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Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies.

Healthcare (Amsterdam, Netherlands)

Tuzzio L, Meyers CM, Dember LM, Grudzen CR, Melnick ER, Staman KL, Huang SS, Richards J, DeBar L, Vazquez MA, Green BB, Coronado GD, Jarvik JG, Braciszewski J, Ho PM, Wells BL, James K, Toto R, D'Onofrio G, Volandes A, Kuklinski MR, Catalano RF, Sterling SA, Morse EF, Curtis L, Larson EB.
PMID: 34175091
Healthc (Amst). 2021 Jun;8:100432. doi: 10.1016/j.hjdsi.2020.100432. Epub 2021 Jun 23.

Embedded pragmatic clinical trials (ePCTs) and quality improvement (QI) activities often occur simultaneously within healthcare systems (HCSs). Embedded PCTs within HCSs are conducted to test interventions and provide evidence that may impact public health, health system operations, and quality...

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Tuzzio L, Meyers CM, Dember LM, et al. Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthc (Amst). 2021;8:100432doi: 10.1016/j.hjdsi.2020.100432.
Tuzzio, L., Meyers, C. M., Dember, L. M., Grudzen, C. R., Melnick, E. R., Staman, K. L., Huang, S. S., Richards, J., DeBar, L., Vazquez, M. A., Green, B. B., Coronado, G. D., Jarvik, J. G., Braciszewski, J., Ho, P. M., Wells, B. L., James, K., Toto, R., D'Onofrio, G., Volandes, A., Kuklinski, M. R., Catalano, R. F., Sterling, S. A., Morse, E. F., Curtis, L., & Larson, E. B. (2021). Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthcare (Amsterdam, Netherlands), 8100432. https://doi.org/10.1016/j.hjdsi.2020.100432
Tuzzio, Leah, et al. "Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies." Healthcare (Amsterdam, Netherlands) vol. 8 (2021): 100432. doi: https://doi.org/10.1016/j.hjdsi.2020.100432
Tuzzio L, Meyers CM, Dember LM, Grudzen CR, Melnick ER, Staman KL, Huang SS, Richards J, DeBar L, Vazquez MA, Green BB, Coronado GD, Jarvik JG, Braciszewski J, Ho PM, Wells BL, James K, Toto R, D'Onofrio G, Volandes A, Kuklinski MR, Catalano RF, Sterling SA, Morse EF, Curtis L, Larson EB. Accounting for quality improvement during the conduct of embedded pragmatic clinical trials within healthcare systems: NIH Collaboratory case studies. Healthc (Amst). 2021 Jun;8:100432. doi: 10.1016/j.hjdsi.2020.100432. Epub 2021 Jun 23. PMID: 34175091.
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Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory.

Journal of the American Medical Informatics Association : JAMIA

Richesson RL, Marsolo KS, Douthit BJ, Staman K, Ho PM, Dailey D, Boyd AD, McTigue KM, Ezenwa MO, Schlaeger JM, Patil CL, Faurot KR, Tuzzio L, Larson EB, O'Brien EC, Zigler CK, Lakin JR, Pressman AR, Braciszewski JM, Grudzen C, Fiol GD.
PMID: 34597383
J Am Med Inform Assoc. 2021 Nov 25;28(12):2626-2640. doi: 10.1093/jamia/ocab202.

OBJECTIVE: We identified challenges and solutions to using electronic health record (EHR) systems for the design and conduct of pragmatic research.MATERIALS AND METHODS: Since 2012, the Health Care Systems Research Collaboratory has served as the resource coordinating center for...

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Richesson RL, Marsolo KS, Douthit BJ, et al. Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory. J Am Med Inform Assoc. 2021;28(12):2626-2640doi: 10.1093/jamia/ocab202.
Richesson, R. L., Marsolo, K. S., Douthit, B. J., Staman, K., Ho, P. M., Dailey, D., Boyd, A. D., McTigue, K. M., Ezenwa, M. O., Schlaeger, J. M., Patil, C. L., Faurot, K. R., Tuzzio, L., Larson, E. B., O'Brien, E. C., Zigler, C. K., Lakin, J. R., Pressman, A. R., Braciszewski, J. M., Grudzen, C., & Fiol, G. D. (2021). Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory. Journal of the American Medical Informatics Association : JAMIA, 28(12), 2626-2640. https://doi.org/10.1093/jamia/ocab202
Richesson, Rachel L, et al. "Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory." Journal of the American Medical Informatics Association : JAMIA vol. 28,12 (2021): 2626-2640. doi: https://doi.org/10.1093/jamia/ocab202
Richesson RL, Marsolo KS, Douthit BJ, Staman K, Ho PM, Dailey D, Boyd AD, McTigue KM, Ezenwa MO, Schlaeger JM, Patil CL, Faurot KR, Tuzzio L, Larson EB, O'Brien EC, Zigler CK, Lakin JR, Pressman AR, Braciszewski JM, Grudzen C, Fiol GD. Enhancing the use of EHR systems for pragmatic embedded research: lessons from the NIH Health Care Systems Research Collaboratory. J Am Med Inform Assoc. 2021 Nov 25;28(12):2626-2640. doi: 10.1093/jamia/ocab202. PMID: 34597383; PMCID: PMC8633608.
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Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018.

Canadian journal of kidney health and disease

Lee EJ, Patel A, Acedillo RR, Bachynski JC, Barrett I, Basile E, Battistella M, Benjamin D, Berry D, Blake PG, Chan P, Bohm CJ, Clemens KK, Cook C, Dember L, Dirk JS, Dixon S, Fowler E, Getchell L, Gholami N, Goldstein C, Hahn E, Hogeterp B, Huang S, Hughes M, Jardine MJ, Kalatharan S, Kilburn S, Lacson E, Leonard S, Liberty C, Lindsay C, MacRae JM, Manns BJ, McCallum J, McIntyre CW, Molnar AO, Mustafa RA, Nesrallah GE, Oliver MJ, Pandes M, Pandeya S, Parmar MS, Rabin EZ, Riley J, Silver SA, Sontrop JM, Sood MM, Suri RS, Tangri N, Tascona DJ, Thomas A, Wald R, Walsh M, Weijer C, Weir MA, Vorster H, Zimmerman D, Garg AX.
PMID: 31903190
Can J Kidney Health Dis. 2019 Dec 26;6:2054358119894394. doi: 10.1177/2054358119894394. eCollection 2019.

Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those on hemodialysis still face a poor quality of life and a short life expectancy. High-quality research evidence from large randomized controlled trials is needed to identify interventions...

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Lee EJ, Patel A, Acedillo RR, et al. Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018. Can J Kidney Health Dis. 2019;6:2054358119894394doi: 10.1177/2054358119894394.
Lee, E. J., Patel, A., Acedillo, R. R., Bachynski, J. C., Barrett, I., Basile, E., Battistella, M., Benjamin, D., Berry, D., Blake, P. G., Chan, P., Bohm, C. J., Clemens, K. K., Cook, C., Dember, L., Dirk, J. S., Dixon, S., Fowler, E., Getchell, L., Gholami, N., Goldstein, C., Hahn, E., Hogeterp, B., Huang, S., Hughes, M., Jardine, M. J., Kalatharan, S., Kilburn, S., Lacson, E., Leonard, S., Liberty, C., Lindsay, C., MacRae, J. M., Manns, B. J., McCallum, J., McIntyre, C. W., Molnar, A. O., Mustafa, R. A., Nesrallah, G. E., Oliver, M. J., Pandes, M., Pandeya, S., Parmar, M. S., Rabin, E. Z., Riley, J., Silver, S. A., Sontrop, J. M., Sood, M. M., Suri, R. S., Tangri, N., Tascona, D. J., Thomas, A., Wald, R., Walsh, M., Weijer, C., Weir, M. A., Vorster, H., Zimmerman, D., & Garg, A. X. (2019). Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018. Canadian journal of kidney health and disease, 62054358119894394. https://doi.org/10.1177/2054358119894394
Lee, Elliot J, et al. "Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018." Canadian journal of kidney health and disease vol. 6 (2019): 2054358119894394. doi: https://doi.org/10.1177/2054358119894394
Lee EJ, Patel A, Acedillo RR, Bachynski JC, Barrett I, Basile E, Battistella M, Benjamin D, Berry D, Blake PG, Chan P, Bohm CJ, Clemens KK, Cook C, Dember L, Dirk JS, Dixon S, Fowler E, Getchell L, Gholami N, Goldstein C, Hahn E, Hogeterp B, Huang S, Hughes M, Jardine MJ, Kalatharan S, Kilburn S, Lacson E, Leonard S, Liberty C, Lindsay C, MacRae JM, Manns BJ, McCallum J, McIntyre CW, Molnar AO, Mustafa RA, Nesrallah GE, Oliver MJ, Pandes M, Pandeya S, Parmar MS, Rabin EZ, Riley J, Silver SA, Sontrop JM, Sood MM, Suri RS, Tangri N, Tascona DJ, Thomas A, Wald R, Walsh M, Weijer C, Weir MA, Vorster H, Zimmerman D, Garg AX. Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018. Can J Kidney Health Dis. 2019 Dec 26;6:2054358119894394. doi: 10.1177/2054358119894394. eCollection 2019. PMID: 31903190; PMCID: PMC6933546.
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Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems.

Healthcare (Amsterdam, Netherlands)

Larson EB, Tachibana C, Thompson E, Coronado GD, DeBar L, Dember LM, Honda S, Huang SS, Jarvik JG, Nelson C, Septimus E, Simon G, Johnson KE.
PMID: 27637816
Healthc (Amst). 2016 Sep;4(3):138-41. doi: 10.1016/j.hjdsi.2015.07.005. Epub 2015 Jul 29.

Pragmatic clinical trials are increasingly common because they have the potential to yield findings that are directly translatable to real-world healthcare settings. Pragmatic clinical trials need to integrate research into clinical workflow without placing an undue burden on the...

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Larson EB, Tachibana C, Thompson E, et al. Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthc (Amst). 2015;4(3):138-41doi: 10.1016/j.hjdsi.2015.07.005.
Larson, E. B., Tachibana, C., Thompson, E., Coronado, G. D., DeBar, L., Dember, L. M., Honda, S., Huang, S. S., Jarvik, J. G., Nelson, C., Septimus, E., Simon, G., & Johnson, K. E. (2016). Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthcare (Amsterdam, Netherlands), 4(3), 138-41. https://doi.org/10.1016/j.hjdsi.2015.07.005
Larson, Eric B, et al. "Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems." Healthcare (Amsterdam, Netherlands) vol. 4,3 (2016): 138-41. doi: https://doi.org/10.1016/j.hjdsi.2015.07.005
Larson EB, Tachibana C, Thompson E, Coronado GD, DeBar L, Dember LM, Honda S, Huang SS, Jarvik JG, Nelson C, Septimus E, Simon G, Johnson KE. Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthc (Amst). 2016 Sep;4(3):138-41. doi: 10.1016/j.hjdsi.2015.07.005. Epub 2015 Jul 29. PMID: 27637816; PMCID: PMC5027068.
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Cultivating a Research-Ready Dialysis Community.

Journal of the American Society of Nephrology : JASN

Flythe JE, Narendra JH, Hilliard T, Frazier K, Ikeler K, Amolegbe A, Mitchell D, Dorough A, Lee SD, Ordish A, Wilkie C, Dember LM.
PMID: 30737271
J Am Soc Nephrol. 2019 Feb 08; doi: 10.1681/ASN.2018101059. Epub 2019 Feb 08.

No abstract available.

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Flythe JE, Narendra JH, Hilliard T, et al. Cultivating a Research-Ready Dialysis Community. J Am Soc Nephrol. 2019;doi: 10.1681/ASN.2018101059.
Flythe, J. E., Narendra, J. H., Hilliard, T., Frazier, K., Ikeler, K., Amolegbe, A., Mitchell, D., Dorough, A., Lee, S. D., Ordish, A., Wilkie, C., Dember, L. M. (2019). Cultivating a Research-Ready Dialysis Community. Journal of the American Society of Nephrology : JASN, . https://doi.org/10.1681/ASN.2018101059
Flythe, Jennifer E, et al. "Cultivating a Research-Ready Dialysis Community." Journal of the American Society of Nephrology : JASN vol. (2019). doi: https://doi.org/10.1681/ASN.2018101059
Flythe JE, Narendra JH, Hilliard T, Frazier K, Ikeler K, Amolegbe A, Mitchell D, Dorough A, Lee SD, Ordish A, Wilkie C, Dember LM. Cultivating a Research-Ready Dialysis Community. J Am Soc Nephrol. 2019 Feb 08; doi: 10.1681/ASN.2018101059. Epub 2019 Feb 08. PMID: 30737271; PMCID: PMC6405153.
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Showing 1 to 5 of 5 entries