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Showing 1 to 12 of 52 entries
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Peptide hormones: Review of current and emerging uses by nasal delivery.

Advanced drug delivery reviews

Pontiroli AE.
PMID: 10837581
Adv Drug Deliv Rev. 1998 Jan 05;29(1):81-87. doi: 10.1016/s0169-409x(97)00062-8.

The family of clinically available peptide hormones (PHs) is expanding in an exponential way, and advancement of knowledge of the basic mechanisms of action of PHs has led to multiplication of the possible clinical indications of already known PHs,...

The Thioredoxin Reductase-deficient E.coli Mutant Enhances Expression into Solution of Recombinant Proteins Containing Cys Residues.

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

Tong Q, Yang YG, Zhang HT, Chen Y, Yang SL, Gong Y.
PMID: 12053185
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2001;33(1):30-34.

A 3D artificial protein, a salmon calcitonin hexa-polymer, a salmon calcitonin octo-polymer and a human prourokinase, was expressed in the cytoplasma of E.coli GJ980(trxB(-)) mutant. These recombinant proteins containedcysteine residues of different length ranging from 12-22 residues. The mutation...

Calcitonin in the prevention and therapy of osteoporotic syndromes.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Avioli LV.
PMID: 15251611
Endocr Pract. 1995 Jan-Feb;1(1):33-8. doi: 10.4158/EP.1.1.33.

It is now generally accepted that estrogen status, exercise and adequate calcium intake are the singularly most important factors which guarantee the assumption of genetically programmed peak bone mass. Physicians also recognize that estrogen replacement therapy is not only...

Efficacy and tolerability of calcitonin in the prevention and treatment of osteoporosis.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

Halkin V, Reginster JY.
PMID: 18020602
BioDrugs. 1998 Oct;10(4):295-300. doi: 10.2165/00063030-199810040-00004.

Calcitonin in general, and, more specifically, salmon calcitonin (salcatonin), has been known for 30 years to be a specific inhibitor of bone resorption. Studies have confirmed its efficacy in metabolic bone diseases characterised by excessive bone resorption, such as...

Identification of the calcitonin receptor in osteoarthritic chondrocytes.

BMC research notes

Segovia-Silvestre T, Bonnefond C, Sondergaard BC, Christensen T, Karsdal MA, Bay-Jensen AC.
PMID: 21996094
BMC Res Notes. 2011 Oct 13;4:407. doi: 10.1186/1756-0500-4-407.

BACKGROUND: Preclinical and clinical studies have shown that salmon calcitonin has cartilage protective effects in joint degenerative diseases, such as osteoarthritis (OA). However, the presence of the calcitonin receptor (CTR) in articular cartilage chondrocytes is yet to be identified....

Salmon calcitonin nasal spray : An effective alternative to estrogen therapy in select postmenopausal women.

Endocrine

Avioli LV.
PMID: 21153101
Endocrine. 1996 Oct;5(2):115-27. doi: 10.1007/BF02738696.

The efficacy and safety of estrogen replacement therapy (ERT) and salmon calcitonin in the treatment of postmenopausal osteoporosis are reviewed with special consideration given to patients for whom ERT, the primary antiresorptive therapy for osteoporosis, is not indicated, tolerable,...

Osteoprotective Effect of Enamel Matrix Derivatives on the Regeneration of Mandibular Defects in Experimentally Glucocorticoid-Induced Osteoporosis.

International journal of dentistry

Amin LE, Salama N.
PMID: 34804167
Int J Dent. 2021 Oct 13;2021:8659010. doi: 10.1155/2021/8659010. eCollection 2021.

PURPOSE: Osteoporosis is a progressive systematic skeletal illness characterized by low bone mineral density and susceptibility to fracture caused by bone resorption. MATERIALS AND METHODS: Forty healthy female white albino rats were included in this study and divided into...

Intrathecal Amylin and Salmon Calcitonin Affect Formalin Induced c-Fos Expression in the Spinal Cord of Rats.

Iranian journal of medical sciences

Khoshdel Z, Takhshid MA, Owji AA.
PMID: 25429177
Iran J Med Sci. 2014 Nov;39(6):543-51.

BACKGROUND: Amylin and Salmon Calcitonin belong to the calcitonin family of peptides and have high affinity binding sites in the rat spinal cord. The aim of this study was to characterize receptors for Amylin and Salmon Calcitonin functionally in...

Synthesis and Biological Activity of Human Calcitonin Analogue.

Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica

Yu C, Zhou GM, Li BL, Wu XF, Cui DF.
PMID: 12114969
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 1999;31(5):553-557.

The potency of salmon calcitonin (sCT) is higher but the structural homology between sCT and human calcition (hCT) is only 50%. Based on the comparison of the structure between sCT and hCT, we have designed and synthesized a hCT...

Treatment of cherubism with salmon calcitonin: a case report.

European journal of dentistry

Etoz OA, Dolanmaz D, Gunhan O.
PMID: 21912506
Eur J Dent. 2011 Aug;5(4):486-91.

Cherubism is a familial disease of the jaws which is inherited via autosomal dominant manner. Typical features of cherubism include a painless bilateral, symmetrical enlargement of the jaws, misalignment of teeth, and intra-osseous central giant cell granuloma-like lesions, which...

The biochemical and histological analysis of subcutaneous calcitonin and intramedullary methylprednisolone on bone repair after bone marrow ablation: an experimental comparative study in rats.

Journal of experimental orthopaedics

Ersozlu S, Sarisozen B, Ozer O, Adim SB, Sahin O.
PMID: 28730582
J Exp Orthop. 2017 Dec;4(1):25. doi: 10.1186/s40634-017-0100-x. Epub 2017 Jul 20.

BACKGROUND: Although, glucocorticoid (GC) and calcitonin-induced changes in bone repair have been studied previously, the exact effects of these on fracture healing remain controversial. Hence, the purpose of this experimental study is to determine biochemical and histological effects of...

Diagnosis and treatment of osteoporosis in Brazil.

Clinical calcium

Eis SR, de Souza AC.
PMID: 15775546
Clin Calcium. 2001 Apr;11(4):489-92. doi: CliCa0104489492.

The definition of Osteoporosis as proposed by WHO is widely accepted amongst Brazilian physicians. The main diagnostic tool in Brazil is Bone Densitometry (DXA). Both public and private health insurance systems reimburse the densitometry test. DXA have been used...

Showing 1 to 12 of 52 entries