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Showing 1 to 12 of 2086 entries
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Incorporation of active metal sites in MOFs via in situ generated ligand deficient metal-linker complexes.

Chemical communications (Cambridge, England)

Barman S, Furukawa H, Blacque O, Venkatesan K, Yaghi OM, Jin GX, Berke H.
PMID: 21983899
Chem Commun (Camb). 2011 Nov 21;47(43):11882-4. doi: 10.1039/c1cc14387e. Epub 2011 Oct 10.

Two novel 3D MOFs, namely MOF-647A and MOF-648 (previously unknown trinodal 4-connected net), comprised of Cu ions and pyrazole-3,5-dicarboxylate were synthesized and characterized. A strategy for incorporating open metal sites in MOFs was investigated by utilizing an in situ...

ER.

Journal of clinical & cellular immunology

Huber S.
PMID: 26925301
J Clin Cell Immunol. 2015;6(6):1-9. doi: 10.4172/2155-9899.1000372.

OBJECTIVES: Coxsackievirus B3 (CVB3) induced myocarditis is sex dependent with males developing more severe disease than females. Previous studies had shown that sex-associated hormones determine the sex bias with testosterone and progesterone promoting myocarditis while estrogen (E2) is protective....

Crystal structure of 3-{5-[3-(4-fluoro-phen-yl)-1-isopropyl-1H-indol-2-yl]-1H-pyrazol-1-yl}indolin-2-one ethanol monosolvate.

Acta crystallographica. Section E, Crystallographic communications

Rahman ML, Kulkarni AD, Mohd Yusoff M, Kwong HC, Quah CK.
PMID: 27006787
Acta Crystallogr E Crystallogr Commun. 2016 Feb 03;72:283-6. doi: 10.1107/S2056989016001614. eCollection 2016 Mar 01.

The title indolin-2-one compound, C28H23FN4O·C2H6O, crystallizes as a 1:1 ethanol solvate. The ethanol mol-ecule is disordered over two positions with refined site occupancies of 0.560 (14) and 0.440 (14). The pyrazole ring makes dihedral angles of 84.16 (10) and...

Crystal structure of 2-[(3aS,6R)-3,3,6-trimethyl-3,3a,4,5,6,7-hexa-hydro-2H-indazol-2-yl]thia-zol-4(5H)-one.

Acta crystallographica. Section E, Crystallographic communications

Ousidi AN, Itto MY, Auhmani A, Riahi A, Daran JC, Abdelwahed A.
PMID: 27006801
Acta Crystallogr E Crystallogr Commun. 2016 Feb 17;72:334-6. doi: 10.1107/S2056989016002498. eCollection 2016 Mar 01.

The title compound, C13H19N3OS, is a new thia-zolidin-4-one derivative prepared and isolated as the pure (3aS,6R)-diastereisomer from (R)-thio-semicarbazone pulegone. It crystallized with two independent mol-ecules (A and B) in the asymmetric unit. The compound is composed of a hexhydro-indazole...

Ruthenium(ii) complexes of hemilabile pincer ligands: synthesis and catalysing the transfer hydrogenation of ketones.

Dalton transactions (Cambridge, England : 2003)

Nair AG, McBurney RT, Walker DB, Page MJ, Gatus MR, Bhadbhade M, Messerle BA.
PMID: 27539740
Dalton Trans. 2016 Sep 28;45(36):14335-42. doi: 10.1039/c6dt02459a. Epub 2016 Aug 19.

A series of Ru(ii) complexes were synthesised based on a hemilabile pyrazole-N-heterocyclic carbene (NHC)-pyrazole (C3N2H3)CH2(C3N2H2)CH2(C3N2H3) NCN pincer ligand 1. All complexes were fully characterised using single crystal X-ray crystallography and multinuclear NMR spectroscopy. Hemilabile ligands provide flexible coordination modes...

Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors.

ACS medicinal chemistry letters

Cadoni R, Pala N, Lomelino C, Mahon BP, McKenna R, Dallocchio R, Dessì A, Carcelli M, Rogolino D, Sanna V, Rassu M, Iaccarino C, Vullo D, Supuran CT, Sechi M.
PMID: 28947941
ACS Med Chem Lett. 2017 Jul 31;8(9):941-946. doi: 10.1021/acsmedchemlett.7b00229. eCollection 2017 Sep 14.

We report the synthesis, biological evaluation, and structural study of a series of substituted heteroaryl-pyrazole carboxylic acid derivatives. These compounds have been developed as inhibitors of specific isoforms of carbonic anhydrase (CA), with potential as prototypes of a new...

Combined analysis of chemical bonding in a Cu(II) dimer using QTAIM, Voronoi tessellation and Hirshfeld surface approaches.

Acta crystallographica Section B, Structural science, crystal engineering and materials

Vologzhanina AV, Kats SV, Penkova LV, Pavlenko VA, Efimov NN, Minin VV, Eremenko IL.
PMID: 26428404
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2015 Oct;71:543-54. doi: 10.1107/S2052520615015279. Epub 2015 Sep 30.

Interaction of 1-(1H-pyrazol-5-yl)ethanone oxime (H2PzOx) with copper(II) chloride in the presence of pyridine afforded a binuclear discrete [Cu2(HPzOx)2Cl2py2] complex, which was characterized by Fourier transform-IR and electron paramagnetic resonance (EPR) spectra, magnetochemistry and high-resolution X-ray diffraction experiments. Multipole refinement...

Dual role of Rh(III) catalyst enables regioselective halogenation of (electron-rich) heterocycles.

Journal of the American Chemical Society

Schröder N, Lied F, Glorius F.
PMID: 25590585
J Am Chem Soc. 2015 Feb 04;137(4):1448-51. doi: 10.1021/jacs.5b00283. Epub 2015 Jan 27.

The Rh(III)-catalyzed selective bromination and iodination of electron-rich heterocycles is reported. Kinetic investigations show that Rh plays a dual role in the bromination, catalyzing the directed halogenation and preventing the inherent halogenation of these substrates. As a result, this...

Anion-dependent self-assembly of copper coordination polymers based on pyrazole-3,5-dicarboxylate and 1,2-di(4-pyridyl)ethylene.

Dalton transactions (Cambridge, England : 2003)

Klongdee F, Boonmak J, Youngme S.
PMID: 28345695
Dalton Trans. 2017 Apr 05;46(14):4806-4815. doi: 10.1039/c7dt00406k.

By utilizing a pyrazole-3,5-dicarboxylic acid (H

Contributions of inner and outer coordination sphere bonding in determining the strength of substituted phenolic pyrazoles as copper extractants.

Dalton transactions (Cambridge, England : 2003)

Healy MR, Roebuck JW, Doidge ED, Emeleus LC, Bailey PJ, Campbell J, Fischmann AJ, Love JB, Morrison CA, Sassi T, White DJ, Tasker PA.
PMID: 26763168
Dalton Trans. 2016 Feb 21;45(7):3055-62. doi: 10.1039/c5dt04055h. Epub 2016 Jan 14.

Alkyl-substituted phenolic pyrazoles such as 4-methyl-2-[5-(n-octyl)-1H-pyrazol-3-yl]phenol (L2H) are shown to function as Cu-extractants, having similar strength and selectivity over Fe(iii) to 5-nonylsalicylaldoxime which is a component of the commercially used ACORGA® solvent extraction reagents. Substitution in the phenol ring...

Difluoromethanesulfonyl hypervalent iodonium ylides for electrophilic difluoromethylthiolation reactions under copper catalysis.

Royal Society open science

Arimori S, Matsubara O, Takada M, Shiro M, Shibata N.
PMID: 27293790
R Soc Open Sci. 2016 May 25;3(5):160102. doi: 10.1098/rsos.160102. eCollection 2016 May.

Difluoromethanesulfonyl hypervalent iodonium ylides 2 were developed as electrophilic difluoromethylthiolation reagents for a wide range of nucleophiles. Enamines, indoles, β-keto esters, silyl enol ethers and pyrroles were effectively reacted with 2 affording desired difluoromethylthio (SCF2H)-substituted compounds in good to...

Crystal structure of 5-[4-(di-methyl-amino)-phen-yl]-3-(4-methyl-phen-yl)-4,5-di-hydro-1H-pyrazole-1-carbaldehyde.

Acta crystallographica. Section E, Crystallographic communications

Adam F, Samshuddin S, Ameram N, Subramaya, Samartha L.
PMID: 26870482
Acta Crystallogr E Crystallogr Commun. 2015 Dec 09;71:o1031-2. doi: 10.1107/S2056989015023294. eCollection 2015 Dec 01.

The title compound, C19H21N3O, comprises a central pyrazole ring which is N-connected to an aldehyde group and C-connected twice to substituted benzene rings. The pyrazole ring is twisted on the C-C single bond, and the least-squares plane through this...

Showing 1 to 12 of 2086 entries