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Zhao H, Wang D, Du W, et al. MicroRNA and leukemia: tiny molecule, great function. Crit Rev Oncol Hematol. 2009;74(3):149-55doi: 10.1016/j.critrevonc.2009.05.001.
Zhao, H., Wang, D., Du, W., Gu, D., & Yang, R. (2010). MicroRNA and leukemia: tiny molecule, great function. Critical reviews in oncology/hematology, 74(3), 149-55. https://doi.org/10.1016/j.critrevonc.2009.05.001
Zhao, Haifeng, et al. "MicroRNA and leukemia: tiny molecule, great function." Critical reviews in oncology/hematology vol. 74,3 (2010): 149-55. doi: https://doi.org/10.1016/j.critrevonc.2009.05.001
Zhao H, Wang D, Du W, Gu D, Yang R. MicroRNA and leukemia: tiny molecule, great function. Crit Rev Oncol Hematol. 2010 Jun;74(3):149-55. doi: 10.1016/j.critrevonc.2009.05.001. Epub 2009 Jun 10. PMID: 19520590.
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Crit Rev Oncol Hematol. 2010 Jun;74(3):149-55. doi: 10.1016/j.critrevonc.2009.05.001. Epub 2009 Jun 10.

MicroRNA and leukemia: tiny molecule, great function.

Critical reviews in oncology/hematology

Haifeng Zhao, Donghai Wang, Weiting Du, Dongsheng Gu, Renchi Yang

Affiliations

  1. State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 288 Nanjing Road, Tianjin 300020, PR China.

PMID: 19520590 DOI: 10.1016/j.critrevonc.2009.05.001

Abstract

MicroRNAs are small noncoding RNA molecules that negatively regulate gene expression via degradation or translational repression of their targeted messenger RNAs (mRNAs). It is known that aberrant microRNA expression can play a vital role in the pathology of leukemia, thus microRNAs have rapidly emerged as potential targets for therapeutics. This review focuses on recent researches on the important roles of microRNAs in the pathogenesis of leukemia, including acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL).

Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.

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