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Showing 1 to 8 of 8 entries
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CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish.

Developmental dynamics : an official publication of the American Association of Anatomists

González F.
PMID: 27145095
Dev Dyn. 2016 Jul;245(7):788-806. doi: 10.1002/dvdy.24414. Epub 2016 Jun 09.

Because of their extraordinary differentiation potential, human pluripotent stem cells (hPSCs) can differentiate into virtually any cell type of the human body, providing a powerful platform not only for generating relevant cell types useful for cell replacement therapies, but...

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González F. CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish. Dev Dyn. 2016;245(7):788-806doi: 10.1002/dvdy.24414.
González, F. (2016). CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish. Developmental dynamics : an official publication of the American Association of Anatomists, 245(7), 788-806. https://doi.org/10.1002/dvdy.24414
González, Federico. "CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish." Developmental dynamics : an official publication of the American Association of Anatomists vol. 245,7 (2016): 788-806. doi: https://doi.org/10.1002/dvdy.24414
González F. CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish. Dev Dyn. 2016 Jul;245(7):788-806. doi: 10.1002/dvdy.24414. Epub 2016 Jun 09. PMID: 27145095.
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Induced pluripotent stem cells as a next-generation biomedical interface.

Laboratory investigation; a journal of technical methods and pathology

Hankowski KE, Hamazaki T, Umezawa A, Terada N.
PMID: 21555998
Lab Invest. 2011 Jul;91(7):972-7. doi: 10.1038/labinvest.2011.85. Epub 2011 May 09.

Recent advances in DNA sequencing technologies and subsequent progress in genome-wide association study (GWAS) are rapidly changing the landscape of human diseases. Our knowledge on disease-gene linkage has been exponentially growing, and soon we will obtain complete maps of...

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Hankowski KE, Hamazaki T, Umezawa A, et al. Induced pluripotent stem cells as a next-generation biomedical interface. Lab Invest. 2011;91(7):972-7doi: 10.1038/labinvest.2011.85.
Hankowski, K. E., Hamazaki, T., Umezawa, A., & Terada, N. (2011). Induced pluripotent stem cells as a next-generation biomedical interface. Laboratory investigation; a journal of technical methods and pathology, 91(7), 972-7. https://doi.org/10.1038/labinvest.2011.85
Hankowski, Katherine E, et al. "Induced pluripotent stem cells as a next-generation biomedical interface." Laboratory investigation; a journal of technical methods and pathology vol. 91,7 (2011): 972-7. doi: https://doi.org/10.1038/labinvest.2011.85
Hankowski KE, Hamazaki T, Umezawa A, Terada N. Induced pluripotent stem cells as a next-generation biomedical interface. Lab Invest. 2011 Jul;91(7):972-7. doi: 10.1038/labinvest.2011.85. Epub 2011 May 09. PMID: 21555998; PMCID: PMC3727242.
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Genome Editing in Human Neural Stem and Progenitor Cells.

Results and problems in cell differentiation

Bressan RB, Pollard SM.
PMID: 30209659
Results Probl Cell Differ. 2018;66:163-182. doi: 10.1007/978-3-319-93485-3_7.

Experimental tools for precise manipulation of mammalian genomes enable reverse genetic approaches to explore biology and disease. Powerful genome editing technologies built upon designer nucleases, such as CRISPR/Cas9, have recently emerged. Parallel progress has been made in methodologies for...

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Bressan RB, Pollard SM. Genome Editing in Human Neural Stem and Progenitor Cells. Results Probl Cell Differ. 2018;66:163-182doi: 10.1007/978-3-319-93485-3_7.
Bressan, R. B., & Pollard, S. M. (2018). Genome Editing in Human Neural Stem and Progenitor Cells. Results and problems in cell differentiation, 66163-182. https://doi.org/10.1007/978-3-319-93485-3_7
Bressan, Raul Bardini, and Pollard, Steven M. "Genome Editing in Human Neural Stem and Progenitor Cells." Results and problems in cell differentiation vol. 66 (2018): 163-182. doi: https://doi.org/10.1007/978-3-319-93485-3_7
Bressan RB, Pollard SM. Genome Editing in Human Neural Stem and Progenitor Cells. Results Probl Cell Differ. 2018;66:163-182. doi: 10.1007/978-3-319-93485-3_7. PMID: 30209659.
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Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead.

Molecular therapy : the journal of the American Society of Gene Therapy

Narsinh KH, Wu JC.
PMID: 20514030
Mol Ther. 2010 Jun;18(6):1061-3. doi: 10.1038/mt.2010.92.

No abstract available.

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Narsinh KH, Wu JC. Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead. Mol Ther. 2010;18(6):1061-3doi: 10.1038/mt.2010.92.
Narsinh, K. H., & Wu, J. C. (2010). Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead. Molecular therapy : the journal of the American Society of Gene Therapy, 18(6), 1061-3. https://doi.org/10.1038/mt.2010.92
Narsinh, Kazim H, and Wu, Joseph C. "Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead." Molecular therapy : the journal of the American Society of Gene Therapy vol. 18,6 (2010): 1061-3. doi: https://doi.org/10.1038/mt.2010.92
Narsinh KH, Wu JC. Gene correction in human embryonic and induced pluripotent stem cells: promises and challenges ahead. Mol Ther. 2010 Jun;18(6):1061-3. doi: 10.1038/mt.2010.92. PMID: 20514030; PMCID: PMC2889735.
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Array-comparative genomic hybridization characterization of human pluripotent stem cells.

Methods in molecular biology (Clifton, N.J.)

Elliott AM, Elliott KA, Kammesheidt A.
PMID: 22528361
Methods Mol Biol. 2012;873:261-7. doi: 10.1007/978-1-61779-794-1_17.

During culture adaptation, human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) tend to acquire chromosomal aberrations. Generally, stem cell lines are screened for large-scale chromosomal changes using low resolution karyotype analysis. Recent studies characterizing human stem...

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Elliott AM, Elliott KA, Kammesheidt A. Array-comparative genomic hybridization characterization of human pluripotent stem cells. Methods Mol Biol. 2012;873:261-7doi: 10.1007/978-1-61779-794-1_17.
Elliott, A. M., Elliott, K. A., & Kammesheidt, A. (2012). Array-comparative genomic hybridization characterization of human pluripotent stem cells. Methods in molecular biology (Clifton, N.J.), 873261-7. https://doi.org/10.1007/978-1-61779-794-1_17
Elliott, Aaron M, et al. "Array-comparative genomic hybridization characterization of human pluripotent stem cells." Methods in molecular biology (Clifton, N.J.) vol. 873 (2012): 261-7. doi: https://doi.org/10.1007/978-1-61779-794-1_17
Elliott AM, Elliott KA, Kammesheidt A. Array-comparative genomic hybridization characterization of human pluripotent stem cells. Methods Mol Biol. 2012;873:261-7. doi: 10.1007/978-1-61779-794-1_17. PMID: 22528361.
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Improving single-cell cloning workflow for gene editing in human pluripotent stem cells.

Stem cell research

Chen YH, Pruett-Miller SM.
PMID: 30099335
Stem Cell Res. 2018 Aug;31:186-192. doi: 10.1016/j.scr.2018.08.003. Epub 2018 Aug 04.

The availability of human pluripotent stem cells (hPSCs) and progress in genome engineering technology have altered the way we approach scientific research and drug development screens. Unfortunately, the procedures for genome editing of hPSCs often subject cells to harsh...

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Chen YH, Pruett-Miller SM. Improving single-cell cloning workflow for gene editing in human pluripotent stem cells. Stem Cell Res. 2018;31:186-192doi: 10.1016/j.scr.2018.08.003.
Chen, Y. H., & Pruett-Miller, S. M. (2018). Improving single-cell cloning workflow for gene editing in human pluripotent stem cells. Stem cell research, 31186-192. https://doi.org/10.1016/j.scr.2018.08.003
Chen, Yi-Hsien, and Pruett-Miller, Shondra M. "Improving single-cell cloning workflow for gene editing in human pluripotent stem cells." Stem cell research vol. 31 (2018): 186-192. doi: https://doi.org/10.1016/j.scr.2018.08.003
Chen YH, Pruett-Miller SM. Improving single-cell cloning workflow for gene editing in human pluripotent stem cells. Stem Cell Res. 2018 Aug;31:186-192. doi: 10.1016/j.scr.2018.08.003. Epub 2018 Aug 04. PMID: 30099335.
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The transcriptome of human pluripotent stem cells.

Current opinion in genetics & development

Au KF, Sebastiano V.
PMID: 25461453
Curr Opin Genet Dev. 2014 Oct;28:71-7. doi: 10.1016/j.gde.2014.09.012. Epub 2014 Oct 27.

Human Embryonic Stem Cells (hESCs) are in vitro derivatives of the inner cell mass of the blastocyst and are characterized by an undifferentiated and pluripotent state that can be perpetuated in time, indefinitely. hESCs provide a unique opportunity to...

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Au KF, Sebastiano V. The transcriptome of human pluripotent stem cells. Curr Opin Genet Dev. 2014;28:71-7doi: 10.1016/j.gde.2014.09.012.
Au, K. F., & Sebastiano, V. (2014). The transcriptome of human pluripotent stem cells. Current opinion in genetics & development, 2871-7. https://doi.org/10.1016/j.gde.2014.09.012
Au, Kin Fai, and Sebastiano, Vittorio. "The transcriptome of human pluripotent stem cells." Current opinion in genetics & development vol. 28 (2014): 71-7. doi: https://doi.org/10.1016/j.gde.2014.09.012
Au KF, Sebastiano V. The transcriptome of human pluripotent stem cells. Curr Opin Genet Dev. 2014 Oct;28:71-7. doi: 10.1016/j.gde.2014.09.012. Epub 2014 Oct 27. PMID: 25461453.
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Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs.

Scientific reports

Dodsworth BT, Hatje K, Rostovskaya M, Flynn R, Meyer CA, Cowley SA.
PMID: 32601281
Sci Rep. 2020 Jun 29;10(1):10542. doi: 10.1038/s41598-020-67376-w.

Naïve human pluripotent stem cells (hPSC) resemble the embryonic epiblast at an earlier time-point in development than conventional, 'primed' hPSC. We present a comprehensive miRNA profiling of naïve-to-primed transition in hPSC, a process recapitulating aspects of early in vivo...

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Dodsworth BT, Hatje K, Rostovskaya M, et al. Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs. Sci Rep. 2020;10(1):10542doi: 10.1038/s41598-020-67376-w.
Dodsworth, B. T., Hatje, K., Rostovskaya, M., Flynn, R., Meyer, C. A., & Cowley, S. A. (2020). Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs. Scientific reports, 10(1), 10542. https://doi.org/10.1038/s41598-020-67376-w
Dodsworth, Benjamin T, et al. "Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs." Scientific reports vol. 10,1 (2020): 10542. doi: https://doi.org/10.1038/s41598-020-67376-w
Dodsworth BT, Hatje K, Rostovskaya M, Flynn R, Meyer CA, Cowley SA. Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs. Sci Rep. 2020 Jun 29;10(1):10542. doi: 10.1038/s41598-020-67376-w. PMID: 32601281; PMCID: PMC7324611.
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Showing 1 to 8 of 8 entries