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Showing 1 to 12 of 1350 entries
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Impact of the New Delhi metallo-beta-lactamase on beta-lactam antibiotics.

Infection and drug resistance

Zmarlicka MT, Nailor MD, Nicolau DP.
PMID: 26345624
Infect Drug Resist. 2015 Aug 24;8:297-309. doi: 10.2147/IDR.S39186. eCollection 2015.

Since the first New Delhi metallo-beta-lactamase (NDM) report in 2009, NDM has spread globally causing various types of infections. NDM-positive organisms produce in vitro resistance phenotypes to carbapenems and many other antimicrobials. It is thus surprising that the literature...

Draft Genome Sequence of NDM-1-Producing .

Genome announcements

Hoyos-Mallecot Y, Rojo-Martín MD, Bonnin RA, Creton E, Navarro Marí JM, Naas T.
PMID: 28450501
Genome Announc. 2017 Apr 27;5(17). doi: 10.1128/genomeA.00135-17.

Here, we provide the first draft genome sequence of NDM-1-producing

Complete Nucleotide Sequence of pGA45, a 140,698-bp IncFIIY Plasmid Encoding bla IMI-3-Mediated Carbapenem Resistance, from River Sediment.

Frontiers in microbiology

Dang B, Mao D, Luo Y.
PMID: 26941718
Front Microbiol. 2016 Feb 24;7:188. doi: 10.3389/fmicb.2016.00188. eCollection 2016.

Plasmid pGA45 was isolated from the sediments of Haihe River using Escherichia coli CV601 (gfp-tagged) as recipients and indigenous bacteria from sediment as donors. This plasmid confers reduced susceptibility to imipenem which belongs to carbapenem group. Plasmid pGA45 was...

Complete Genome Sequence of Carbapenemase-Producing Klebsiella pneumoniae Myophage Matisse.

Genome announcements

Provasek VE, Lessor LE, Cahill JL, Rasche ES, Kuty Everett GF.
PMID: 26430049
Genome Announc. 2015 Oct 01;3(5). doi: 10.1128/genomeA.01136-15.

Klebsiella pneumoniae is a leading cause of nosocomial infections in the United States. Due to the emergence of multidrug-resistant strains, phages targeting K. pneumoniae may be a useful alternative against this pathogen. Here, we announce the complete genome of...

Complete Genome Sequence of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Myophage Miro.

Genome announcements

Mijalis EM, Lessor LE, Cahill JL, Rasche ES, Kuty Everett GF.
PMID: 26430050
Genome Announc. 2015 Oct 01;3(5). doi: 10.1128/genomeA.01137-15.

Klebsiella pneumoniae is a Gram-negative pathogen frequently associated with antibiotic-resistant nosocomial infections. Bacteriophage therapy against K. pneumoniae may be possible to combat these infections. The following describes the complete genome sequence and key features of the pseudo-T-even K. pneumoniae...

Sensitivity to Antimicrobial Drugs of .

Open access Macedonian journal of medical sciences

Azizov IS, Lavrinenko AV, Belyaev IA, Babenko DB, Shambilova NA, Bissenova NM.
PMID: 28293307
Open Access Maced J Med Sci. 2017 Mar 15;5(1):6-8. doi: 10.3889/oamjms.2017.023. Epub 2017 Feb 08.

AIM: The article presents the current data on the sensitivity of the main 37 strains of eXtremaly Drugs Resistance (XDR) category to anti-pseudomonas drugs.MATERIAL AND METHODS: The strains were collected during the prospective multicenter study in large multidisciplinary hospitals...

Extended-spectrum β-lactamase and carbapenemase production among burn and non-burn clinical isolates of Klebsiella pneumoniae.

Iranian journal of microbiology

Eftekhar F, Naseh Z.
PMID: 26668701
Iran J Microbiol. 2015 Jun;7(3):144-9.

BACKGROUND AND OBJECTIVES: Klebsiella pneumoniae is an opportunistic pathogen responsible for up to 10% of nosocomial infections. The emergence and spread of multidrug resistant K. pneumoniae, mostly due to the production of extended-spectrum β-lactamases (ESBL) and carbapenemases, is often...

Comparative Genomics of Two ST 195 Carbapenem-Resistant Acinetobacter baumannii with Different Susceptibility to Polymyxin Revealed Underlying Resistance Mechanism.

Frontiers in microbiology

Lean SS, Yeo CC, Suhaili Z, Thong KL.
PMID: 26779129
Front Microbiol. 2016 Jan 05;6:1445. doi: 10.3389/fmicb.2015.01445. eCollection 2015.

Acinetobacter baumannii is a Gram-negative nosocomial pathogen of importance due to its uncanny ability to acquire resistance to most antimicrobials. These include carbapenems, which are the drugs of choice for treating A. baumannii infections, and polymyxins, the drugs of...

Novel Variant of New Delhi Metallo-β-lactamase, NDM-20, in .

Frontiers in microbiology

Liu Z, Li J, Wang X, Liu D, Ke Y, Wang Y, Shen J.
PMID: 29515538
Front Microbiol. 2018 Feb 21;9:248. doi: 10.3389/fmicb.2018.00248. eCollection 2018.

The spread of carbapenem-resistant Enterobacteriaceae (CRE) mediated by New Delhi metallo-β-lactamase (NDM) poses a serious challenge to clinicians and has become a major public health concern. NDM has been evolving into variants that possess different hydrolysis activity toward antibiotics,...

Review on colonization of residents and staff in Italian long-term care facilities by multidrug-resistant bacteria compared with other European countries.

Antimicrobial resistance and infection control

Aschbacher R, Pagani E, Confalonieri M, Farina C, Fazii P, Luzzaro F, Montanera PG, Piazza A, Pagani L.
PMID: 27766146
Antimicrob Resist Infect Control. 2016 Oct 11;5:33. doi: 10.1186/s13756-016-0136-1. eCollection 2016.

BACKGROUND: Rates of colonization and infection with multidrug-resistant (MDR) bacteria are increasing worldwide, in both acute care hospitals and long-term care facilities (LTCFs). Italy has one of the highest prevalence of MDR bacteria in European countries, especially with regard...

Rapid Screening for Carbapenem Resistant Organisms: Current Results and Future Approaches.

Journal of clinical and diagnostic research : JCDR

Anandan S, Damodaran S, Gopi R, Bakthavatchalam YD, Veeraraghavan B.
PMID: 26500909
J Clin Diagn Res. 2015 Sep;9(9):DM01-3. doi: 10.7860/JCDR/2015/14246.6530. Epub 2015 Sep 01.

Carbapenem producing Enterobacteriaceae (CPE) is a major public health threat. A total of 120 carbapenem resistant E.coli (n=32) and K.pneumoniae (n=88) from blood stream infections were screened for the presence of carbapenem resistant genes KPC, NDM, IMP, VIM, and...

Functional categorization of carbapenemase-mediated resistance by a combined genotyping and two-tiered Modified Hodge Test approach.

Frontiers in microbiology

Wong MH, Li Y, Chan EW, Chen S.
PMID: 25932021
Front Microbiol. 2015 Apr 16;6:293. doi: 10.3389/fmicb.2015.00293. eCollection 2015.

The functional relationship between the detection of carbapenemase activity and phenotypic resistance in Gram-negative bacterial pathogens is often ill-defined. To address this issue, we developed a two-tiered Modified Hodge Test approach for carbapenemase detection and typing, in which the...

Showing 1 to 12 of 1350 entries