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Showing 1 to 12 of 63 entries
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The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS, and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba.

Evidence-based complementary and alternative medicine : eCAM

Zhang X, Wang Y, Liang Q, Ma Z, Xiao C, Tan H, Gao Y.
PMID: 25024734
Evid Based Complement Alternat Med. 2014;2014:892797. doi: 10.1155/2014/892797. Epub 2014 Jun 12.

The eighteen incompatible medicaments is an important theory in traditional Chinese medicine. The theory suggests that drugs in the eighteen incompatible medicaments can be toxic when used together. Veratrum nigrum L. and Radix paeoniae alba belong to the eighteen...

Release of(14)C-adenine derivatives from cerebral cortical slices: Effect of phenytoin and phenobarbital.

Neurochemical research

Lewin E, Bleck V.
PMID: 24271574
Neurochem Res. 1976 Aug;1(4):429-35. doi: 10.1007/BF00966234.

Both ouabain, 0.1 mM, and veratridine, 0.05 mM, increased the release of(14)C-labeled compounds from rat cortical slices prelabeled with(14)C-adenine and incubated in vitro. The increment in radioactivity released by both depolarizing agents was almost entirely a result of increases...

Sites of [3H]taurine Uptake in the Rat Substantia Nigra in Relation to the Release of Taurine from the Striatonigral Pathway.

The European journal of neuroscience

Della Corte L, Bolam JP, Clarke DJ, Parry DM, Smith AD.
PMID: 12106102
Eur J Neurosci. 1990 Jan;2(1):50-61. doi: 10.1111/j.1460-9568.1990.tb00380.x.

The autoradiographic localization of radiolabelled taurine taken up in the rat substantia nigra in vivo together with conditions of release of the [3H]taurine taken up into brain slices were studied to determine whether they are consistent with the hypothesis...

Inhibition of the Sodium Channel by SK&F 96365, an Inhibitor of the Receptor-Operated Calcium Channel, in Mouse Diaphragm.

Journal of biomedical science

Hong SJ, Lin WW, Chang CC.
PMID: 11725023
J Biomed Sci. 1994 Jun;1(3):172-178. doi: 10.1007/BF02253347.

The effects of SK&F 96365, a blocker of the receptor-operated Ca(2+) channel, on contractilities and the Na(+) channel of mouse diaphragm were studied. SK&F 96365 (10-50 &mgr;M) reversibly inhibited twitches, tetanic contractions and muscle and nerve action potentials. The...

Membrane properties of a human neuroblastoma.

Neuroscience letters

Kuramoto T, Perez-Polo JR, Haber B.
PMID: 19604936
Neurosci Lett. 1977 Mar;4(3):151-9. doi: 10.1016/0304-3940(77)90130-6.

The electrical properties of the SK-N-SH human neuroblastoma cell were studied by standard intracellular recording techniques; the average resting membrane potential was -21 +/- 11 mV, with a few cells showing mebrane potentials greater than - 40 mV. Under...

Provinol inhibits catecholamine secretion from the rat adrenal medulla.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Lee JH, Seo YS, Lim DY.
PMID: 19885042
Korean J Physiol Pharmacol. 2009 Jun;13(3):229-39. doi: 10.4196/kjpp.2009.13.3.229. Epub 2009 Jun 30.

The aim of the present study was to examine the effect of provinol, which is a mixture of polyphenolic compounds from red wine, on the secretion of catecholamines (CA) from isolated perfused rat adrenal medulla, and to elucidate its...

Inhibitory effects of olmesartan on catecholamine secretion from the perfused rat adrenal medulla.

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology

Lim HJ, Kim SY, Lim DY.
PMID: 20827339
Korean J Physiol Pharmacol. 2010 Aug;14(4):241-8. doi: 10.4196/kjpp.2010.14.4.241. Epub 2010 Aug 31.

The present sutdy aimed to determine whether olmesartan, an angiotensin II (Ang II) type 1 (AT(1)) receptor blocker, can influence the CA release from the isolated perfused model of the rat adrenal medulla. Olmesartan (5~50 µM) perfused into an...

Release of d-[(3)H]aspartic acid from the rat substantia nigra: effect of veratridine-evoked depolarization and cortical ablation.

Neurochemistry international

Abarca J, Bustos G.
PMID: 20492918
Neurochem Int. 1985;7(2):229-36. doi: 10.1016/0197-0186(85)90109-3.

The spontaneous and veratridine-evoked release of radioactive d-aspartic acid, previously taken up by rat substantia nigra slices, was studied by using a superfusion system. Veratridine (25 ?M, 1 min) markedly produced a 14-fold increase in d-[(3)H]aspartic acid release from...

The sodium channel in membranes of electroplax. Binding of batrachotoxinin-a [(3)H]benzoate to particulate preparations from electric eel (electrophorus).

Neurochemistry international

McNeal ET, Daly JW.
PMID: 20493151
Neurochem Int. 1986;9(4):487-92. doi: 10.1016/0197-0186(86)90139-7.

Batrachotoxinin-A [(3)H]benzoate ([(3)H]BTX-B) binds specifically and with high affinity (K(D) 48 nM) to sites (B(max) 2.1 pmol/mg protein) associated with voltage-dependent sodium channels in rodent brain vesicular preparations. High affinity binding requires the presence of scorpion (Leiurus) venom and...

6-Benzoylheteratisine - a class-I antiarrhythmic substance from Aconitum tanguticum (Maxim.) Stapf.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Heubach JF, Heer F, Wilhelm D, Peters T.
PMID: 23195397
Phytomedicine. 1997 Jun;4(2):109-15. doi: 10.1016/S0944-7113(97)80053-0.

The antiarrhythmic action of 6-benzoylheteratisine (6-bh), a C(19) diterpenoid alkaloid from Aconitum tanguticum (Maxim.) Stapf was investigated in left and right guinea pig isolated atria. Furthermore, possible effects on transmembrane action potential of isolated papillary muscles were studied using...

Interactions between the hypothalamo-pituitary adrenal axis and the thymus in the rat: a role for corticotrophin in the control of thymulin release.

Journal of neuroendocrinology

Buckingham JC, Safieh B, Singh S, Arduino LA, Cover PO, Kendall MD.
PMID: 21554609
J Neuroendocrinol. 1992 Jun;4(3):295-301. doi: 10.1111/j.1365-2826.1992.tb00171.x.

Our recent observations in man suggested that the secretion of the thymic peptide, thymulin, is influenced by hormones of the pituitary-adrenal axis. In the present study, we have used the rat as a model in order to examine 1)...

Beta Amyloid Differently Modulate Nicotinic and Muscarinic Receptor Subtypes which Stimulate in vitro and in vivo the Release of Glycine in the Rat Hippocampus.

Frontiers in pharmacology

Zappettini S, Grilli M, Olivero G, Mura E, Preda S, Govoni S, Salamone A, Marchi M.
PMID: 22866037
Front Pharmacol. 2012 Jul 27;3:146. doi: 10.3389/fphar.2012.00146. eCollection 2012.

Using both in vitro (hippocampal synaptosomes in superfusion) and in vivo (microdialysis) approaches we investigated whether and to what extent β amyloid peptide 1-40 (Aβ 1-40) interferes with the cholinergic modulation of the release of glycine (GLY) in the...

Showing 1 to 12 of 63 entries