NM.
PMID: 25787065
Drug Deliv Transl Res. 2014 Aug;4(4):320-33. doi: 10.1007/s13346-014-0198-7.

Rapid Reconstitution Packages (RRPs) are portable platforms that integrate microfluidics for rapid reconstitution of lyophilized drugs. Rapid reconstitution of lyophilized drugs using standard vials and syringes is an error-prone process. RRPs were designed using computational fluid dynamics (CFD) techniques...

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Chi A, Curi S, Clayton K, et al. Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics. Drug Deliv Transl Res. 2014;4(4):320-33doi: 10.1007/s13346-014-0198-7.
Chi, A., Curi, S., Clayton, K., Luciano, D., Klauber, K., Alexander-Katz, A., D'hers, S., & Elman, N. M. (2014). Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics. Drug delivery and translational research, 4(4), 320-33. https://doi.org/10.1007/s13346-014-0198-7
Chi, Albert, et al. "Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics." Drug delivery and translational research vol. 4,4 (2014): 320-33. doi: https://doi.org/10.1007/s13346-014-0198-7
Chi A, Curi S, Clayton K, Luciano D, Klauber K, Alexander-Katz A, D'hers S, Elman NM. Rapid Reconstitution Packages (RRPs) implemented by integration of computational fluid dynamics (CFD) and 3D printed microfluidics. Drug Deliv Transl Res. 2014 Aug;4(4):320-33. doi: 10.1007/s13346-014-0198-7. PMID: 25787065.
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Oxidative Stress and the Use of Antioxidants in Stroke.

Antioxidants (Basel, Switzerland)

Shirley R, Ord EN, Work LM.
PMID: 26785066
Antioxidants (Basel). 2014 Jul 03;3(3):472-501. doi: 10.3390/antiox3030472.

Transient or permanent interruption of cerebral blood flow by occlusion of a cerebral artery gives rise to an ischaemic stroke leading to irreversible damage or dysfunction to the cells within the affected tissue along with permanent or reversible neurological...

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Shirley R, Ord EN, Work LM. Oxidative Stress and the Use of Antioxidants in Stroke. Antioxidants (Basel). 2014;3(3):472-501doi: 10.3390/antiox3030472.
Shirley, R., Ord, E. N., & Work, L. M. (2014). Oxidative Stress and the Use of Antioxidants in Stroke. Antioxidants (Basel, Switzerland), 3(3), 472-501. https://doi.org/10.3390/antiox3030472
Shirley, Rachel, et al. "Oxidative Stress and the Use of Antioxidants in Stroke." Antioxidants (Basel, Switzerland) vol. 3,3 (2014): 472-501. doi: https://doi.org/10.3390/antiox3030472
Shirley R, Ord EN, Work LM. Oxidative Stress and the Use of Antioxidants in Stroke. Antioxidants (Basel). 2014 Jul 03;3(3):472-501. doi: 10.3390/antiox3030472. PMID: 26785066; PMCID: PMC4665418.
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Comparison of outcomes of patients with inpatient or outpatient onset ischemic stroke.

Journal of neurointerventional surgery

Bekelis K, Missios S, Coy S, MacKenzie TA.
PMID: 26733583
J Neurointerv Surg. 2016 Dec;8(12):1221-1225. doi: 10.1136/neurintsurg-2015-012145. Epub 2016 Jan 05.

BACKGROUND: Reperfusion times for ischemic stroke occurring in the outpatient setting have improved significantly in recent years. However, quality improvement efforts have largely ignored ischemic stroke occurring in patients hospitalized for unrelated indications.METHODS: We performed a cohort study involving...

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Bekelis K, Missios S, Coy S, et al. Comparison of outcomes of patients with inpatient or outpatient onset ischemic stroke. J Neurointerv Surg. 2016;8(12):1221-1225doi: 10.1136/neurintsurg-2015-012145.
Bekelis, K., Missios, S., Coy, S., & MacKenzie, T. A. (2016). Comparison of outcomes of patients with inpatient or outpatient onset ischemic stroke. Journal of neurointerventional surgery, 8(12), 1221-1225. https://doi.org/10.1136/neurintsurg-2015-012145
Bekelis, Kimon, et al. "Comparison of outcomes of patients with inpatient or outpatient onset ischemic stroke." Journal of neurointerventional surgery vol. 8,12 (2016): 1221-1225. doi: https://doi.org/10.1136/neurintsurg-2015-012145
Bekelis K, Missios S, Coy S, MacKenzie TA. Comparison of outcomes of patients with inpatient or outpatient onset ischemic stroke. J Neurointerv Surg. 2016 Dec;8(12):1221-1225. doi: 10.1136/neurintsurg-2015-012145. Epub 2016 Jan 05. PMID: 26733583.
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Showing 1 to 12 of 1448 entries