Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 125 entries
Sorted by: Best Match Show Resources per page
Electrically Controllable Microparticle Synthesis and Digital Microfluidic Manipulation by Electric-Field-Induced Droplet Dispensing into Immiscible Fluids.

Scientific reports

Um T, Hong J, Im do J, Lee SJ, Kang IS.
PMID: 27534580
Sci Rep. 2016 Aug 18;6:31901. doi: 10.1038/srep31901.

The dispensing of tiny droplets is a basic and crucial process in a myriad of applications, such as DNA/protein microarray, cell cultures, chemical synthesis of microparticles, and digital microfluidics. This work systematically demonstrates droplet dispensing into immiscible fluids through...

Conductivity-based detection techniques in nanofluidic devices.

The Analyst

Harms ZD, Haywood DG, Kneller AR, Jacobson SC.
PMID: 25988434
Analyst. 2015 Jul 21;140(14):4779-91. doi: 10.1039/c5an00075k. Epub 2015 May 19.

This review covers conductivity detection in fabricated nanochannels and nanopores. Improvements in nanoscale sensing are a direct result of advances in fabrication techniques, which produce devices with channels and pores with reproducible dimensions and in a variety of materials....

On the 3-dimensional effects in etched chips for high performance liquid chromatography-separations.

Journal of chromatography. A

De Smet J, Gzil P, Baron GV, Desmet G.
PMID: 17412353
J Chromatogr A. 2007 Jun 22;1154(1):189-97. doi: 10.1016/j.chroma.2007.03.076. Epub 2007 Mar 28.

In an attempt to quantify the potential of photolithographically etched micro-pillar arrays as a perfectly ordered alternative for the packed bed of spheres, the additional band broadening originating from the top and bottom plate has been investigated using computational...

Sensor-free and Sensor-based Heart-on-a-chip Platform: A Review of Design and Applications.

Current pharmaceutical design

Wan H, Gu C, Gan Y, Wei X, Zhu K, Hu N, Wang P.
PMID: 30734671
Curr Pharm Des. 2018;24(45):5375-5385. doi: 10.2174/1381612825666190207170004.

Drug efficacy and toxicity are key factors of drug development. Conventional 2D cell models or animal models have their limitations for the efficacy or toxicity assessment in preclinical assays, which induce the failure of candidate drugs or withdrawal of...

Generation of functional cardiac microtissues in a beating heart-on-a-chip.

Methods in cell biology

Ugolini GS, Visone R, Cruz-Moreira D, Mainardi A, Rasponi M.
PMID: 30037467
Methods Cell Biol. 2018;146:69-84. doi: 10.1016/bs.mcb.2018.05.005. Epub 2018 Jul 09.

With the increasing attention on cardiovascular disorders and the current inability of pre-clinical models to accurately predict human physiology, the need for advanced and reliable heart in vitro models is paramount. Microfabrication technologies provide potential solutions in the organs-on-chip...

Decoding Network Structure in On-Chip Integrated Flow Cells with Synchronization of Electrochemical Oscillators.

Scientific reports

Jia Y, Kiss IZ.
PMID: 28387237
Sci Rep. 2017 Apr 07;7:46027. doi: 10.1038/srep46027.

The analysis of network interactions among dynamical units and the impact of the coupling on self-organized structures is a challenging task with implications in many biological and engineered systems. We explore the coupling topology that arises through the potential...

Clinically Relevant Tissue Scale Responses as New Readouts from Organs-on-a-Chip for Precision Medicine.

Annual review of analytical chemistry (Palo Alto, Calif.)

Guenat OT, Geiser T, Berthiaume F.
PMID: 31961712
Annu Rev Anal Chem (Palo Alto Calif). 2020 Jun 12;13(1):111-133. doi: 10.1146/annurev-anchem-061318-114919. Epub 2020 Jan 21.

Organs-on-chips (OOC) are widely seen as being the next generation in vitro models able to accurately recreate the biochemical-physical cues of the cellular microenvironment found in vivo. In addition, they make it possible to examine tissue-scale functional properties of...

Microfluidics for Biosynthesizing: from Droplets and Vesicles to Artificial Cells.

Small (Weinheim an der Bergstrasse, Germany)

Ai Y, Xie R, Xiong J, Liang Q.
PMID: 31603270
Small. 2020 Mar;16(9):e1903940. doi: 10.1002/smll.201903940. Epub 2019 Oct 11.

Fabrication of artificial biomimetic materials has attracted abundant attention. As one of the subcategories of biomimetic materials, artificial cells are highly significant for multiple disciplines and their synthesis has been intensively pursued. In order to manufacture robust "alive" artificial...

A valve-based microfluidic device for on-chip single cell treatments.

Electrophoresis

Sun Y, Cai B, Wei X, Wang Z, Rao L, Meng QF, Liao Q, Liu W, Guo S, Zhao X.
PMID: 30155963
Electrophoresis. 2019 Mar;40(6):961-968. doi: 10.1002/elps.201800213. Epub 2018 Sep 09.

Assays toward single-cell analysis have attracted the attention in biological and biomedical researches to reveal cellular mechanisms as well as heterogeneity. Yet nowadays microfluidic devices for single-cell analysis have several drawbacks: some would cause cell damage due to the...

Negligible-cost microfluidic device fabrication using 3D-printed interconnecting channel scaffolds.

PloS one

Felton H, Hughes R, Diaz-Gaxiola A.
PMID: 33534849
PLoS One. 2021 Feb 03;16(2):e0245206. doi: 10.1371/journal.pone.0245206. eCollection 2021.

This paper reports a novel, negligible-cost and open-source process for the rapid prototyping of complex microfluidic devices in polydimethylsiloxane (PDMS) using 3D-printed interconnecting microchannel scaffolds. These single-extrusion scaffolds are designed with interconnecting ends and used to quickly configure complex...

Fluorescence lifetime-activated droplet sorting in microfluidic chip systems.

Lab on a chip

Hasan S, Geissler D, Wink K, Hagen A, Heiland JJ, Belder D.
PMID: 30604804
Lab Chip. 2019 Jan 29;19(3):403-409. doi: 10.1039/c8lc01278d.

We present a highly efficient microfluidic fluorescence lifetime-activated droplet sorting (FLADS) approach as a novel technology for droplet manipulation in lab-on-a-chip devices. In a proof-of-concept study, we successfully applied the approach to sort droplets containing two different fluorescent compounds...

On chip optofluidic low-pressure monitoring device.

Journal of biophotonics

Chandra Roy A, Bangalore Subramanya S, Manohar Rudresh S, Venkataraman V.
PMID: 33169514
J Biophotonics. 2021 Mar;14(3):e202000381. doi: 10.1002/jbio.202000381. Epub 2020 Nov 24.

We present an on chip optofluidic surface deformable liquid Dove prism (LDP) based low-fluid flow pressure monitoring device. The unique design of the device in combination with liquid and soft solid enabled by the total internal reflection of light...

Showing 1 to 12 of 125 entries