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Showing 1 to 12 of 152 entries
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Simultaneous Quantification of 11 Constituents in Wuji Pill Using Ultra Performance Liquid Chromatography Coupled With a Triple Quadrupole Electrospray Tandem Mass Spectrometry.

Journal of chromatographic science

Tian T, Jin Y, Ma Y, Xie W, Xu H, Du Y.
PMID: 26363492
J Chromatogr Sci. 2016 Feb;54(2):237-45. doi: 10.1093/chromsci/bmv140. Epub 2015 Sep 12.

An ultra performance liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry (UPLC-MS-MS) method was developed for analyzing and identifying the constituents of 11 compounds including berberine, epiberberine, berberrubine, jatrorrhizine, coptisine, palmatine, evodiamine, rutaecarpine, limonin, paeoniflorin and...

Using SEQUEST with theoretically complete sequence databases.

Journal of the American Society for Mass Spectrometry

Sadygov RG.
PMID: 26238326
J Am Soc Mass Spectrom. 2015 Nov;26(11):1858-64. doi: 10.1007/s13361-015-1228-5. Epub 2015 Aug 04.

SEQUEST has long been used to identify peptides/proteins from their tandem mass spectra and protein sequence databases. The algorithm has proven to be hugely successful for its sensitivity and specificity in identifying peptides/proteins, the sequences of which are present...

High-throughput online solid-phase extraction tandem mass spectrometry: Is it right for your clinical laboratory?.

Clinical biochemistry

Jannetto PJ, Langman LJ.
PMID: 27129800
Clin Biochem. 2016 Sep;49(13):1032-4. doi: 10.1016/j.clinbiochem.2016.04.012. Epub 2016 Apr 27.

With increasing patient volumes and growing demands for rapid turnaround on many clinical tests, there is a demand for high-throughput technologies. High-Throughput Online Solid-Phase Extraction Tandem Mass Spectrometry is an example of one technology that can achieve these desired...

Fragmentation pathways and structural characterization of 14 nerve agent compounds by electrospray ionization tandem mass spectrometry.

Journal of analytical toxicology

Housman KJ, Swift AT, Oyler JM.
PMID: 25519457
J Anal Toxicol. 2015 Mar;39(2):96-105. doi: 10.1093/jat/bku135. Epub 2014 Dec 16.

Organophosphate nerve agents (OPNAs) are some of the most widely used and proliferated chemical warfare agents. As evidenced by recent events in Syria, these compounds remain a serious military and terrorist threat to human health because of their toxicity...

Isolation, Chemical Fingerprinting and Simultaneous Quantification of Four Compounds from Tanacetum gracile Using a Validated HPLC-ESI-QTOF-Mass Spectrometry Method.

Journal of chromatographic science

Sharma N, Kumar C, Dutt P, Gupta S, Satti NK, Chandra S, Kitchlu S, Paul S, Vishwakarma RA, Verma MK.
PMID: 26951542
J Chromatogr Sci. 2016 May-Jun;54(5):796-804. doi: 10.1093/chromsci/bmw013. Epub 2016 Mar 06.

The present study was conducted to carry out the phytochemical investigation of Tanacetum gracile Hook. f. & Thomson and to develop a method for the simultaneous quantification of the isolated compounds in the extracts ofT. gracile growing in different...

Simultaneous quantitation and comparison of eight components in Jiao-ai decoction and Si-wu decoction by ultra high performance liquid chromatography with triple quadrupole tandem mass spectrometry.

Journal of separation science

Yao W, Li H, Liu Q, Gao Y, Dai J, Bao B, Zhang L, Ding A, Tang Y, Duan J.
PMID: 27384525
J Sep Sci. 2016 Sep;39(17):3311-7. doi: 10.1002/jssc.201600456. Epub 2016 Aug 04.

An ultra high performance liquid chromatography coupled to triple quadrupole tandem mass spectrometry method has been established to evaluate the variations of multiple components of Chinese herbal preparations, Jiao-ai decoction and Si-wu decoction, through the simultaneous determination of eight...

Multi-mode acquisition (MMA): An MS/MS acquisition strategy for maximizing selectivity, specificity and sensitivity of DIA product ion spectra.

Proteomics

Williams BJ, Ciavarini SJ, Devlin C, Cohn SM, Xie R, Vissers JP, Martin LB, Caswell A, Langridge JI, Geromanos SJ.
PMID: 27296928
Proteomics. 2016 Aug;16(15):2284-301. doi: 10.1002/pmic.201500492.

In proteomics studies, it is generally accepted that depth of coverage and dynamic range is limited in data-directed acquisitions. The serial nature of the method limits both sensitivity and the number of precursor ions that can be sampled. To...

Workflows for automated downstream data analysis and visualization in large-scale computational mass spectrometry.

Proteomics

Aiche S, Sachsenberg T, Kenar E, Walzer M, Wiswedel B, Kristl T, Boyles M, Duschl A, Huber CG, Berthold MR, Reinert K, Kohlbacher O.
PMID: 25604327
Proteomics. 2015 Apr;15(8):1443-7. doi: 10.1002/pmic.201400391. Epub 2015 Feb 14.

MS-based proteomics and metabolomics are rapidly evolving research fields driven by the development of novel instruments, experimental approaches, and analysis methods. Monolithic analysis tools perform well on single tasks but lack the flexibility to cope with the constantly changing...

Computational mass spectrometry for metabolomics: identification of metabolites and small molecules.

Analytical and bioanalytical chemistry

Neumann S, Böcker S.
PMID: 20936272
Anal Bioanal Chem. 2010 Dec;398(7):2779-88. doi: 10.1007/s00216-010-4142-5. Epub 2010 Oct 09.

The identification of compounds from mass spectrometry (MS) data is still seen as a major bottleneck in the interpretation of MS data. This is particularly the case for the identification of small compounds such as metabolites, where until recently...

Early synthetic dyes--a challenge for tandem mass spectrometry.

Journal of mass spectrometry : JMS

Lech K, Wilicka E, Witowska-Jarosz J, Jarosz M.
PMID: 23378085
J Mass Spectrom. 2013 Feb;48(2):141-7. doi: 10.1002/jms.3090.

The present study concerns identification of early yellow synthetic dyes from silk fibers taken from the 1930 spring color palette of the Lyon Dyers' Guild (La Chambre Syndicale des Teinturiers). The identification was based mainly on the electrospray ionization...

A direct sensitivity comparison between flow-modulated comprehensive 2D and 1D GC in untargeted and targeted MS-based experiments.

Journal of separation science

Tranchida PQ, Franchina FA, Zoccali M, Bonaccorsi I, Cacciola F, Mondello L.
PMID: 23868497
J Sep Sci. 2013 Sep;36(17):2746-52. doi: 10.1002/jssc.201300423. Epub 2013 Jul 19.

The present contribution is focused on the measurement of the analytical sensitivity attained in untargeted/targeted MS/MS experiments, performed using flow-modulator comprehensive 2D and 1D GC. The comprehensive 2D experiment was performed by diverting part of the high flow (circa...

Qualitative and quantitative determination of nine main active constituents in Pulsatilla cernua by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry.

Journal of separation science

Xu H, Shi X, Ji X, Du Y, Zhu H, Zhang L.
PMID: 21268254
J Sep Sci. 2011 Feb;34(3):308-16. doi: 10.1002/jssc.201000660. Epub 2011 Jan 03.

A novel qualitative and quantitative method using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) was developed for simultaneous determination of the nine major active constituents in Pulsatilla cernua (Thunb.) Bercht. et Opiz., namely anemoside A3...

Showing 1 to 12 of 152 entries