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Larson EB, Tachibana C, Thompson E, et al. Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthc (Amst). 2015;4(3):138-41doi: 10.1016/j.hjdsi.2015.07.005.
Larson, E. B., Tachibana, C., Thompson, E., Coronado, G. D., DeBar, L., Dember, L. M., Honda, S., Huang, S. S., Jarvik, J. G., Nelson, C., Septimus, E., Simon, G., & Johnson, K. E. (2016). Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthcare (Amsterdam, Netherlands), 4(3), 138-41. https://doi.org/10.1016/j.hjdsi.2015.07.005
Larson, Eric B, et al. "Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems." Healthcare (Amsterdam, Netherlands) vol. 4,3 (2016): 138-41. doi: https://doi.org/10.1016/j.hjdsi.2015.07.005
Larson EB, Tachibana C, Thompson E, Coronado GD, DeBar L, Dember LM, Honda S, Huang SS, Jarvik JG, Nelson C, Septimus E, Simon G, Johnson KE. Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems. Healthc (Amst). 2016 Sep;4(3):138-41. doi: 10.1016/j.hjdsi.2015.07.005. Epub 2015 Jul 29. PMID: 27637816; PMCID: PMC5027068.
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Healthc (Amst). 2016 Sep;4(3):138-41. doi: 10.1016/j.hjdsi.2015.07.005. Epub 2015 Jul 29.

Trials without tribulations: Minimizing the burden of pragmatic research on healthcare systems.

Healthcare (Amsterdam, Netherlands)

Eric B Larson, Chris Tachibana, Ella Thompson, Gloria D Coronado, Lynn DeBar, Laura M Dember, Stacey Honda, Susan S Huang, Jeffrey G Jarvik, Christine Nelson, Edward Septimus, Greg Simon, Karin E Johnson

Affiliations

  1. Group Health Research Institute, Seattle, WA, USA.
  2. Kaiser Permanente Center for Health Research, Portland, OR, USA.
  3. University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  4. Hawaii Permanente Medical Group, Mililani, HI, USA.
  5. University of California Irvine School of Medicine, Irvine CA, USA.
  6. University of Washington, Seattle, WA, USA.
  7. OCHIN, Portland, OR USA.
  8. Clinical Services Group, Hospital Corporation of America, Nashville, TN, USA.
  9. Group Health Research Institute, Seattle, WA, USA. Electronic address: [email protected].

PMID: 27637816 PMCID: PMC5027068 DOI: 10.1016/j.hjdsi.2015.07.005

Abstract

Pragmatic clinical trials are increasingly common because they have the potential to yield findings that are directly translatable to real-world healthcare settings. Pragmatic clinical trials need to integrate research into clinical workflow without placing an undue burden on the delivery system. This requires a research partnership between investigators and healthcare system representatives. This paper, organized as a series of case studies drawn from our experience in the NIH Health Care Systems Research Collaboratory, presents guidance from informational interviews of physician-scientists, health services researchers, and delivery system leaders who recently launched pragmatic clinical trials.

Copyright © 2015 Elsevier Inc. All rights reserved.

Keywords: Pragmatic trials

References

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