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Holtzapple MT, Caram HS, Humphrey AE. The HCH-1 model of enzymatic cellulose hydrolysis. Biotechnol Bioeng. 1984;26(7):775-80doi: 10.1002/bit.260260723.
Holtzapple, M. T., Caram, H. S., & Humphrey, A. E. (1984). The HCH-1 model of enzymatic cellulose hydrolysis. Biotechnology and bioengineering, 26(7), 775-80. https://doi.org/10.1002/bit.260260723
Holtzapple, M T, et al. "The HCH-1 model of enzymatic cellulose hydrolysis." Biotechnology and bioengineering vol. 26,7 (1984): 775-80. doi: https://doi.org/10.1002/bit.260260723
Holtzapple MT, Caram HS, Humphrey AE. The HCH-1 model of enzymatic cellulose hydrolysis. Biotechnol Bioeng. 1984 Jul;26(7):775-80. doi: 10.1002/bit.260260723. PMID: 18553446.
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Biotechnol Bioeng. 1984 Jul;26(7):775-80. doi: 10.1002/bit.260260723.

The HCH-1 model of enzymatic cellulose hydrolysis.

Biotechnology and bioengineering

M T Holtzapple, H S Caram, A E Humphrey

Affiliations

  1. US Army Natick R&D Laboratories, Natick, Massachusetts 01760, USA.

PMID: 18553446 DOI: 10.1002/bit.260260723

Abstract

Solka Floc BW200 was enzymatically hydrolyzed in a batch reactor using a commercial cellulase preparation. A total of 50 different hydrolysis conditions were run within a 10-fold range in enzyme concentration and a 30-fold range in cellulose concentration. The data were evaluated in three ways using five different models. Previous literature models were not as successful in correlating the data as the HCH-1 Model derived in this work.

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