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Showing 1 to 12 of 29 entries
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Complexities in understanding and addressing the serious public health issues related to the nonmedical use of prescription drugs.

Addictive behaviors

Arria AM, Compton WM.
PMID: 27639956
Addict Behav. 2017 Feb;65:215-217. doi: 10.1016/j.addbeh.2016.09.002. Epub 2016 Sep 09.

No abstract available.

Myristic acid hitchhiking on sigma-1 receptor to fend off neurodegeneration.

Receptors & clinical investigation

Ciesielski J, Su TP, Tsai SY.
PMID: 27077074
Receptors Clin Investig. 2016;3(1). doi: 10.14800/rci.1114.

Neurodegenerative diseases are linked to tauopathy as a result of cyclin dependent kinase 5 (cdk5) binding to its p25 activator instead of its p35 activator and becoming over-activated. The overactive complex stimulates the hyperphosphorylation of tau proteins, leading to...

Neuroepigenomics: Resources, Obstacles, and Opportunities.

Neuroepigenetics

Satterlee JS, Beckel-Mitchener A, Little R, Procaccini D, Rutter JL, Lossie AC.
PMID: 25722961
Neuroepigenetics. 2015 Jan 01;1:2-13. doi: 10.1016/j.nepig.2014.10.001.

Long-lived post-mitotic cells, such as the majority of human neurons, must respond effectively to ongoing changes in neuronal stimulation or microenvironmental cues through transcriptional and epigenomic regulation of gene expression. The role of epigenomic regulation in neuronal function is...

Reenvisioning Clinical Science: Unifying the Discipline to Improve the Public Health.

Clinical psychological science : a journal of the Association for Psychological Science

Onken LS, Carroll KM, Shoham V, Cuthbert BN, Riddle M.
PMID: 25821658
Clin Psychol Sci. 2014 Jan 01;2(1):22-34. doi: 10.1177/2167702613497932.

We present a vision of clinical science, based on a conceptual framework of intervention development endorsed by the Delaware Project. This framework is grounded in an updated stage model that incorporates basic science questions of mechanisms into every stage...

In vitro and in vivo human metabolism of a new synthetic cannabinoid NM-2201 (CBL-2201).

Forensic toxicology

Diao X, Carlier J, Zhu M, Pang S, Kronstrand R, Scheidweiler KB, Huestis MA.
PMID: 28286577
Forensic Toxicol. 2017 Jan;35(1):20-32. doi: 10.1007/s11419-016-0326-9. Epub 2016 Jul 06.

In 2014, NM-2201 (CBL-2201), a novel synthetic cannabinoid (SC), was detected by Russian and United States laboratories. It was already added to the scheduled drugs list in Japan, Sweden and Germany. Unfortunately, no human metabolism data are currently available,...

Improving drug abuse treatment delivery through adoption of harmonized electronic health record systems.

Substance abuse and rehabilitation

Ghitza UE, Sparenborg S, Tai B.
PMID: 21822398
Subst Abuse Rehabil. 2011 Jul 01;2011(2):125-131. doi: 10.2147/SAR.S23030.

A great divide currently exists between mainstream health care and specialty substance use disorders (SUD) treatment, concerning the coordination of care and sharing of medical information. Improving the coordination of SUD treatment with other disciplines of medicine will benefit...

Integrating substance abuse care with community diabetes care: implications for research and clinical practice.

Substance abuse and rehabilitation

Ghitza UE, Wu LT, Tai B.
PMID: 23378792
Subst Abuse Rehabil. 2013 Jan 01;4:3-10. doi: 10.2147/SAR.S39982. Epub 2013 Jan 11.

Cigarette smoking and alcohol use are prevalent among individuals with diabetes in the US, but little is known about screening and treatment for substance use disorders in the diabetic population. This commentary discusses the scope and clinical implications of...

Implementing drug abuse treatment services in criminal justice settings: Introduction to the CJ-DATS study protocol series.

Health & justice

Ducharme LJ, Chandler RK, Wiley TR.
PMID: 24707454
Health Justice. 2013 Dec 01;1(1):5. doi: 10.1186/2194-7899-1-5.

BACKGROUND: Despite a growing pipeline of effective clinical treatments, there remains a persistent research-to-practice gap in drug abuse services. Delivery of effective treatment services is especially lacking in the U.S. criminal justice system, where half of all incarcerated persons...

Development of Focused Transcranial Magnetic Stimulation for Rodents by Copper-Array Shields.

IEEE transactions on magnetics

Meng Q, Cherry M, Refai A, Du X, Lu H, Hong E, Yang Y, Choa FS.
PMID: 30344336
IEEE Trans Magn. 2018 May;54(5). doi: 10.1109/TMAG.2018.2796098. Epub 2018 Feb 14.

Transcranial magnetic stimulation (TMS) is one of the most widely used noninvasive brain stimulation method. It has been utilized for both treatment and diagnosis of many neural diseases, such as neuropathic pain and loss of function caused by stroke....

Potential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and Methamphetamine.

Journal of drug and alcohol research

Yasui Y, Su TP.
PMID: 27088037
J Drug Alcohol Res. 2016 Feb 20;5. doi: 10.4303/jdar/235970.

The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum membrane protein that involves a wide range of physiological functions. The Sig-1R has been shown to bind psychostimulants including cocaine and methamphetamine (METH) and thus has been implicated in the actions...

Emotional arousal enhances word repetition priming.

Cognition & emotion

Thomas LA, LaBar KS.
PMID: 26321783
Cogn Emot. 2005;19(7):1027-1047. doi: 10.1080/02699930500172440.

Three experiments were conducted to determine if emotional content increases repetition priming magnitude. In the study phase of Experiment 1, participants rated high-arousing negative (taboo) words and neutral words for concreteness. In the test phase, they made lexical decision...

Incretin Mimetics as Rational Candidates for the Treatment of Traumatic Brain Injury.

ACS pharmacology & translational science

Glotfelty EJ, Delgado T, Tovar-Y-Romo LB, Luo Y, Hoffer B, Olson L, Karlsson T, Mattson MP, Harvey B, Tweedie D, Li Y, Greig NH.
PMID: 31396586
ACS Pharmacol Transl Sci. 2019 Apr 12;2(2):66-91. doi: 10.1021/acsptsci.9b00003. Epub 2019 Feb 11.

Traumatic brain injury (TBI) is becoming an increasing public health issue. With an annually estimated 1.7 million TBIs in the United States (U.S) and nearly 70 million worldwide, the injury, isolated or compounded with others, is a major cause...

Showing 1 to 12 of 29 entries