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Showing 1 to 12 of 15 entries
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Genetic polymorphisms of pharmacogenomic VIP variants in Li nationality of southern China.

Environmental toxicology and pharmacology

Ding Y, He P, He N, Li Q, Sun J, Yao J, Yi S, Xu H, Wu D, Wang X, Jin T.
PMID: 26901752
Environ Toxicol Pharmacol. 2016 Mar;42:237-42. doi: 10.1016/j.etap.2016.02.003. Epub 2016 Feb 20.

OBJECTIVES: The present study aimed to screen members of the Li nationality in southern China for genotype frequencies of VIP variants and to determine differences between the Li ethnicity and global human population samples in HapMap.METHODS: In this study,...

Unique characteristics of the Ainu population in Northern Japan.

Journal of human genetics

Jinam TA, Kanzawa-Kiriyama H, Inoue I, Tokunaga K, Omoto K, Saitou N.
PMID: 26178428
J Hum Genet. 2015 Oct;60(10):565-71. doi: 10.1038/jhg.2015.79. Epub 2015 Jul 16.

Various genetic data (classic markers, mitochondrial DNAs, Y chromosomes and genome-wide single-nucleotide polymorphisms (SNPs)) have confirmed the coexistence of three major human populations on the Japanese Archipelago: Ainu in Hokkaido, Ryukyuans in the Southern Islands and Mainland Japanese. We...

Han Chinese population data for ten STR loci in Changsha, China.

Journal of forensic sciences

Ma Y, Gong B, Xia J, Deng H, Pan Q, Li Q, Dai H, Wen S, Xia K.
PMID: 11908620
J Forensic Sci. 2002 Mar;47(2):404-5.

No abstract available.

Pharmaceutical futures: made in China?.

Nature

Cyranoski D.
PMID: 18971994
Nature. 2008 Oct 30;455(7217):1168-70. doi: 10.1038/4551168a.

No abstract available.

Simple and cost-effective 14-loci SNP assay designed for differentiation of European, East Asian and African samples.

Forensic science international. Genetics

Rogalla U, Rychlicka E, Derenko MV, Malyarchuk BA, Grzybowski T.
PMID: 25286442
Forensic Sci Int Genet. 2015 Jan;14:42-9. doi: 10.1016/j.fsigen.2014.09.009. Epub 2014 Sep 28.

During every criminal investigation, it is vital to extract as much information as possible from every piece of evidence. When it comes to DNA testing, simple short tandem repeat (STR) typing may soon become a relic because it is...

Effects of MTNR1B genetic variants on the risk of type 2 diabetes mellitus: A meta-analysis.

Molecular genetics & genomic medicine

Shen LL, Jin Y.
PMID: 30811895
Mol Genet Genomic Med. 2019 May;7(5):e611. doi: 10.1002/mgg3.611. Epub 2019 Feb 27.

BACKGROUND: Whether melatonin receptor 1B (MTNR1B) variants are associated with type 2 diabetes mellitus (T2DM) remains unclear. Therefore, we performed this meta-analysis to better explore correlations between MTNR1B variants and T2DM.METHODS: Literature research was performed in PubMed, Medline, and...

The role of mitochondrial genome in essential hypertension in a Chinese Han population.

European journal of human genetics : EJHG

Zhu HY, Wang SW, Martin LJ, Liu L, Li YH, Chen R, Wang L, Zhang ML, Benson DW.
PMID: 19401720
Eur J Hum Genet. 2009 Nov;17(11):1501-6. doi: 10.1038/ejhg.2009.63. Epub 2009 Apr 29.

Earlier genetic studies of essential hypertension have focused on nuclear genes or family-based mitochondrial screening in Caucasian and African-American pedigrees. The role of mitochondria in sporadic Chinese hypertensives is unknown. We sequenced mitochondrial genomes in 306 age- and gender-balanced...

Evaluation of non-invasive prenatal testing to detect chromosomal aberrations in a Chinese cohort.

Journal of cellular and molecular medicine

Cui W, Liu X, Zhang Y, Wang Y, Chu G, He R, Zhao Y.
PMID: 31454164
J Cell Mol Med. 2019 Nov;23(11):7873-7878. doi: 10.1111/jcmm.14614. Epub 2019 Aug 27.

The aim of this study was to evaluate the clinical feasibility of non-invasive prenatal testing (NIPT) to detect foetal copy number variations (CNVs). Next-generation sequencing for detecting foetal copy number variations (CNVs) was performed on the collected samples from...

Skeletal maturation in relation to ethnic background in children of school age: The Generation R Study.

Bone

Grgic O, Shevroja E, Dhamo B, Uitterlinden AG, Wolvius EB, Rivadeneira F, Medina-Gomez C.
PMID: 31786375
Bone. 2020 Mar;132:115180. doi: 10.1016/j.bone.2019.115180. Epub 2019 Nov 28.

Ethnicity is a well-established determinant of pediatric maturity, but the underlying genetic and environmental contributions to these ethnic differences are poorly comprehended. We aimed to evaluate the influence of ethnicity on skeletal age (SA), an assessment of pediatric maturation...

The association between hsa-miR-499 T>C polymorphism and cancer risk: a meta-analysis.

Gene

Wang L, Qian S, Zhi H, Zhang Y, Wang B, Lu Z.
PMID: 22903035
Gene. 2012 Oct 15;508(1):9-14. doi: 10.1016/j.gene.2012.08.005. Epub 2012 Aug 10.

MicroRNAs regulate gene expression at the post-transcriptional level and were involved in diverse biological and pathological processes. Single nucleotide polymorphism (SNP) which is located in the pre-miRNA may affect the processing and then influence the expression of mature miRNA....

Genetics of type 2 diabetes in European populations.

Journal of diabetes

Qi Q, Hu FB.
PMID: 22781158
J Diabetes. 2012 Sep;4(3):203-12. doi: 10.1111/j.1753-0407.2012.00224.x.

Type 2 diabetes (T2D) has become a leading health problem throughout the world. It is caused by environmental and genetic factors, as well as interactions between the two. However, until very recently, the T2D susceptibility genes have been poorly...

Ancestry inference and admixture component estimations of Chinese Kazak group based on 165 AIM-SNPs via NGS platform.

Journal of human genetics

Xie T, Shen C, Liu C, Fang Y, Guo Y, Lan Q, Wang L, Ge J, Zhou Y, Wen S, Yang Q, Zhu B.
PMID: 32081902
J Hum Genet. 2020 May;65(5):461-468. doi: 10.1038/s10038-020-0725-y. Epub 2020 Feb 21.

Predicting the biogeographical ancestries of populations and unknown individuals based on ancestry-informative markers (AIMs) has been widely applied in providing DNA clues to criminal investigations, correcting the factor of population stratification in genome-wide association studies (GWAS), and working as...

Showing 1 to 12 of 15 entries