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Showing 1 to 12 of 462 entries
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Guest editorial. Computational systems biology.

IET systems biology

Chen L.
PMID: 24067411
IET Syst Biol. 2013 Oct;7(5):125. doi: 10.1049/iet-syb.2013.0019.

No abstract available.

SBpipe: a collection of pipelines for automating repetitive simulation and analysis tasks.

BMC systems biology

Dalle Pezze P, Le Novère N.
PMID: 28395655
BMC Syst Biol. 2017 Apr 10;11(1):46. doi: 10.1186/s12918-017-0423-3.

BACKGROUND: The rapid growth of the number of mathematical models in Systems Biology fostered the development of many tools to simulate and analyse them. The reliability and precision of these tasks often depend on multiple repetitions and they can...

Computational approaches for systems metabolomics.

Current opinion in biotechnology

Krumsiek J, Bartel J, Theis FJ.
PMID: 27135552
Curr Opin Biotechnol. 2016 Jun;39:198-206. doi: 10.1016/j.copbio.2016.04.009. Epub 2016 Apr 30.

Systems genetics is defined as the simultaneous assessment and analysis of multi-omics datasets. In the past few years, metabolomics has been established as a robust tool describing an important functional layer in this approach. The metabolome of a biological...

Computational Systems Biomedicine.

Briefings in bioinformatics

Dubitzky W.
PMID: 27193556
Brief Bioinform. 2016 May;17(3):367. doi: 10.1093/bib/bbw038.

No abstract available.

Can mechanistic explanation be reconciled with scale-free constitution and dynamics?.

Studies in history and philosophy of biological and biomedical sciences

Bechtel W.
PMID: 25977254
Stud Hist Philos Biol Biomed Sci. 2015 Oct;53:84-93. doi: 10.1016/j.shpsc.2015.03.006. Epub 2015 May 11.

This paper considers two objections to explanations that appeal to mechanisms to explain biological phenomena. Marom argues that the time-scale on which many phenomena occur is scale-free. There is also reason to suspect that the network of interacting entities...

Computationally guided design of robust gene circuits.

Methods in molecular biology (Clifton, N.J.)

Shah NA, Sarkar CA.
PMID: 25487097
Methods Mol Biol. 2015;1244:167-78. doi: 10.1007/978-1-4939-1878-2_8.

The inability to rationally design and construct circuits that robustly enable complex behaviors is perhaps the most fundamental challenge in synthetic biology. While systems modeling can aid this process and help reduce the space of design strategies, the unavailability...

Tools of discovery.

Molecular systems biology

Lemberger T.
PMID: 24408915
Mol Syst Biol. 2014 Jan 08;10:715. doi: 10.1002/msb.201305048. Print 2014.

No abstract available.

The International Conference on Intelligent Biology and Medicine (ICIBM) 2016: putting systems biology to work.

BMC systems biology

Zheng WJ, Ruan J, Xu H, Zhao Z, Liu Z.
PMID: 28984194
BMC Syst Biol. 2017 Oct 03;11:88. doi: 10.1186/s12918-017-0461-x.

Between December 8-10, 2016, the International Conference on Intelligent Biology and Medicine (ICIBM 2016) was held in Houston, Texas, USA. The conference included eight scientific sessions, four tutorials, one poster session, four highlighted talks and four keynotes that covered...

Harnessing MOOCs for the Practice of Science.

Cell systems

Mak HC.
PMID: 28957647
Cell Syst. 2017 Sep 27;5(3):157. doi: 10.1016/j.cels.2017.09.007.

No abstract available.

Cross-disorder comparative analysis of comorbid conditions reveals novel autism candidate genes.

BMC genomics

Diaz-Beltran L, Esteban FJ, Varma M, Ortuzk A, David M, Wall DP.
PMID: 28427329
BMC Genomics. 2017 Apr 20;18(1):315. doi: 10.1186/s12864-017-3667-9.

BACKGROUND: Numerous studies have highlighted the elevated degree of comorbidity associated with autism spectrum disorder (ASD). These comorbid conditions may add further impairments to individuals with autism and are substantially more prevalent compared to neurotypical populations. These high rates...

Airway remodeling: Systems biology approach, from bench to bedside.

Technology and health care : official journal of the European Society for Engineering and Medicine

Najafi A, Ghanei M, Jamalkandi SA.
PMID: 27315153
Technol Health Care. 2016 Nov 14;24(6):811-819. doi: 10.3233/THC-161228.

Airway Remodeling, a patho-physiologic process, is considered as a key feature of chronic airway diseases. In recent years, our understanding of the complex diseases has increased significantly by the use of combined approaches, including systems biology, which may contribute...

Applying Systems Biology Methodology To Identify Genetic Factors Possibly Associated with Recovery after Traumatic Brain Injury.

Journal of neurotrauma

Kurowski BG, Treble-Barna A, Pitzer AJ, Wade SL, Martin LJ, Chima RS, Jegga A.
PMID: 28301983
J Neurotrauma. 2017 Jul 15;34(14):2280-2290. doi: 10.1089/neu.2016.4856. Epub 2017 May 03.

Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality worldwide. It is linked with a number of medical, neurological, cognitive, and behavioral sequelae. The influence of genetic factors on the biology and related recovery...

Showing 1 to 12 of 462 entries