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Showing 1 to 12 of 521 entries
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The subtle central effect of nutraceuticals: Is it placebo or nocebo?.

Journal of intercultural ethnopharmacology

Al-Gareeb AI.
PMID: 26401411
J Intercult Ethnopharmacol. 2015 Jul-Sep;4(3):221-3. doi: 10.5455/jice.20150403055054. Epub 2015 Apr 07.

BACKGROUND: Herbal medicines are often perceived by the general public as a "soft" alternative to Western Medicine, but the use of these substances can be risky since they can induce nocebo effect.AIM: The aim was to evaluate the nocebo...

Multivitamins and minerals modulate whole-body energy metabolism and cerebral blood-flow during cognitive task performance: a double-blind, randomised, placebo-controlled trial.

Nutrition & metabolism

Kennedy DO, Stevenson EJ, Jackson PA, Dunn S, Wishart K, Bieri G, Barella L, Carne A, Dodd FL, Robertson BC, Forster J, Haskell-Ramsay CF.
PMID: 26870152
Nutr Metab (Lond). 2016 Feb 11;13:11. doi: 10.1186/s12986-016-0071-4. eCollection 2016.

BACKGROUND: The brain is by far the most metabolically active organ in the body, with overall energy expenditure and local blood-supply closely related to neural activity. Both energy metabolism and cerebral vaso-dilation are dependent on adequate micronutrient status. This...

Stability-Indicating HPLC Assay for Determination of Idebenone in Pharmaceutical Forms.

Journal of analytical methods in chemistry

Kombath S, Balde IB, Carret S, Kabiche S, Cisternino S, Fontan JE, Schlatter J.
PMID: 26605105
J Anal Methods Chem. 2015;2015:835986. doi: 10.1155/2015/835986. Epub 2015 Oct 29.

A stability-indicating method was validated for the determination in pharmaceutical forms of idebenone a coenzyme Q10-like compound. The assay was achieved by liquid chromatography analysis using a reversed-phase C18 column and a detector set at 480 nm. The optimized...

Reversal of oxidative stress-induced apoptosis in T and B lymphocytes by Coenzyme Q10 (CoQ10).

American journal of clinical and experimental immunology

Gollapudi S, Gupta S.
PMID: 27168954
Am J Clin Exp Immunol. 2016 Apr 27;5(2):41-7. eCollection 2016.

Coenzyme Q10, (CoQ10) an electron transporter and an antioxidant, protects a variety of cell types against oxidative stress and apoptosis. However, protective effect of CoQ10 on oxidative stress-induced apoptosis in lymphocytes has not been studied in detail. In this...

Myocardial energetics and the role of micronutrients in heart failure: a critical review.

American journal of cardiovascular disease

Wong AP, Niedzwiecki A, Rath M.
PMID: 27679743
Am J Cardiovasc Dis. 2016 Sep 15;6(3):81-92. eCollection 2016.

Heart failure is a multifactorial disease with poor prognosis. There are many hypotheses regarding the cause of heart failure. Leading among them are the hemodynamic and the neuro-hormonal hypotheses. Although the energy depletion hypothesis has been fairly recent, there...

Effects of coenzyme Q.

Laboratory animal research

Song MH, Kim HN, Lim Y, Jang IS.
PMID: 28400836
Lab Anim Res. 2017 Mar;33(1):24-31. doi: 10.5625/lar.2017.33.1.24. Epub 2017 Mar 27.

The study was performed to see the effects of coenzyme Q

Supplementing .

Asian-Australasian journal of animal sciences

Bae GS, Choi A, Yeo JM, Kim JN, Song J, Kim EJ, Chang MB.
PMID: 28427254
Asian-Australas J Anim Sci. 2018 Jan;31(1):40-46. doi: 10.5713/ajas.17.0153. Epub 2017 Apr 21.

OBJECTIVE: To examine the effects of METHODS: The characteristics of RESULTS: The results of the CONCLUSION: The CoQ10 concentration in milk increased via the use of a novel DFM, and

Effectiveness of CoQ10 Oral Supplements as an Adjunct to Scaling and Root Planing in Improving Periodontal Health.

Journal of clinical and diagnostic research : JCDR

Manthena S, Rao MV, Penubolu LP, Putcha M, Harsha AV.
PMID: 26436041
J Clin Diagn Res. 2015 Aug;9(8):ZC26-8. doi: 10.7860/JCDR/2015/13486.6291. Epub 2015 Aug 01.

INTRODUCTION: Deficiency of CoQ 10 was found in human inflamed gingiva and has been found to be responsible for periodontal destruction.AIM: To evaluate the effectiveness of CoQ 10 supplementation as an adjunct to scaling and rootplaning in reducing gingival...

Coenzyme Q10 Supplementation Modulates NFκB and Nrf2 Pathways in Exercise Training.

Journal of sports science & medicine

Pala R, Orhan C, Tuzcu M, Sahin N, Ali S, Cinar V, Atalay M, Sahin K.
PMID: 26957943
J Sports Sci Med. 2016 Feb 23;15(1):196-203. eCollection 2016 Mar.

This study reports the effects of Q10, coenzyme Q10 or ubiquinone, a component of the electron transport chain in mitochondria, on nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB), inhibitors of kappa B (IκB), nuclear factor (erythroid-derived 2)-like 2...

Effectiveness of Coenzyme Q10 on echocardiographic parameters of patients with Duchenne muscular dystrophy.

Electronic physician

Salehi F, Zeinaloo A, Riasi HR, Shamloo AS.
PMID: 28461862
Electron Physician. 2017 Mar 25;9(3):3896-3904. doi: 10.19082/3896. eCollection 2017 Mar.

BACKGROUND: Myocardial damage is a common complication in patients with Duchenne muscular dystrophy (DMD) that occurs due to myocardial replacement by fat and fibrosis. In recent years, efforts have been made toward finding new pharmacological agents with fewer complications...

Fibromyalgia syndrome: metabolic and autophagic processes in intermittent cold stress mice.

Pharmacology research & perspectives

Oezel L, Then H, Jung AL, Jabari S, Bonaterra GA, Wissniowski TT, Önel SF, Ocker M, Thieme K, Kinscherf R, Di Fazio P.
PMID: 27713820
Pharmacol Res Perspect. 2016 Sep 27;4(5):e00248. doi: 10.1002/prp2.248. eCollection 2016 Oct.

Fibromyalgia is characterized by widespread musculoskeletal pain, fatigue, and depression. The aim was to analyze potential mitochondrial dysfunction or autophagy in mice after exposure to intermittent cold stress (ICS). Muscle and liver specimens were obtained from 36 mice. Lactate...

Coenzyme Q10 for the treatment of heart failure: a review of the literature.

Open heart

DiNicolantonio JJ, Bhutani J, McCarty MF, O'Keefe JH.
PMID: 26512330
Open Heart. 2015 Oct 19;2(1):e000326. doi: 10.1136/openhrt-2015-000326. eCollection 2015.

Coenzyme Q10 (CoQ10) is an endogenously synthesised and diet-supplied lipid-soluble cofactor that functions in the mitochondrial inner membrane to transfer electrons from complexes I and II to complex III. In addition, its redox activity enables CoQ10 to act as...

Showing 1 to 12 of 521 entries