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Genome Editing in Human Neural Stem and Progenitor Cells.

Results and problems in cell differentiation

Bressan RB, Pollard SM.
PMID: 30209659
Results Probl Cell Differ. 2018;66:163-182. doi: 10.1007/978-3-319-93485-3_7.

Experimental tools for precise manipulation of mammalian genomes enable reverse genetic approaches to explore biology and disease. Powerful genome editing technologies built upon designer nucleases, such as CRISPR/Cas9, have recently emerged. Parallel progress has been made in methodologies for...

Nuclear and cytoplasmic localization of neural stem cell microRNAs.

RNA (New York, N.Y.)

Jeffries CD, Fried HM, Perkins DO.
PMID: 21363885
RNA. 2011 Apr;17(4):675-86. doi: 10.1261/rna.2006511. Epub 2011 Mar 01.

Although generally regarded as functional in the cytoplasm, a number of microRNAs (miRNAs) have been found in the nucleus, possibly with a role in gene regulation. Here we report that, in fact, a substantial fraction of all human miRNAs...

Showing 1 to 2 of 2 entries