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Winesett SP, Bessone SK, Kossoff EH. The ketogenic diet in pharmacoresistant childhood epilepsy. Expert Rev Neurother. 2015;15(6):621-8doi: 10.1586/14737175.2015.1044982.
Winesett, S. P., Bessone, S. K., & Kossoff, E. H. (2015). The ketogenic diet in pharmacoresistant childhood epilepsy. Expert review of neurotherapeutics, 15(6), 621-8. https://doi.org/10.1586/14737175.2015.1044982
Winesett, Steven Parrish, et al. "The ketogenic diet in pharmacoresistant childhood epilepsy." Expert review of neurotherapeutics vol. 15,6 (2015): 621-8. doi: https://doi.org/10.1586/14737175.2015.1044982
Winesett SP, Bessone SK, Kossoff EH. The ketogenic diet in pharmacoresistant childhood epilepsy. Expert Rev Neurother. 2015 Jun;15(6):621-8. doi: 10.1586/14737175.2015.1044982. Epub 2015 May 20. PMID: 25994046.
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Expert Rev Neurother. 2015 Jun;15(6):621-8. doi: 10.1586/14737175.2015.1044982. Epub 2015 May 20.

The ketogenic diet in pharmacoresistant childhood epilepsy.

Expert review of neurotherapeutics

Steven Parrish Winesett, Stacey Kordecki Bessone, Eric H W Kossoff

Affiliations

  1. Johns Hopkins All Children's Hospital, Johns Hopkins University, University of South Florida, 501 Sixth Street South, Suite 511, Saint Petersburg, FL 33701, USA.

PMID: 25994046 DOI: 10.1586/14737175.2015.1044982

Abstract

Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in <70% of patients. Surgical resection can lead to control in a select subset of patients but still leaves a significant number of patients with uncontrolled seizures. The ketogenic diet and related diets have proven to be useful in pharmacoresistant childhood epilepsy.

Keywords: GLUT-1 deficiency; MCT diet; doose syndrome; epilepsy; infantile spasms; ketogenic; lennox-gastaut syndrome; low glycemic index diet; modified atkins diet; seizures

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