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Showing 1 to 8 of 8 entries
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Using Synthetic Biology to Engineer Living Cells That Interface with Programmable Materials.

Journal of visualized experiments : JoVE

Heyde KC, Scott FY, Paek SH, Zhang R, Ruder WC.
PMID: 28362372
J Vis Exp. 2017 Mar 09;(121). doi: 10.3791/55300.

We have developed an abiotic-biotic interface that allows engineered cells to control the material properties of a functionalized surface. This system is made by creating two modules: a synthetically engineered strain of E. coli cells and a functionalized material...

Concise Review: The U.S. Food and Drug Administration and Regenerative Medicine.

Stem cells translational medicine

Witten CM, McFarland RD, Simek SL.
PMID: 26494784
Stem Cells Transl Med. 2015 Dec;4(12):1495-9. doi: 10.5966/sctm.2015-0098. Epub 2015 Oct 22.

UNLABELLED: Regenerative medicine (RM) is a popular term for a field of scientific and medical research. There is not one universally accepted definition of RM, but it is generally taken to mean the translation of multidisciplinary biology and engineering...

Chimeric non-antigen receptors in T cell-based cancer therapy.

Journal for immunotherapy of cancer

Guo J, Kent A, Davila E.
PMID: 34344725
J Immunother Cancer. 2021 Aug;9(8). doi: 10.1136/jitc-2021-002628.

Adoptively transferred T cell-based cancer therapies have shown incredible promise in treatment of various cancers. So far therapeutic strategies using T cells have focused on manipulation of the antigen-recognition machinery itself, such as through selective expression of tumor-antigen specific...

[Regenerative medicine using cell-sheet engineering].

Nihon Geka Gakkai zasshi

Kanai N, Yamato M, Ohki T, Yamamoto M, Okano T.
PMID: 23061365
Nihon Geka Gakkai Zasshi. 2012 Sep;113(5):435-40.

We have developed a novel strategy for regenerative medicine to recover tissue functions using temperature-responsive cell culture surfaces. To overcome the disadvantages of conventional methods such as the usage of single-cell suspension injections and biodegradable polymer scaffolds, we use...

Advances in the Production and Application of Induced Pluripotent Stem Cells.

Current stem cell research & therapy

Mortada I, Bilani N.
PMID: 28969537
Curr Stem Cell Res Ther. 2017;12(8):637-643. doi: 10.2174/1574888X12666170927115317.

BACKGROUND: Embryonic stem cells are pluripotent, meaning they have the capacity to selfrenew and to differentiate into cells of the 3 germ layers. In 2006, Takahashi et al. reprogrammed somatic cells into stem cells using exogenetic gene expression. These...

An estimate is worth about a thousand experiments: using order-of-magnitude estimates to identify cellular engineering targets.

Microbial cell factories

Metcalf KJ, Slininger Lee MF, Jakobson CM, Tullman-Ercek D.
PMID: 30165868
Microb Cell Fact. 2018 Aug 30;17(1):135. doi: 10.1186/s12934-018-0979-7.

Biotechnological processes use microbes to convert abundant molecules, such as glucose, into high-value products, such as pharmaceuticals, commodity and fine chemicals, and energy. However, from the outset of the development of a new bioprocess, it is difficult to determine...

Inducible cell-to-cell signaling for tunable dynamics in microbial communities.

Nature communications

Miano A, Liao MJ, Hasty J.
PMID: 32132536
Nat Commun. 2020 Mar 04;11(1):1193. doi: 10.1038/s41467-020-15056-8.

The last decade has seen bacteria at the forefront of biotechnological innovation, with applications including biomolecular computing, living therapeutics, microbiome engineering and microbial factories. These emerging applications are all united by the need to precisely control complex microbial dynamics...

[Promoting teaching quality by portfolio assessment in Cell Engineering classroom].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology

Yu X, Shao J, Liu X, Zhang Y, Liao Y.
PMID: 33973457
Sheng Wu Gong Cheng Xue Bao. 2021 Apr 25;37(4):1443-1449. doi: 10.13345/j.cjb.200477.

We introduce the portfolio assessment into the classroom teaching reform in the curriculum of Cell Engineering, a specialty course in bioengineering & biotechnology. We established a complete classroom evaluation system that was divided the classroom assessment system of portfolio...

Showing 1 to 8 of 8 entries