Display options
Cite
Xiang Z, Yang Y, Ma X, et al. Microarray expression profiling: analysis and applications. Curr Opin Drug Discov Devel. 2003;6(3):384-95
Xiang, Z., Yang, Y., Ma, X., & Ding, W. (2003). Microarray expression profiling: analysis and applications. Current opinion in drug discovery & development, 6(3), 384-95.
Xiang, Zhaoying, et al. "Microarray expression profiling: analysis and applications." Current opinion in drug discovery & development vol. 6,3 (2003): 384-95.
Xiang Z, Yang Y, Ma X, Ding W. Microarray expression profiling: analysis and applications. Curr Opin Drug Discov Devel. 2003 May;6(3):384-95. PMID: 12833672.
Copy Download .nbib Format: NLM
Share it on

Curr Opin Drug Discov Devel. 2003 May;6(3):384-95.

Microarray expression profiling: analysis and applications.

Current opinion in drug discovery & development

Zhaoying Xiang, Yaning Yang, Xiaojing Ma, Wei Ding

Affiliations

  1. Weill Medical College of Cornell University, Department of Microbiology & Immunology, 1300 York Avenue, New York, NY 10021, USA.

PMID: 12833672

Abstract

Recent advances in the technology of massive parallel gene expression profiling using microarrays are revolutionizing biomedical research and pharmacological discovery. These new and powerful tools allow researchers to examine the dynamics of a whole biological system by simultaneously interrogating the expression of tens of thousands of genes. This article will review the various bioinformatics and statistical methods commonly used to analyze the enormous amounts of data generated by this technology. The objective of these analyses is to reliably extract important biological information from carefully designed and controlled microarray experiments, and to organize the information in ways that reveal structured and coordinated physiological processes and key components controlling the biological responses studied. The major applications of the microarray technology, recently used to address a variety of biological questions of interest to scientists and clinicians in academia, healthcare and the pharmaceutical industry, will also be presented.

MeSH terms

Publication Types

Grant support