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Showing 1 to 12 of 30 entries
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Preoperative cardiac variables of diastolic dysfunction and clinical outcomes in lung transplant recipients.

Journal of transplantation

Yadlapati A, Lynch JP, Saggar R, Ross D, Belperio JA, Weigt S, Ardehali A, Grogan T, Yang EH, Aboulhosn J.
PMID: 24163757
J Transplant. 2013;2013:391620. doi: 10.1155/2013/391620. Epub 2013 Sep 12.

Background. Orthotopic lung transplantation is now widely performed in patients with advanced lung disease. Patients with moderate or severe ventricular systolic dysfunction are typically excluded from lung transplantation; however, there is a paucity of data regarding the prognostic significance...

The association of adipose tissue area with subclinical coronary atherosclerosis progression in men with and without HIV.

AIDS (London, England)

Sarkar S, Bhondoekhan F, Haberlen S, Palella FJ, Kingsley LA, Budoff M, Witt MD, Post WS, Brown TT.
PMID: 34870934
AIDS. 2021 Dec 01;35(15):2549-2551. doi: 10.1097/QAD.0000000000003042.

No abstract available.

A Bayesian Adaptive Design in Cancer Phase I Trials using Dose Combinations in the Presence of a Baseline Covariate.

Journal of probability and statistics

Diniz MA, Kim S, Tighiouart M.
PMID: 30906326
J Probab Stat. 2018;2018. doi: 10.1155/2018/8654173. Epub 2018 Nov 01.

A Bayesian adaptive design for dose finding of a combination of two drugs in cancer phase I clinical trials that takes into account patients heterogeneity thought to be related to treatment susceptibility is described. The estimation of the maximum...

Using animation as an information tool to advance health research literacy among minority participants.

AMIA ... Annual Symposium proceedings. AMIA Symposium

George S, Moran E, Duran N, Jenders RA.
PMID: 24551351
AMIA Annu Symp Proc. 2013 Nov 16;2013:475-84. eCollection 2013.

Lack of adequate consumer health information about clinical research contributes to health disparities among low health literate minority multicultural populations and requires appropriate methods for making information accessible. Enhancing understanding of health research can enable such minority multicultural consumers...

Characterization of Intra-myocellular Lipids using 2D Localized Correlated Spectroscopy and Abdominal Fat using MRI in Type 2 Diabetes.

Magnetic resonance insights

Srikanthan P, Singhal A, Lee CC, Nagarajan R, Wilson N, Roberts CK, Hahn TJ, Thomas MA.
PMID: 23471581
Magn Reson Insights. 2012 Oct 15;5:29-36. doi: 10.4137/MRI.S10489.

A major goal of this pilot study was to quantify intramyocellular lipids (IMCL), extramyocellular lipids (EMCL), unsaturation index (UI) and metabolites such as creatine (Cr), choline (Ch) and carnosine (Car), in the soleus muscle using two-dimensional (2D) localized correlated...

Heart rate variability as a biomarker for autonomic nervous system response differences between children with chronic pain and healthy control children.

Journal of pain research

Evans S, Seidman LC, Tsao JC, Lung KC, Zeltzer LK, Naliboff BD.
PMID: 23788839
J Pain Res. 2013 Jun 12;6:449-57. doi: 10.2147/JPR.S43849. Print 2013.

Studies in adults have demonstrated a relationship between lowered heart rate variability (HRV) and poor health. However, less is known about the role of autonomic arousal in children's well-being. The aim of the current study was to examine resting...

GITR agonist enhances vaccination responses in lung cancer.

Oncoimmunology

Zhu LX, Davoodi M, Srivastava MK, Kachroo P, Lee JM, St John M, Harris-White M, Huang M, Strieter RM, Dubinett S, Sharma S.
PMID: 26137407
Oncoimmunology. 2015 Apr 27;4(4):e992237. doi: 10.4161/2162402X.2014.992237. eCollection 2015 Apr.

An immune tolerant tumor microenvironment promotes immune evasion of lung cancer. Agents that antagonize immune tolerance will thus aid the fight against this devastating disease. Members of the tumor necrosis factor receptor (TNFR) family modulate the magnitude, duration and...

Cystatin C-based renal function changes after antiretroviral initiation: a substudy of a randomized trial.

Open forum infectious diseases

Gupta SK, Kitch D, Tierney C, Daar ES, Sax PE, Melbourne K, Ha B, McComsey GA.
PMID: 25734077
Open Forum Infect Dis. 2014 Apr 16;1(1):ofu003. doi: 10.1093/ofid/ofu003. eCollection 2014 Mar.

BACKGROUND: The effects of antiretrovirals on cystatin C-based renal function estimates are unknown.METHODS: We analyzed changes in renal function using creatinine and cystatin C-based estimating equations in 269 patients in A5224s, a substudy of study A5202, in which treatment-naive...

Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study.

American journal of hematology

Jo Hodonsky C, Schurmann C, Schick UM, Kocarnik J, Tao R, van Rooij FJ, Wassel C, Buyske S, Fornage M, Hindorff LA, Floyd JS, Ganesh SK, Lin DY, North KE, Reiner AP, Loos RJ, Kooperberg C, Avery CL.
PMID: 29905378
Am J Hematol. 2018 Jun 15; doi: 10.1002/ajh.25161. Epub 2018 Jun 15.

Red blood cell (RBC) traits provide insight into a wide range of physiological states and exhibit moderate to high heritability, making them excellent candidates for genetic studies to inform underlying biologic mechanisms. Previous RBC trait genome-wide association studies were...

Alcohol Cue-Induced Ventral Striatum Activity Predicts Subsequent Alcohol Self-Administration.

Alcoholism, clinical and experimental research

Lim AC, Green R, Grodin EN, Venegas A, Meredith LR, Donato S, Burnette E, Ray LA.
PMID: 32406553
Alcohol Clin Exp Res. 2020 Jun;44(6):1224-1233. doi: 10.1111/acer.14342. Epub 2020 May 14.

BACKGROUND: Human laboratory paradigms are a pillar in medication development for alcohol use disorders (AUD). Neuroimaging paradigms, in which individuals are exposed to cues that elicit neural correlates of alcohol craving (e.g., mesocorticolimbic activation), are increasingly utilized to test...

Inflammatory bowel disease.

International journal of inflammation

Sachar DB, Jewell D, Gasche C, Braun J.
PMID: 22536542
Int J Inflam. 2012;2012:341052. doi: 10.1155/2012/341052. Epub 2012 Mar 27.

No abstract available.

Rare and low-frequency exonic variants and gene-by-smoking interactions in pulmonary function.

Scientific reports

Yang T, Jackson VE, Smith AV, Chen H, Bartz TM, Sitlani CM, Psaty BM, Gharib SA, O'Connor GT, Dupuis J, Xu J, Lohman K, Liu Y, Kritchevsky SB, Cassano PA, Flexeder C, Gieger C, Karrasch S, Peters A, Schulz H, Harris SE, Starr JM, Deary IJ, Manichaikul A, Oelsner EC, Barr RG, Taylor KD, Rich SS, Bonten TN, Mook-Kanamori DO, Noordam R, Li-Gao R, Jarvelin MR, Wielscher M, Terzikhan N, Lahousse L, Brusselle G, Weiss S, Ewert R, Gläser S, Homuth G, Shrine N, Hall IP, Tobin M, London SJ, Wei P, Morrison AC.
PMID: 34588469
Sci Rep. 2021 Sep 29;11(1):19365. doi: 10.1038/s41598-021-98120-7.

Genome-wide association studies have identified numerous common genetic variants associated with spirometric measures of pulmonary function, including forced expiratory volume in one second (FEV

Showing 1 to 12 of 30 entries