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Showing 1 to 12 of 771 entries
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Vasoconstrictor effect of Africanized honeybee (Apis mellifera L.) venom on rat aorta.

The journal of venomous animals and toxins including tropical diseases

Sousa PC, Brito TS, Freire DS, Ximenes RM, Magalhães PJ, Monteiro HS, Alves RS, Martins AM, Toyama DO, Toyama MH.
PMID: 24066982
J Venom Anim Toxins Incl Trop Dis. 2013 Sep 25;19(1):24. doi: 10.1186/1678-9199-19-24.

BACKGROUND: Apis mellifera stings are a problem for public health worldwide, particularly in Latin America due to the aggressiveness of its Africanized honeybees. Massive poisoning by A. mellifera venom (AmV) affects mainly the cardiovascular system, and several works have...

Diagnosis and Treatment of Childhood Migraine.

Current treatment options in neurology

Merison K, Jacobs H.
PMID: 27704257
Curr Treat Options Neurol. 2016 Nov;18(11):48. doi: 10.1007/s11940-016-0431-4.

OPINION STATEMENT: While the diagnosis of migraine in children is generally straightforward, treatment can seem complex with a number of medication choices, many of which are used "off label." Patients with intermittent migraines can often be managed with ibuprofen...

Analgesia Synergism of Essential Oil from Pericarp of Zanthoxylum schinifolium and Verapamil.

Evidence-based complementary and alternative medicine : eCAM

Wu G, Wu H.
PMID: 25114705
Evid Based Complement Alternat Med. 2014;2014:505876. doi: 10.1155/2014/505876. Epub 2014 Jul 08.

Objective. To evaluate the synergistic analgesic effect of essential oil of Zanthoxylum schinifolium Sieb. et Zucc. (EOZ) and verapamil (Ver). Method. The qualitative and quantitative composition of EOZ were determined with gas chromatography/Mass spectrometer. The interaction between EOZ and...

The putative P-gp inhibitor telmisartan does not affect the transcellular permeability and cellular uptake of the calcium channel antagonist verapamil in the P-glycoprotein expressing cell line MDCK II MDR1.

Pharmacology research & perspectives

Saaby L, Tfelt-Hansen P, Brodin B.
PMID: 26171231
Pharmacol Res Perspect. 2015 Aug;3(4):e00151. doi: 10.1002/prp2.151. Epub 2015 Jun 11.

Verapamil is used in high doses for the treatment of cluster headache. Verapamil has been described as a P-glycoprotein (P-gp, ABCB1) substrate. We wished to evaluate in vitro whether co administration of a P-gp inhibitor with verapamil could be...

Evaluation of the antioxidant properties of the angiotensin-converting enzyme inhibitor, captopril and the nucleotide enhancing agent, acadesine.

Redox report : communications in free radical research

Wasil M, Kelly FJ.
PMID: 27405835
Redox Rep. 1995 Nov;1(5):361-7. doi: 10.1080/13510002.1995.11747012.

The angiotensin-converting enzyme inhibitor, captopril and the nucleotide enhancing agent, acadesine, protect myocardial tissue from ischaemia/reperfusion-induced injury. Although both drugs have well established, independent mechanisms of cardiac protection, they may also have antioxidant activity which could contribute to their...

Injectable therapy for Peyronie's disease.

Translational andrology and urology

Chong W, Tan RB.
PMID: 27298778
Transl Androl Urol. 2016 Jun;5(3):310-7. doi: 10.21037/tau.2016.03.15.

Peyronie's disease is a disfiguring and psychologically devastating disease, which continues to pose a significant clinical conundrum to the attending doctor. Many forms of therapy have been trialled but results have been inconsistent at best. Non-surgical therapy revolves around...

Verapamil suppresses cardiac alternans and ventricular arrhythmias in acute myocardial ischemia via ryanodine receptor inhibition.

American journal of translational research

Deng YL, Zhao JY, Yao JH, Tang Q, Zhang L, Zhou HL, Zhang CT, Lv JG, Quan XQ.
PMID: 28670363
Am J Transl Res. 2017 Jun 15;9(6):2712-2722. eCollection 2017.

T-wave alternans (TWA) is a potent arrhythmia substrate under the conditions of acute myocardial ischemia. Abnormal intracellular calcium cycling contributes to the genesis of cardiac alternans. Ryanodine receptor (RyR) is a pivotal Ca

Local Intracoronary Eptifibatide versus Mechanical Aspiration in Patients with Acute ST-Elevation Myocardial Infarction.

International journal of vascular medicine

Hamza MA, Galal A, Suweilam S, Ismail M.
PMID: 24987529
Int J Vasc Med. 2014;2014:294065. doi: 10.1155/2014/294065. Epub 2014 Jun 03.

Objectives. We compared local delivery of intracoronary eptifibatide via perfusion catheter to thrombus aspiration in primary PCI. Background. Perfusion catheter increases local concentration of the drugs at the culprit site and prolongs their residency time. Methods. 75 patients with...

Comparison of the species-sensitive effects of different dosages of calcium and verapamil on gentamicin-induced nephrotoxicity in rats and rabbits.

Toxicology international

Patil AN, Arora T, Desai A, Tripathi CD.
PMID: 25948958
Toxicol Int. 2014 Sep-Dec;21(3):225-31. doi: 10.4103/0971-6580.155320.

AIM: To compare the effects of different dosages of calcium and verapamil on gentamicin-induced nephrotoxicity in rats and rabbits.MATERIALS AND METHODS: Rabbits and rats of either sex in weight range of 1.5-2.5 kg and 175-225 g, respectively were used...

Recurrent stereotyped episodes in cerebral amyloid angiopathy: response to migraine prophylaxis in two patients.

Cerebrovascular diseases extra

Paterson RW, Uchino K, Emsley HC, Pullicino P.
PMID: 23741226
Cerebrovasc Dis Extra. 2013 May 18;3(1):81-4. doi: 10.1159/000347114. Print 2013 Jan.

BACKGROUND: Cerebral amyloid angiopathy (CAA) typically presents with cognitive decline or symptomatic intracerebral hemorrhage, but episodes of recurrent stereotyped limb attacks have also been reported.METHODS: Retrospective review of the medical records of 4 patients referred to the general neurology...

The Novel Development of an Experimental Model of Dihydropyridine Calcium Channel Blocker Poisoning using Intravenous Amlodipine.

International journal of cardiovascular research

Jang D, Donovan S, Bania T, Nelson L, Hoffman R, Chu J.
PMID: 24416727
Int J Cardiovasc Res. 2013 Mar 29;2(2):1000121.

BACKGROUND: Cardiovascular drug poisoning remains a leading cause of fatality. Within this class, calcium channel blockers (CCBs) account for the majority of deaths. CCBs are typically categorized as dihydropyridines (i.e. amlodipine or nifedipine) versus the non-dihydropyridine (i.e. verapamil and...

A double-blind comparative study of clinical efficacy of verapamil versus lithium in acute mania.

International journal of psychiatry in clinical practice

Pal Singh G.
PMID: 24937719
Int J Psychiatry Clin Pract. 2008;12(4):303-8. doi: 10.1080/13651500802209670.

Objectives. The importance of intracellular calcium ions to processes that may be involved in mania and the calcium antagonist action of mood stabilizers suggest a role of verapamil in the treatment of mania. This study was undertaken to compare...

Showing 1 to 12 of 771 entries