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Showing 1 to 12 of 44 entries
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The Mobile Insulin Titration Intervention (MITI) for Insulin Glargine Titration in an Urban, Low-Income Population: Randomized Controlled Trial Protocol.

JMIR research protocols

Levy N, Moynihan V, Nilo A, Singer K, Bernik LS, Etiebet MA, Fang Y, Cho J, Natarajan S.
PMID: 25794243
JMIR Res Protoc. 2015 Mar 13;4(1):e31. doi: 10.2196/resprot.4206.

BACKGROUND: Patients on insulin glargine typically visit a clinician to obtain advice on how to adjust their insulin dose. These multiple clinic visits can be costly and time-consuming, particularly for low-income patients. It may be feasible to achieve insulin...

Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells.

Oncotarget

Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, Tsirigos A, Heguy A, Chesler M, Barcellos-Hoff MH, Snuderl M, Placantonakis DG.
PMID: 29029402
Oncotarget. 2017 May 23;8(39):64932-64953. doi: 10.18632/oncotarget.18117. eCollection 2017 Sep 12.

Glioblastoma (GBM) stem cells (GSCs) reside in both hypoxic and vascular microenvironments within tumors. The molecular mechanisms that allow GSCs to occupy such contrasting niches are not understood. We used patient-derived GBM cultures to identify GSC subtypes with differential...

The Effect of a Vegan versus AHA DiEt in Coronary Artery Disease (EVADE CAD) trial: study design and rationale.

Contemporary clinical trials communications

Shah B, Ganguzza L, Slater J, Newman JD, Allen N, Fisher E, Larigakis J, Ujueta F, Gianos E, Guo Y, Woolf K.
PMID: 29333503
Contemp Clin Trials Commun. 2017 Dec;8:90-98. doi: 10.1016/j.conctc.2017.09.003. Epub 2017 Sep 14.

BACKGROUND: Multiple studies demonstrate the benefit of a vegan diet on cardiovascular risk factors when compared to no intervention or usual dietary patterns. The aim of this study is to evaluate the effect of a vegan diet versus the...

Eye Control Deficits Coupled to Hand Control Deficits: Eye-Hand Incoordination in Chronic Cerebral Injury.

Frontiers in neurology

Rizzo JR, Fung JK, Hosseini M, Shafieesabet A, Ahdoot E, Pasculli RM, Rucker JC, Raghavan P, Landy MS, Hudson TE.
PMID: 28769866
Front Neurol. 2017 Jul 17;8:330. doi: 10.3389/fneur.2017.00330. eCollection 2017.

It is widely accepted that cerebral pathology can impair ocular motor and manual motor control. This is true in indolent and chronic processes, such as neurodegeneration and in acute processes such as stroke or those secondary to neurotrauma. More...

A Novel Sonification Approach to Support the Diagnosis of Alzheimer's Dementia.

Frontiers in neurology

Gionfrida L, Roginska A.
PMID: 29270150
Front Neurol. 2017 Dec 07;8:647. doi: 10.3389/fneur.2017.00647. eCollection 2017.

Alzheimer's disease is the most common neurodegenerative form of dementia that steadily worsens and eventually leads to death. Its set of symptoms include loss of cognitive function and memory decline. Structural and functional imaging methods such as CT, MRI,...

Detection of Cerebrovascular Loss in the Normal Aging C57BL/6 Mouse Brain Using .

Frontiers in aging neuroscience

Hill LK, Hoang DM, Chiriboga LA, Wisniewski T, Sadowski MJ, Wadghiri YZ.
PMID: 33192479
Front Aging Neurosci. 2020 Oct 20;12:585218. doi: 10.3389/fnagi.2020.585218. eCollection 2020.

Microvascular rarefaction, or the decrease in vascular density, has been described in the cerebrovasculature of aging humans, rats, and, more recently, mice in the presence and absence of age-dependent diseases. Given the wide use of mice in modeling age-dependent...

Design, implementation, and evaluation of PINDAR, a novel short program on GCP for academic medical center principal investigators conducting human subject research.

Journal of clinical and translational science

Plottel CS, Mannon L, More FG, Katz SD, Hochman JS.
PMID: 31404275
J Clin Transl Sci. 2018 Dec;2(6):343-349. doi: 10.1017/cts.2019.5.

The

Abnormal cholesterol is associated with prefrontal white matter abnormalities among obese adults, a diffusion tensor imaging study.

The neuroradiology journal

Cohen JI, Cazettes F, Convit A.
PMID: 22163070
Neuroradiol J. 2011 Nov 15;1(21):989-997.

The brain is the most cholesterol-rich organ in the body. Although most of the cholesterol in the brain is produced endogenously, some studies suggest that systemic cholesterol may be able to enter the brain. We investigated whether abnormal cholesterol...

Obesity, orbitofrontal structure and function are associated with food choice: a cross-sectional study.

BMJ open

Cohen JI, Yates KF, Duong M, Convit A.
PMID: 22021878
BMJ Open. 2011 Jan 01;1(2):e000175. doi: 10.1136/bmjopen-2011-000175.

Objectives Obesity is on the rise in the US and is linked to the development of type 2 diabetes and cardiovascular disease. Emerging evidence over the last decade suggests that obesity may also adversely affect executive function and brain...

Letter to the editor regarding: Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective.

Alzheimer's & dementia (Amsterdam, Netherlands)

Kamer AR, Janal MN, de Leon M.
PMID: 27239519
Alzheimers Dement (Amst). 2015 Sep 02;1(4):385-6. doi: 10.1016/j.dadm.2015.08.003. eCollection 2015 Dec.

No abstract available.

Association of diabetes with tooth loss in Hispanic/Latino adults: findings from the Hispanic Community Health Study/Study of Latinos.

BMJ open diabetes research & care

Greenblatt AP, Salazar CR, Northridge ME, Kaplan RC, Taylor GW, Finlayson TL, Qi Q, Badner V.
PMID: 27239319
BMJ Open Diabetes Res Care. 2016 May 12;4(1):e000211. doi: 10.1136/bmjdrc-2016-000211. eCollection 2016.

OBJECTIVES: To investigate the association between diabetes mellitus and missing teeth in Hispanic/Latino adults from diverse heritage groups who reside in the USA.RESEARCH DESIGN AND METHODS: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, population-based study...

Regulation of inflammation by adenosine.

Frontiers in immunology

Haskó G, Cronstein B.
PMID: 23580000
Front Immunol. 2013 Apr 08;4:85. doi: 10.3389/fimmu.2013.00085. eCollection 2013.

Adenosine, a purine nucleoside generated by the dephosphorylation of adenine nucleotides, is a potent endogenous physiologic and pharmacologic regulator of many functions. Adenosine was first reported to inhibit the inflammatory actions of neutrophils nearly 30 years ago and since...

Showing 1 to 12 of 44 entries