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Showing 1 to 8 of 8 entries
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The emerging role of ketogenic diets in cancer treatment.

Current opinion in clinical nutrition and metabolic care

Klement RJ.
PMID: 30531479
Curr Opin Clin Nutr Metab Care. 2019 Mar;22(2):129-134. doi: 10.1097/MCO.0000000000000540.

PURPOSE OF REVIEW: Altered glucose metabolism in cancer cells is an almost ubiquitous observation, yet hardly exploited therapeutically. However, ketogenic diets have gained growing attention in recent years as a nontoxic broad-spectrum approach to target this major metabolic difference...

Ketogenic diet in the treatment of cancer - Where do we stand?.

Molecular metabolism

Weber DD, Aminzadeh-Gohari S, Tulipan J, Catalano L, Feichtinger RG, Kofler B.
PMID: 31399389
Mol Metab. 2020 Mar;33:102-121. doi: 10.1016/j.molmet.2019.06.026. Epub 2019 Jul 27.

BACKGROUND: Cancer is one of the greatest public health challenges worldwide, and we still lack complementary approaches to significantly enhance the efficacy of standard anticancer therapies. The ketogenic diet, a high-fat, low-carbohydrate diet with adequate amounts of protein, appears...

Nonpharmacologic care for patients with Lennox-Gastaut syndrome: ketogenic diets and vagus nerve stimulation.

Epilepsia

Kossoff EH, Shields WD.
PMID: 25284035
Epilepsia. 2014 Sep;55:29-33. doi: 10.1111/epi.12546.

Individuals with Lennox-Gastaut syndrome (LGS) often do not respond to or become resistant to pharmacologic treatments. Ketogenic diets (KDs) and vagus nerve stimulation (VNS) are nonpharmacologic treatment options for these intractable patients. The classic KD, a high-fat, low-carbohydrate diet...

Use of ketogenic diet therapy in infants with epilepsy: A systematic review and meta-analysis.

Epilepsia

Lyons L, Schoeler NE, Langan D, Cross JH.
PMID: 32452537
Epilepsia. 2020 Jun;61(6):1261-1281. doi: 10.1111/epi.16543. Epub 2020 May 26.

OBJECTIVE: Ketogenic diet therapy (KDT) is a group of high-fat, low-carbohydrate diets used as an effective treatment option for children and adults with drug-resistant epilepsy. There is limited research on the efficacy of KDT in infants, where there is...

Reason for optimism: a parent's perspective.

Journal of child neurology

Abrahams J.
PMID: 23653424
J Child Neurol. 2013 Aug;28(8):1052-3. doi: 10.1177/0883073813487602. Epub 2013 May 07.

The ketogenic diet is increasing in popularity worldwide, as evidenced by this symposium. More child neurologists are prescribing it in more countries. However, the diet is still underutilized, only occasionally rising to the level of "last resort" among treatment...

The ketogenic diet in pharmacoresistant childhood epilepsy.

Expert review of neurotherapeutics

Winesett SP, Bessone SK, Kossoff EH.
PMID: 25994046
Expert Rev Neurother. 2015 Jun;15(6):621-8. doi: 10.1586/14737175.2015.1044982. Epub 2015 May 20.

Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in

Ketogenic diet.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

Dhamija R, Eckert S, Wirrell E.
PMID: 23419562
Can J Neurol Sci. 2013 Mar;40(2):158-67. doi: 10.1017/s0317167100013676.

About one third of patients with epilepsy are pharmacoresistent. For a subgroup of this population, the ketogenic diet can be highly efficacious and should be considered early. This review discusses the different types of ketogenic diet, proposed mechanism of...

Ketogenic diet, a potentially valuable therapeutic option for the management of refractory epilepsy in classical neonatal nonketotic hyperglycinemia: a case report.

European journal of clinical nutrition

Kava MP, Robertson A, Greed L, Balasubramaniam S.
PMID: 30108280
Eur J Clin Nutr. 2019 Jun;73(6):961-965. doi: 10.1038/s41430-018-0286-8. Epub 2018 Aug 14.

Nonketotic hyperglycinemia (NKH) is a devastating inborn error of glycine metabolism caused by deficient activity of the glycine cleavage enzyme. Classically, patients present with lethargy, hypotonia, myoclonic jerks, transient respiratory depression in the first week of life and often...

Showing 1 to 8 of 8 entries