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Showing 1 to 12 of 335 entries
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miR, miR in the Cell, Does the Virus Control Them All?.

Diabetes

Richardson SJ, Horwitz MS.
PMID: 27208018
Diabetes. 2016 Apr;65(4):823-5. doi: 10.2337/dbi15-0039.

No abstract available.

A Rapid, Amplification-Free, and Sensitive Diagnostic Assay for Single-Step Multiplexed Fluorescence Detection of MicroRNA.

Angewandte Chemie (International ed. in English)

Jin Z, Geißler D, Qiu X, Wegner KD, Hildebrandt N.
PMID: 26226913
Angew Chem Int Ed Engl. 2015 Aug 17;54(34):10024-9. doi: 10.1002/anie.201504887. Epub 2015 Jul 29.

The importance of microRNA (miRNA) dysregulation for the development and progression of diseases and the discovery of stable miRNAs in peripheral blood have made these short-sequence nucleic acids next-generation biomarkers. Here we present a fully homogeneous multiplexed miRNA FRET...

Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles.

Scientific reports

Fafián-Labora J, Lesende-Rodriguez I, Fernández-Pernas P, Sangiao-Alvarellos S, Monserrat L, Arntz OJ, van de Loo FJ, Mateos J, Arufe MC.
PMID: 28262816
Sci Rep. 2017 Mar 06;7:43923. doi: 10.1038/srep43923.

Stem cells possess significant age-dependent differences in their immune-response profile. These differences were analysed by Next-Generation Sequencing of six age groups from bone marrow mesenchymal stem cells. A total of 9,628 genes presenting differential expression between age groups were...

MiRTargetLink--miRNAs, Genes and Interaction Networks.

International journal of molecular sciences

Hamberg M, Backes C, Fehlmann T, Hart M, Meder B, Meese E, Keller A.
PMID: 27089332
Int J Mol Sci. 2016 Apr 14;17(4):564. doi: 10.3390/ijms17040564.

Information on miRNA targeting genes is growing rapidly. For high-throughput experiments, but also for targeted analyses of few genes or miRNAs, easy analysis with concise representation of results facilitates the work of life scientists. We developed miRTargetLink, a tool...

miRQuest: integration of tools on a Web server for microRNA research.

Genetics and molecular research : GMR

Aguiar RR, Ambrosio LA, Sepúlveda-Hermosilla G, Maracaja-Coutinho V, Paschoal AR.
PMID: 27050998
Genet Mol Res. 2016 Mar 28;15(1). doi: 10.4238/gmr.15016861.

This report describes the miRQuest - a novel middleware available in a Web server that allows the end user to do the miRNA research in a user-friendly way. It is known that there are many prediction tools for microRNA...

MicroRNAs and triple negative breast cancer.

International journal of molecular sciences

D'Ippolito E, Iorio MV.
PMID: 24284394
Int J Mol Sci. 2013 Nov 11;14(11):22202-20. doi: 10.3390/ijms141122202.

Triple Negative Breast Cancer (TNBC) is a very aggressive tumor subtype, which still lacks specific markers for an effective targeted therapy. Despite the common feature of negativity for the three most relevant receptors (ER, PgR and HER2), TNBC is...

The co-inertia approach in identification of specific microRNA in early and advanced atherosclerosis plaque.

Medical hypotheses

Jovanović I, Zivković M, Jovanović J, Djurić T, Stanković A.
PMID: 24815336
Med Hypotheses. 2014 Jul;83(1):11-5. doi: 10.1016/j.mehy.2014.04.019. Epub 2014 Apr 23.

MicroRNAs (miRs) are short, non-coding RNAs that regulate gene expression by absolute or partial binding to mRNA, which results in transcript degradation and translation blocking. Atherosclerosis, as a complex and progressive disease, represents one of the main causes of...

[Current status and challenges from therapeutic targeting of microRNAs].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

Ji X, Wu B, Ni C.
PMID: 26887281
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2015 Nov;33(11):869-73.

No abstract available.

Computational and bioinformatics methods for microRNA gene prediction.

Methods in molecular biology (Clifton, N.J.)

Allmer J.
PMID: 24272436
Methods Mol Biol. 2014;1107:157-75. doi: 10.1007/978-1-62703-748-8_9.

MicroRNAs (miRNAs) have attracted ever-increasing interest in recent years. Since experimental approaches for determining miRNAs are nontrivial in their application, computational methods for the prediction of miRNAs have gained popularity. Such methods can be grouped into two broad categories...

A high-throughput microRNA expression profiling system.

Methods in molecular biology (Clifton, N.J.)

Guo Y, Mastriano S, Lu J.
PMID: 25030917
Methods Mol Biol. 2014;1176:33-44. doi: 10.1007/978-1-4939-0992-6_4.

As small noncoding RNAs, microRNAs (miRNAs) regulate diverse biological functions, including physiological and pathological processes. The expression and deregulation of miRNA levels contain rich information with diagnostic and prognostic relevance and can reflect pharmacological responses. The increasing interest in...

A miRNA-driven inference model to construct potential drug-disease associations for drug repositioning.

BioMed research international

Chen H, Zhang Z.
PMID: 25789319
Biomed Res Int. 2015;2015:406463. doi: 10.1155/2015/406463. Epub 2015 Feb 19.

Increasing evidence discovered that the inappropriate expression of microRNAs (miRNAs) will lead to many kinds of complex diseases and drugs can regulate the expression level of miRNAs. Therefore human diseases may be treated by targeting some specific miRNAs with...

The role of microRNA in tumorigenesis: key players or innocent bystanders.

Journal of surgical oncology

Sini RA, Trink B, Nissan A.
PMID: 19072979
J Surg Oncol. 2009 Mar 01;99(3):135-6. doi: 10.1002/jso.21213.

No abstract available.

Showing 1 to 12 of 335 entries