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Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model.

Biomaterials research

You H, Lee EU, Kim YK, Kim BC, Park JY, Lim HC, Lee JS, Noh I, Jung UW, Choi SH.
PMID: 26331063
Biomater Res. 2014 Sep 24;18:12. doi: 10.1186/2055-7124-18-12. eCollection 2014.

BACKGROUND: The aim of this study was to evaluate the biocompatibility and resorption pattern in three-layer poly (lactide-co-glycolide) (PLGA) membrane according to the concentrations of hyaluronic acid (HA) hydrogel in rabbit calvarial defect model. Four standardized circular defects with...

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You H, Lee EU, Kim YK, et al. Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model. Biomater Res. 2014;18:12doi: 10.1186/2055-7124-18-12.
You, H., Lee, E. U., Kim, Y. K., Kim, B. C., Park, J. Y., Lim, H. C., Lee, J. S., Noh, I., Jung, U. W., & Choi, S. H. (2014). Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model. Biomaterials research, 1812. https://doi.org/10.1186/2055-7124-18-12
You, Hoon, et al. "Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model." Biomaterials research vol. 18 (2014): 12. doi: https://doi.org/10.1186/2055-7124-18-12
You H, Lee EU, Kim YK, Kim BC, Park JY, Lim HC, Lee JS, Noh I, Jung UW, Choi SH. Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model. Biomater Res. 2014 Sep 24;18:12. doi: 10.1186/2055-7124-18-12. eCollection 2014. PMID: 26331063; PMCID: PMC4552410.
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Intra-articular interleukin-1 receptor antagonist (IL1-ra) microspheres for posttraumatic osteoarthritis: in vitro biological activity and in vivo disease modifying effect.

Journal of experimental orthopaedics

Elsaid KA, Ubhe A, Shaman Z, D'Souza G.
PMID: 27539076
J Exp Orthop. 2016 Dec;3(1):18. doi: 10.1186/s40634-016-0054-4. Epub 2016 Aug 19.

BACKGROUND: Interleukin-1 receptor antagonist (IL-1 ra) can be disease-modifying in posttraumatic osteoarthritis (PTOA). One limitation is its short joint residence time. We hypothesized that IL-1 ra encapsulation in poly (lactide-co-glycolide) (PLGA) microspheres reduces IL-1 ra systemic absorption and provides...

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Elsaid KA, Ubhe A, Shaman Z, et al. Intra-articular interleukin-1 receptor antagonist (IL1-ra) microspheres for posttraumatic osteoarthritis: in vitro biological activity and in vivo disease modifying effect. J Exp Orthop. 2016;3(1):18doi: 10.1186/s40634-016-0054-4.
Elsaid, K. A., Ubhe, A., Shaman, Z., & D'Souza, G. (2016). Intra-articular interleukin-1 receptor antagonist (IL1-ra) microspheres for posttraumatic osteoarthritis: in vitro biological activity and in vivo disease modifying effect. Journal of experimental orthopaedics, 3(1), 18. https://doi.org/10.1186/s40634-016-0054-4
Elsaid, Khaled A, et al. "Intra-articular interleukin-1 receptor antagonist (IL1-ra) microspheres for posttraumatic osteoarthritis: in vitro biological activity and in vivo disease modifying effect." Journal of experimental orthopaedics vol. 3,1 (2016): 18. doi: https://doi.org/10.1186/s40634-016-0054-4
Elsaid KA, Ubhe A, Shaman Z, D'Souza G. Intra-articular interleukin-1 receptor antagonist (IL1-ra) microspheres for posttraumatic osteoarthritis: in vitro biological activity and in vivo disease modifying effect. J Exp Orthop. 2016 Dec;3(1):18. doi: 10.1186/s40634-016-0054-4. Epub 2016 Aug 19. PMID: 27539076; PMCID: PMC4990523.
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Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor.

Oncotarget

Zhang J, Shi Y, Zheng Y, Pan C, Yang X, Dou T, Wang B, Lu W.
PMID: 28978112
Oncotarget. 2017 Aug 07;8(40):68242-68251. doi: 10.18632/oncotarget.20021. eCollection 2017 Sep 15.

Functionalized nanoparticles (NPs) are usually used to enhance cellular penetration for targeted drug delivery that can improve efficacy and reduce side effects. However, it is difficult to exploit intracellular targets for similar delivery applications. Herein we describe the targeted...

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Zhang J, Shi Y, Zheng Y, et al. Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor. Oncotarget. 2017;8(40):68242-68251doi: 10.18632/oncotarget.20021.
Zhang, J., Shi, Y., Zheng, Y., Pan, C., Yang, X., Dou, T., Wang, B., & Lu, W. (2017). Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor. Oncotarget, 8(40), 68242-68251. https://doi.org/10.18632/oncotarget.20021
Zhang, Jie, et al. "Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor." Oncotarget vol. 8,40 (2017): 68242-68251. doi: https://doi.org/10.18632/oncotarget.20021
Zhang J, Shi Y, Zheng Y, Pan C, Yang X, Dou T, Wang B, Lu W. Homing in on an intracellular target for delivery of loaded nanoparticles functionalized with a histone deacetylase inhibitor. Oncotarget. 2017 Aug 07;8(40):68242-68251. doi: 10.18632/oncotarget.20021. eCollection 2017 Sep 15. PMID: 28978112; PMCID: PMC5620252.
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Homo- and Stereocomplex Crystallization of Star-Shaped Four-Armed Stereo Diblock Copolymers of Crystalline and Amorphous Poly(lactide)s: Effects of Incorporation and Position of Amorphous Blocks.

The journal of physical chemistry. B

Tsuji H, Ogawa M, Arakawa Y.
PMID: 27700096
J Phys Chem B. 2016 Oct 27;120(42):11052-11063. doi: 10.1021/acs.jpcb.6b07987. Epub 2016 Oct 17.

Star-shaped four-armed stereo diblock copolymers with an amorphous poly(dl-lactide) (PDLLA) core and a crystalline poly(l-lactide) (PLLA) or poly(d-lactide) (PDLA) shell (4-DL-L and 4-DL-D) and with a crystalline PLLA or PDLA core and amorphous PDLLA shell (4-L-DL and 4-D-DL) copolymers...

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Tsuji H, Ogawa M, Arakawa Y. Homo- and Stereocomplex Crystallization of Star-Shaped Four-Armed Stereo Diblock Copolymers of Crystalline and Amorphous Poly(lactide)s: Effects of Incorporation and Position of Amorphous Blocks. J Phys Chem B. 2016;120(42):11052-11063doi: 10.1021/acs.jpcb.6b07987.
Tsuji, H., Ogawa, M., & Arakawa, Y. (2016). Homo- and Stereocomplex Crystallization of Star-Shaped Four-Armed Stereo Diblock Copolymers of Crystalline and Amorphous Poly(lactide)s: Effects of Incorporation and Position of Amorphous Blocks. The journal of physical chemistry. B, 120(42), 11052-11063. https://doi.org/10.1021/acs.jpcb.6b07987
Tsuji, Hideto, et al. "Homo- and Stereocomplex Crystallization of Star-Shaped Four-Armed Stereo Diblock Copolymers of Crystalline and Amorphous Poly(lactide)s: Effects of Incorporation and Position of Amorphous Blocks." The journal of physical chemistry. B vol. 120,42 (2016): 11052-11063. doi: https://doi.org/10.1021/acs.jpcb.6b07987
Tsuji H, Ogawa M, Arakawa Y. Homo- and Stereocomplex Crystallization of Star-Shaped Four-Armed Stereo Diblock Copolymers of Crystalline and Amorphous Poly(lactide)s: Effects of Incorporation and Position of Amorphous Blocks. J Phys Chem B. 2016 Oct 27;120(42):11052-11063. doi: 10.1021/acs.jpcb.6b07987. Epub 2016 Oct 17. PMID: 27700096.
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Optimization of long-range order in solvent vapor annealed poly(styrene)-block-poly(lactide) thin films for nanolithography.

ACS applied materials & interfaces

Baruth A, Seo M, Lin CH, Walster K, Shankar A, Hillmyer MA, Leighton C.
PMID: 25029410
ACS Appl Mater Interfaces. 2014 Aug 27;6(16):13770-81. doi: 10.1021/am503199d. Epub 2014 Jul 16.

Detailed experiments designed to optimize and understand the solvent vapor annealing of cylinder-forming poly(styrene)-block-poly(lactide) thin films for nanolithographic applications are reported. By combining climate-controlled solvent vapor annealing (including in situ probes of solvent concentration) with comparative small-angle X-ray scattering...

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Baruth A, Seo M, Lin CH, et al. Optimization of long-range order in solvent vapor annealed poly(styrene)-block-poly(lactide) thin films for nanolithography. ACS Appl Mater Interfaces. 2014;6(16):13770-81doi: 10.1021/am503199d.
Baruth, A., Seo, M., Lin, C. H., Walster, K., Shankar, A., Hillmyer, M. A., & Leighton, C. (2014). Optimization of long-range order in solvent vapor annealed poly(styrene)-block-poly(lactide) thin films for nanolithography. ACS applied materials & interfaces, 6(16), 13770-81. https://doi.org/10.1021/am503199d
Baruth, A, et al. "Optimization of long-range order in solvent vapor annealed poly(styrene)-block-poly(lactide) thin films for nanolithography." ACS applied materials & interfaces vol. 6,16 (2014): 13770-81. doi: https://doi.org/10.1021/am503199d
Baruth A, Seo M, Lin CH, Walster K, Shankar A, Hillmyer MA, Leighton C. Optimization of long-range order in solvent vapor annealed poly(styrene)-block-poly(lactide) thin films for nanolithography. ACS Appl Mater Interfaces. 2014 Aug 27;6(16):13770-81. doi: 10.1021/am503199d. Epub 2014 Jul 16. PMID: 25029410.
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PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice.

Oncotarget

Huang N, Lu S, Liu XG, Zhu J, Wang YJ, Liu RT.
PMID: 29113362
Oncotarget. 2017 Sep 15;8(46):81001-81013. doi: 10.18632/oncotarget.20944. eCollection 2017 Oct 06.

Alzheimer's disease (AD) is the most common form of dementia, characterized by the formation of extracellular senile plaques and neuronal loss caused by amyloid β (Aβ) aggregates in the brains of AD patients. Conventional strategies failed to treat AD...

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Huang N, Lu S, Liu XG, et al. PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice. Oncotarget. 2017;8(46):81001-81013doi: 10.18632/oncotarget.20944.
Huang, N., Lu, S., Liu, X. G., Zhu, J., Wang, Y. J., & Liu, R. T. (2017). PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice. Oncotarget, 8(46), 81001-81013. https://doi.org/10.18632/oncotarget.20944
Huang, Na, et al. "PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice." Oncotarget vol. 8,46 (2017): 81001-81013. doi: https://doi.org/10.18632/oncotarget.20944
Huang N, Lu S, Liu XG, Zhu J, Wang YJ, Liu RT. PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering Aβ generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice. Oncotarget. 2017 Sep 15;8(46):81001-81013. doi: 10.18632/oncotarget.20944. eCollection 2017 Oct 06. PMID: 29113362; PMCID: PMC5655257.
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Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer.

Cancer nanotechnology

Aggarwal S, Gupta S, Pabla D, Murthy RS.
PMID: 26069510
Cancer Nanotechnol. 2013;4(6):145-157. doi: 10.1007/s12645-013-0046-3. Epub 2013 Sep 24.

The aim of the present study was the direct covalent coupling of the epidermal growth factor receptor (EGFR)-specific monoclonal antibody (mAb) to the surface of poly(lactide)-co-glycolide (PLGA)-polyethylene glycol (PEG) nanoparticles in order to achieve a cell type-specific drug carrier...

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Aggarwal S, Gupta S, Pabla D, et al. Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer. Cancer Nanotechnol. 2013;4(6):145-157doi: 10.1007/s12645-013-0046-3.
Aggarwal, S., Gupta, S., Pabla, D., & Murthy, R. S. (2013). Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer. Cancer nanotechnology, 4(6), 145-157. https://doi.org/10.1007/s12645-013-0046-3
Aggarwal, Sahil, et al. "Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer." Cancer nanotechnology vol. 4,6 (2013): 145-157. doi: https://doi.org/10.1007/s12645-013-0046-3
Aggarwal S, Gupta S, Pabla D, Murthy RS. Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer. Cancer Nanotechnol. 2013;4(6):145-157. doi: 10.1007/s12645-013-0046-3. Epub 2013 Sep 24. PMID: 26069510; PMCID: PMC4452077.
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Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization.

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society

Al-Quadeib BT, Radwan MA, Siller L, Horrocks B, Wright MC.
PMID: 26106277
Saudi Pharm J. 2015 Jul;23(3):290-302. doi: 10.1016/j.jsps.2014.11.004. Epub 2014 Nov 20.

PURPOSE: Amphotericin B (AmB) is an effective anti-fungal and anti-leishmanial agent. However, AmB has low oral bioavailability (0.3%) and adverse effects (e.g., nephrotoxicity). The objectives of this study were to improve the oral bioavailability by entrapping AmB in pegylated...

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Al-Quadeib BT, Radwan MA, Siller L, et al. Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization. Saudi Pharm J. 2014;23(3):290-302doi: 10.1016/j.jsps.2014.11.004.
Al-Quadeib, B. T., Radwan, M. A., Siller, L., Horrocks, B., & Wright, M. C. (2015). Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 23(3), 290-302. https://doi.org/10.1016/j.jsps.2014.11.004
Al-Quadeib, Bushra T, et al. "Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization." Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society vol. 23,3 (2015): 290-302. doi: https://doi.org/10.1016/j.jsps.2014.11.004
Al-Quadeib BT, Radwan MA, Siller L, Horrocks B, Wright MC. Stealth Amphotericin B nanoparticles for oral drug delivery: In vitro optimization. Saudi Pharm J. 2015 Jul;23(3):290-302. doi: 10.1016/j.jsps.2014.11.004. Epub 2014 Nov 20. PMID: 26106277; PMCID: PMC4475820.
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Active targeted nanoparticles: Preparation, physicochemical characterization and in vitro cytotoxicity effect.

Research in pharmaceutical sciences

Heidarian Sh, Derakhshandeh K, Adibi H, Hosseinzadeh L.
PMID: 26600851
Res Pharm Sci. 2015 May-Jun;10(3):241-51.

In this study, the folate decorated biodegradable poly (lactide-co-glycolide) (PLGA) nanoparticles were developed for tumor targeting of anticancer agents. Due to the overexpression of the folate receptor on tumor surface, the folate has been efficiently employed as a targeting...

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Heidarian Sh, Derakhshandeh K, Adibi H, et al. Active targeted nanoparticles: Preparation, physicochemical characterization and in vitro cytotoxicity effect. Res Pharm Sci. 2015;10(3):241-51
Heidarian, S. h., Derakhshandeh, K., Adibi, H., & Hosseinzadeh, L. (2015). Active targeted nanoparticles: Preparation, physicochemical characterization and in vitro cytotoxicity effect. Research in pharmaceutical sciences, 10(3), 241-51.
Heidarian, Sh, et al. "Active targeted nanoparticles: Preparation, physicochemical characterization and in vitro cytotoxicity effect." Research in pharmaceutical sciences vol. 10,3 (2015): 241-51.
Heidarian Sh, Derakhshandeh K, Adibi H, Hosseinzadeh L. Active targeted nanoparticles: Preparation, physicochemical characterization and in vitro cytotoxicity effect. Res Pharm Sci. 2015 May-Jun;10(3):241-51. PMID: 26600851; PMCID: PMC4621631.
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Well-Ordered Nanoporous ABA Copolymer Thin Films via Solvent Vapor Annealing, Homopolymer Blending, and Selective Etching of ABAC Tetrablock Terpolymers.

ACS applied materials & interfaces

Jackson EA, Lee Y, Radlauer MR, Hillmyer MA.
PMID: 26642426
ACS Appl Mater Interfaces. 2015 Dec 16;7(49):27331-9. doi: 10.1021/acsami.5b08856. Epub 2015 Dec 07.

Solvent vapor annealing treatments are used to control the orientation of nanostructures produced in thin films of a poly(styrene)-block-poly(isoprene)-block-poly(styrene)-block-poly((±)-lactide) (PS-PI-PS-PLA) and its blends with PLA homopolymer. The PS-PI-PS-PLA tetrablock terpolymer, previously determined to adopt a core(PLA)-shell(PS) cylindrical morphology in...

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Jackson EA, Lee Y, Radlauer MR, et al. Well-Ordered Nanoporous ABA Copolymer Thin Films via Solvent Vapor Annealing, Homopolymer Blending, and Selective Etching of ABAC Tetrablock Terpolymers. ACS Appl Mater Interfaces. 2015;7(49):27331-9doi: 10.1021/acsami.5b08856.
Jackson, E. A., Lee, Y., Radlauer, M. R., & Hillmyer, M. A. (2015). Well-Ordered Nanoporous ABA Copolymer Thin Films via Solvent Vapor Annealing, Homopolymer Blending, and Selective Etching of ABAC Tetrablock Terpolymers. ACS applied materials & interfaces, 7(49), 27331-9. https://doi.org/10.1021/acsami.5b08856
Jackson, Elizabeth A, et al. "Well-Ordered Nanoporous ABA Copolymer Thin Films via Solvent Vapor Annealing, Homopolymer Blending, and Selective Etching of ABAC Tetrablock Terpolymers." ACS applied materials & interfaces vol. 7,49 (2015): 27331-9. doi: https://doi.org/10.1021/acsami.5b08856
Jackson EA, Lee Y, Radlauer MR, Hillmyer MA. Well-Ordered Nanoporous ABA Copolymer Thin Films via Solvent Vapor Annealing, Homopolymer Blending, and Selective Etching of ABAC Tetrablock Terpolymers. ACS Appl Mater Interfaces. 2015 Dec 16;7(49):27331-9. doi: 10.1021/acsami.5b08856. Epub 2015 Dec 07. PMID: 26642426.
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Systematic design and application of unimolecular star-like block copolymer micelles: a coarse-grained simulation study.

Physical chemistry chemical physics : PCCP

Zhang X, Lin W, Wen L, Yao N, Nie S, Zhang L.
PMID: 27711540
Phys Chem Chem Phys. 2016 Sep 29;18(38):26519-26529. doi: 10.1039/c6cp05039e.

Unimolecular polymeric micelles have several features, such as thermodynamic stability, small particle size, biocompatibility, and the ability to internalize hydrophobic molecules. These micelles have recently attracted significant attention in various applications, such as nano-reactors, catalysis, and drug delivery. However,...

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Zhang X, Lin W, Wen L, et al. Systematic design and application of unimolecular star-like block copolymer micelles: a coarse-grained simulation study. Phys Chem Chem Phys. 2016;18(38):26519-26529doi: 10.1039/c6cp05039e.
Zhang, X., Lin, W., Wen, L., Yao, N., Nie, S., & Zhang, L. (2016). Systematic design and application of unimolecular star-like block copolymer micelles: a coarse-grained simulation study. Physical chemistry chemical physics : PCCP, 18(38), 26519-26529. https://doi.org/10.1039/c6cp05039e
Zhang, Xiaofang, et al. "Systematic design and application of unimolecular star-like block copolymer micelles: a coarse-grained simulation study." Physical chemistry chemical physics : PCCP vol. 18,38 (2016): 26519-26529. doi: https://doi.org/10.1039/c6cp05039e
Zhang X, Lin W, Wen L, Yao N, Nie S, Zhang L. Systematic design and application of unimolecular star-like block copolymer micelles: a coarse-grained simulation study. Phys Chem Chem Phys. 2016 Sep 29;18(38):26519-26529. doi: 10.1039/c6cp05039e. PMID: 27711540.
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Correction to "Stereocomplex Crystallization and Homocrystallization of Star-Shaped Four-Armed Stereo Diblock Poly(lactide)s with Different l-Lactyl Unit Contents: Isothermal Crystallization from the Melt".

The journal of physical chemistry. B

Tsuji H, Matsumura N, Arakawa Y.
PMID: 26986693
J Phys Chem B. 2016 Mar 31;120(12):3257. doi: 10.1021/acs.jpcb.6b02207. Epub 2016 Mar 17.

No abstract available.

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Tsuji H, Matsumura N, Arakawa Y. Correction to "Stereocomplex Crystallization and Homocrystallization of Star-Shaped Four-Armed Stereo Diblock Poly(lactide)s with Different l-Lactyl Unit Contents: Isothermal Crystallization from the Melt". J Phys Chem B. 2016;120(12):3257doi: 10.1021/acs.jpcb.6b02207.
Tsuji, H., Matsumura, N., & Arakawa, Y. (2016). Correction to "Stereocomplex Crystallization and Homocrystallization of Star-Shaped Four-Armed Stereo Diblock Poly(lactide)s with Different l-Lactyl Unit Contents: Isothermal Crystallization from the Melt". The journal of physical chemistry. B, 120(12), 3257. https://doi.org/10.1021/acs.jpcb.6b02207
Tsuji, Hideto, et al. "Correction to "Stereocomplex Crystallization and Homocrystallization of Star-Shaped Four-Armed Stereo Diblock Poly(lactide)s with Different l-Lactyl Unit Contents: Isothermal Crystallization from the Melt"." The journal of physical chemistry. B vol. 120,12 (2016): 3257. doi: https://doi.org/10.1021/acs.jpcb.6b02207
Tsuji H, Matsumura N, Arakawa Y. Correction to "Stereocomplex Crystallization and Homocrystallization of Star-Shaped Four-Armed Stereo Diblock Poly(lactide)s with Different l-Lactyl Unit Contents: Isothermal Crystallization from the Melt". J Phys Chem B. 2016 Mar 31;120(12):3257. doi: 10.1021/acs.jpcb.6b02207. Epub 2016 Mar 17. PMID: 26986693.
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