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Showing 1 to 12 of 55 entries
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Recent advances in new technologies and applications for molecular TEM.

Journal of structural biology

Carragher B, Potter CS.
PMID: 26534727
J Struct Biol. 2015 Nov;192(2):145. doi: 10.1016/j.jsb.2015.10.013.

No abstract available.

Advances in electron microscopy: A qualitative view of instrumentation development for macromolecular imaging and tomography.

Archives of biochemistry and biophysics

Schröder RR.
PMID: 26032338
Arch Biochem Biophys. 2015 Sep 01;581:25-38. doi: 10.1016/j.abb.2015.05.010. Epub 2015 May 30.

Macromolecular imaging and tomography of ice embedded samples has developed into a mature imaging technology, in structural biology today widely referred to simply as cryo electron microscopy.(1) While the pioneers of the technique struggled with ill-suited instruments, state-of-the-art cryo...

Molecular imaging: current status and emerging strategies.

Clinical radiology

Pysz MA, Gambhir SS, Willmann JK.
PMID: 20541650
Clin Radiol. 2010 Jul;65(7):500-16. doi: 10.1016/j.crad.2010.03.011.

In vivo molecular imaging has a great potential to impact medicine by detecting diseases in early stages (screening), identifying extent of disease, selecting disease- and patient-specific treatment (personalized medicine), applying a directed or targeted therapy, and measuring molecular-specific effects...

Endoscopic molecular imaging of cancer.

Future oncology (London, England)

Ali T, Choyke PL, Kobayashi H.
PMID: 24106901
Future Oncol. 2013 Oct;9(10):1501-13. doi: 10.2217/fon.13.123.

White light endoscopy has proven to be a very powerful tool in oncology. There is still, however, a need for better endoscopic techniques to overcome the current limitations of white light optics. New technologies that allow higher sensitivity, improved...

Progress and Challenges for Live-cell Imaging of Genomic Loci Using CRISPR-based Platforms.

Genomics, proteomics & bioinformatics

Wu X, Mao S, Ying Y, Krueger CJ, Chen AK.
PMID: 30710789
Genomics Proteomics Bioinformatics. 2019 Apr;17(2):119-128. doi: 10.1016/j.gpb.2018.10.001. Epub 2019 Jan 30.

Chromatin conformation, localization, and dynamics are crucial regulators of cellular behaviors. Although fluorescence in situ hybridization-based techniques have been widely utilized for investigating chromatin architectures in healthy and diseased states, the requirement for cell fixation precludes the comprehensive dynamic...

Understanding Pediatric Neuroimmune Disorder Conflicts: A Neuroradiologic Approach in the Molecular Era.

Radiographics : a review publication of the Radiological Society of North America, Inc

Server Alonso A, Sakinis T, Pfeiffer HCV, Sandvig I, Barlinn J, Marthinsen PB.
PMID: 32735475
Radiographics. 2020 Sep-Oct;40(5):1395-1411. doi: 10.1148/rg.2020200032. Epub 2020 Jul 31.

Neuroimmune disorders in children are a complex group of inflammatory conditions of the central nervous system with diverse pathophysiologic mechanisms and clinical manifestations. Improvements in antibody analysis, genetics, neuroradiology, and different clinical phenotyping have expanded knowledge of the different...

Visualizing Cancer.

Cancer cell

Krummel M, Hu K, de Vries EGE, Goetz JG, Passaro D, Subramaniam S, Misteli T, Skala M, Bravo-Cordero JJ, Sutcliffe JL.
PMID: 33321083
Cancer Cell. 2020 Dec 14;38(6):753-756. doi: 10.1016/j.ccell.2020.11.014.

Imaging has had a profound impact on our ability to understand and treat cancer. We invited some experts to discuss imaging approaches that can be used in various aspects of cancer research, from investigating the complexity and diversity of...

Repurposing Molecular Imaging and Sensing for Cancer Image-Guided Surgery.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Mondal SB, O'Brien CM, Bishop K, Fields RC, Margenthaler JA, Achilefu S.
PMID: 32303598
J Nucl Med. 2020 Aug;61(8):1113-1122. doi: 10.2967/jnumed.118.220426. Epub 2020 Apr 17.

Gone are the days when medical imaging was used primarily to visualize anatomic structures. The emergence of molecular imaging (MI), championed by radiolabeled

A reflection on noninvasive molecular imaging of cancer spread to lymph nodes.

Journal of surgical oncology

He M, Yang W, Li J, Jiang Z.
PMID: 30628721
J Surg Oncol. 2019 Mar;119(4):539-540. doi: 10.1002/jso.25357. Epub 2019 Jan 10.

No abstract available.

Updates in molecular imaging techniques.

Tissue engineering and regenerative medicine

Hyun H, Cho CS.
PMID: 31624698
Tissue Eng Regen Med. 2019 Oct 01;16(5):431-432. doi: 10.1007/s13770-019-00222-x. eCollection 2019 Oct.

No abstract available.

Method of the Year: spatially resolved transcriptomics.

Nature methods

Marx V.
PMID: 33408395
Nat Methods. 2021 Jan;18(1):9-14. doi: 10.1038/s41592-020-01033-y.

No abstract available.

Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay.

SLAS discovery : advancing life sciences R & D

Willis C, Nyffeler J, Harrill J.
PMID: 32546035
SLAS Discov. 2020 Aug;25(7):755-769. doi: 10.1177/2472555220928004. Epub 2020 Jun 17.

Cell Painting is a high-throughput phenotypic profiling assay that uses fluorescent cytochemistry to visualize a variety of organelles and high-content imaging to derive a large number of morphological features at the single-cell level. Most Cell Painting studies have used...

Showing 1 to 12 of 55 entries