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In silico identification of potential inhibitors against human 2'-5'- oligoadenylate synthetase (OAS) proteins.

Computational biology and chemistry

Gonzalez KJ, Moncada-Giraldo DM, Gutierrez JB.
PMID: 32004971
Comput Biol Chem. 2020 Apr;85:107211. doi: 10.1016/j.compbiolchem.2020.107211. Epub 2020 Jan 22.

As part of the type I IFN signaling, the 2'-5'- oligoadenylate synthetase (OAS) proteins have been involved in the progression of several non-viral diseases. Notably, OAS has been correlated with immune-modulatory functions that promote chronic inflammatory conditions, autoimmune disorders,...

Showing 1 to 1 of 1 entries